Genular: Defining Cellular Identity and Function

Details for: Grik2

Gene ID: 14806

Symbol: Grik2

Ensembl ID: ENSMUSG00000056073

Description: glutamate receptor, ionotropic, kainate 2 (beta 2)

Associated with

Activation of ca-permeable kainate receptor
(R-MMU-451308)
Activation of kainate receptors upon glutamate binding
(R-MMU-451326)
Activation of na-permeable kainate receptors
(R-MMU-451307)
Ionotropic activity of kainate receptors
(R-MMU-451306)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Transmission across chemical synapses
(R-MMU-112315)
Axon
(GO:0030424)
Behavioral fear response
(GO:0001662)
Chemical synaptic transmission
(GO:0007268)
Dendrite
(GO:0030425)
Dendrite cytoplasm
(GO:0032839)
Detection of cold stimulus involved in thermoception
(GO:0120169)
Excitatory postsynaptic potential
(GO:0060079)
Extracellularly glutamate-gated ion channel activity
(GO:0005234)
Glutamate-gated receptor activity
(GO:0004970)
Glutamate receptor activity
(GO:0008066)
Glutamatergic synapse
(GO:0098978)
Hippocampal mossy fiber to ca3 synapse
(GO:0098686)
Identical protein binding
(GO:0042802)
Inhibitory postsynaptic potential
(GO:0060080)
Intracellular calcium ion homeostasis
(GO:0006874)
Ionotropic glutamate receptor complex
(GO:0008328)
Kainate selective glutamate receptor activity
(GO:0015277)
Kainate selective glutamate receptor complex
(GO:0032983)
Ligand-gated monoatomic ion channel activity
(GO:0015276)
Ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
(GO:0099507)
Membrane
(GO:0016020)
Modulation of chemical synaptic transmission
(GO:0050804)
Modulation of excitatory postsynaptic potential
(GO:0098815)
Monoatomic ion channel activity
(GO:0005216)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Mossy fiber rosette
(GO:0097471)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of synaptic transmission, glutamatergic
(GO:0051967)
Neuronal action potential
(GO:0019228)
Neuronal cell body
(GO:0043025)
Neuron apoptotic process
(GO:0051402)
Pdz domain binding
(GO:0030165)
Perikaryon
(GO:0043204)
Plasma membrane
(GO:0005886)
Positive regulation of neuron apoptotic process
(GO:0043525)
Positive regulation of synaptic transmission
(GO:0050806)
Postsynaptic density
(GO:0014069)
Postsynaptic density membrane
(GO:0098839)
Postsynaptic membrane
(GO:0045211)
Presynaptic membrane
(GO:0042734)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein binding
(GO:0005515)
Receptor clustering
(GO:0043113)
Regulation of jnk cascade
(GO:0046328)
Regulation of long-term neuronal synaptic plasticity
(GO:0048169)
Regulation of membrane potential
(GO:0042391)
Regulation of short-term neuronal synaptic plasticity
(GO:0048172)
Scaffold protein binding
(GO:0097110)
Signaling receptor activity
(GO:0038023)
Snare binding
(GO:0000149)
Synapse
(GO:0045202)
Synaptic transmission, glutamatergic
(GO:0035249)
Terminal bouton
(GO:0043195)
Transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
(GO:1904315)
Ubiquitin conjugating enzyme binding
(GO:0031624)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

A0A1W2P6S5_MOUSE

Genular Protein ID: 1535096726

Symbol: A0A1W2P6S5_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A1W2P6S5

Database IDs:

Citations:

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.T500041-MCP200

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 893
Mass: 100261
Checksum: ABFEAA3E74452042
Sequence:

MKIISPVLSN LVFSRSIKVL LCLLWIGYSQ GTTHVLRFGG IFEYVESGPM GAEELAFRFA 
VNTINRNRTL LPNTTLTYDT QKINLYDSFE ASKKACDQLS LGVAAIFGPS HSSSANAVQS 
ICNALGVPHI QTRWKHQVSD NKDSFYVSLY PDFSSLSRAI LDLVQFFKWK TVTVVYDDST 
GLIRLQELIK APSRYNLRLK IRQLPADTKD AKPLLKEMKR GKEFHVIFDC SHEMAAGILK 
QALAMGMMTE YYHYIFTTLD LFALDVEPYR YSGVNMTGFR ILNTENTQVS SIIEKWSMER 
LQAPPKPDSG LLDGFMTTDA ALMYDAVHVV SVAVQQFPQM TVSSLQCNRH KPWRFGTRFM 
SLIKEAHWEG LTGRITFNKT NGLRTDFDLD VISLKEEGLE KIGTWDPSSG LNMTESQKGK 
PANITDSLSN RSLIVTTILE EPYVLFKKSD KPLYGNDRFE GYCIDLLREL STILGFTYEI 
RLVEDGKYGA QDDVNGQWNG MVRELIDHKA DLAVAPLAIT YVREKVIDFS KPFMTLGISI 
LYRKPNGTNP GVFSFLNPLS PDIWMYILLA YLGVSCVLFV IARFSPYEWY NPHPCNPDSD 
VVENNFTLLN SFWFGVGALM QQGSELMPKA LSTRIVGGIW WFFTLIIISS YTANLAAFLT 
VERMESPIDS ADDLAKQTKI EYGAVEDGAT MTFFKKSKIS TYDKMWAFMS SRRQSVLVKS 
NEEGIQRVLT SDYAFLMEST TIEFVTQRNC NLTQIGGLID SKGYGVGTPM GSPYRDKITI 
AILQLQEEGK LHMMKEKWWR GNGCPEEESK EASALGVQNI GGIFIVLAAG LVLSVFVAVG 
EFLYKSKKNA QLEKKVKTIL PQDNVFLPLL ESDFSISTVL SSSPSSSSLS SCC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.