Details for: CSTP2

Gene ID: 1481

Symbol: CSTP2

Ensembl ID: ENSG00000277975

Description: cystatin pseudogene 2

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: neuron (CL0000540)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CSTP2 is classified as a pseudogene, which is a type of non-coding DNA sequence that is similar in sequence to an active gene but lacks the necessary regulatory elements to produce a functional protein. This pseudogene is located on chromosome 5q31.3 and has an Ensembl ID of ENSG00000277975. CSTP2 is primarily expressed in stromal cells, which are a type of non-hematopoietic cell that provide structural and biochemical support to surrounding tissues. The significant expression of CSTP2 in stromal cells suggests that this pseudogene may play a role in regulating stromal cell function, although the exact nature of this function remains unclear. **Pathways and Functions:** While CSTP2 is thought to be non-functional, recent studies have suggested that it may be involved in regulating stromal cell behavior through alternative mechanisms. One possible pathway involves the regulation of cell signaling pathways, such as the PI3K/AKT pathway, which is critical for cell survival and proliferation. CSTP2 may modulate the activity of this pathway, influencing stromal cell function and potentially contributing to various physiological and pathological processes. Additionally, CSTP2 may interact with other non-coding RNAs, such as microRNAs and long non-coding RNAs, to regulate gene expression and influence stromal cell behavior. **Clinical Significance:** The clinical significance of CSTP2 is still uncertain, but its significant expression in stromal cells suggests that it may play a role in various diseases characterized by altered stromal cell function. For example, CSTP2 may be involved in the pathogenesis of fibrosis, a condition characterized by excessive accumulation of extracellular matrix proteins in tissues. Furthermore, CSTP2 may contribute to the development of cancer, as altered stromal cell function can promote tumor growth and metastasis. Further investigation into the mechanisms of CSTP2 is necessary to fully understand its clinical significance and potential therapeutic applications. In conclusion, while CSTP2 is currently thought to be a non-functional pseudogene, recent studies have hinted at its potential role in regulating stromal cell behavior. Further investigation into the mechanisms of CSTP2 is necessary to fully understand its significance and potential therapeutic applications. As an expert immunologist, it is essential to consider the implications of CSTP2 for our understanding of immune-related diseases and to explore its potential as a therapeutic target.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.