Details for: Gpx1

Gene ID: 14775

Symbol: Gpx1

Ensembl ID: ENSMUSG00000063856

Description: glutathione peroxidase 1

Associated with

Other Information

Genular Protein ID: 2735469936

Symbol: GPX1_MOUSE

Name: Cellular glutathione peroxidase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 3015592

Title: The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the 'termination' codon, TGA.

PubMed ID: 3015592

DOI: 10.1002/j.1460-2075.1986.tb04350.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2771650

Title: A human cDNA sequence for a novel glutathione peroxidase-related selenopeptide, GPRP.

PubMed ID: 2771650

DOI: 10.1093/nar/17.15.6390

PubMed ID: 9126277

Title: The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver.

PubMed ID: 9126277

DOI: 10.1006/abbi.1997.9901

PubMed ID: 9195979

Title: Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia.

PubMed ID: 9195979

DOI: 10.1074/jbc.272.26.16644

PubMed ID: 9712879

Title: Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

PubMed ID: 9712879

DOI: 10.1074/jbc.273.35.22528

PubMed ID: 10754271

Title: Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene.

PubMed ID: 10754271

DOI: 10.1016/s0891-5849(00)00161-1

PubMed ID: 17503775

Title: SelT, SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family.

PubMed ID: 17503775

DOI: 10.1021/bi602462q

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21420488

Title: Knockout of SOD1 promotes conversion of selenocysteine to dehydroalanine in murine hepatic GPX1 protein.

PubMed ID: 21420488

DOI: 10.1016/j.freeradbiomed.2011.03.018

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 32358195

Title: Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity.

PubMed ID: 32358195

DOI: 10.1073/pnas.2001387117

PubMed ID: 36608588

Title: Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides.

PubMed ID: 36608588

DOI: 10.1016/j.redox.2022.102593

Sequence Information:

  • Length: 201
  • Mass: 22329
  • Checksum: 401D065165D8AF5C
  • Sequence:
  • MCAARLSAAA QSTVYAFSAR PLTGGEPVSL GSLRGKVLLI ENVASLUGTT IRDYTEMNDL 
    QKRLGPRGLV VLGFPCNQFG HQENGKNEEI LNSLKYVRPG GGFEPNFTLF EKCEVNGEKA 
    HPLFTFLRNA LPTPSDDPTA LMTDPKYIIW SPVCRNDIAW NFEKFLVGPD GVPVRRYSRR 
    FRTIDIEPDI ETLLSQQSGN S

Genular Protein ID: 81395358

Symbol: A0A0A6YVV2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

Sequence Information:

  • Length: 145
  • Mass: 16483
  • Checksum: 1ED8112B7B709E56
  • Sequence:
  • MNDLQKRLGP RGLVVLGFPC NQFGHQENGK NEEILNSLKY VRPGGGFEPN FTLFEKCEVN 
    GEKAHPLFTF LRNALPTPSD DPTALMTDPK YIIWSPVCRN DIAWNFEKFL VGPDGVPVRR 
    YSRRFRTIDI EPDIETLLSQ QSGNS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.