Details for: Spsb2

Gene ID: 14794

Symbol: Spsb2

Ensembl ID: ENSMUSG00000038451

Description: splA/ryanodine receptor domain and SOCS box containing 2

Associated with

Other Information

Genular Protein ID: 2019513297

Symbol: SPSB2_MOUSE

Name: SPRY domain-containing SOCS box protein 2

UniProtKB Accession Codes:

O88838 Q8CBA5 Q91Z15

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 EMBL 6 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 Gene3D 2 GeneTree 1 Genevisible 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 6 SAM 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9445485

Title: Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6.

PubMed ID: 9445485

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20603330

Title: The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation.

PubMed ID: 20603330

DOI: 10.1083/jcb.200912087

PubMed ID: 20561531

Title: Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.

PubMed ID: 20561531

DOI: 10.1016/j.jmb.2010.06.017

PubMed ID: 16369487

Title: The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.

PubMed ID: 16369487

DOI: 10.1038/nsmb1034

Sequence Information:

  • Length: 264
  • Mass: 28938
  • Checksum: E71985597D9B38CB
  • Sequence:
    • MGQTALARGS SSTPTSQALY SDFSPPEGLE ELLSAPPPDL VAQRHHGWNP KDCSENIDVK 
EGGLCFERRP VAQSTDGVRG KRGYSRGLHA WEISWPLEQR GTHAVVGVAT ALAPLQADHY 
AALLGSNSES WGWDIGRGKL YHQSKGLEAP QYPAGPQGEQ LVVPERLLVV LDMEEGTLGY 
SIGGTYLGPA FRGLKGRTLY PSVSAVWGQC QVRIRYMGER RVEEPQSLLH LSRLCVRHAL 
GDTRLGQIST LPLPPAMKRY LLYK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.