Genular: Defining Cellular Identity and Function

Details for: Grin1

Gene ID: 14810

Symbol: Grin1

Ensembl ID: ENSMUSG00000026959

Description: glutamate receptor, ionotropic, NMDA1 (zeta 1)

Associated with

Activation of nmda receptors and postsynaptic events
(R-MMU-442755)
Assembly and cell surface presentation of nmda receptors
(R-MMU-9609736)
Axon guidance
(R-MMU-422475)
Developmental biology
(R-MMU-1266738)
Eph-ephrin signaling
(R-MMU-2682334)
Ephb-mediated forward signaling
(R-MMU-3928662)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Nervous system development
(R-MMU-9675108)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Protein-protein interactions at synapses
(R-MMU-6794362)
Raf/map kinase cascade
(R-MMU-5673001)
Signal transduction
(R-MMU-162582)
Synaptic adhesion-like molecules
(R-MMU-8849932)
Transmission across chemical synapses
(R-MMU-112315)
Unblocking of nmda receptors, glutamate binding and activation
(R-MMU-438066)
Adult locomotory behavior
(GO:0008344)
Amyloid-beta binding
(GO:0001540)
Associative learning
(GO:0008306)
Calcium channel activity
(GO:0005262)
Calcium ion binding
(GO:0005509)
Calcium ion transport
(GO:0006816)
Calmodulin binding
(GO:0005516)
Cerebral cortex development
(GO:0021987)
Chemical synaptic transmission
(GO:0007268)
Conditioned taste aversion
(GO:0001661)
Enzyme binding
(GO:0019899)
Glutamate-gated calcium ion channel activity
(GO:0022849)
Glutamate-gated receptor activity
(GO:0004970)
Glutamate binding
(GO:0016595)
Glutamate receptor binding
(GO:0035254)
Glycine binding
(GO:0016594)
Intracellular calcium ion homeostasis
(GO:0006874)
Ionotropic glutamate receptor binding
(GO:0035255)
Ionotropic glutamate receptor signaling pathway
(GO:0035235)
Learning
(GO:0007612)
Learning or memory
(GO:0007611)
Ligand-gated monoatomic ion channel activity
(GO:0015276)
Ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
(GO:0099507)
Long-term memory
(GO:0007616)
Memory
(GO:0007613)
Monoatomic cation channel activity
(GO:0005261)
Monoatomic cation transport
(GO:0006812)
Monoatomic ion channel activity
(GO:0005216)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Negative regulation of neuron apoptotic process
(GO:0043524)
Neuromuscular process
(GO:0050905)
Nmda glutamate receptor activity
(GO:0004972)
Olfactory learning
(GO:0008355)
Phosphatase binding
(GO:0019902)
Pons maturation
(GO:0021586)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of calcium ion transport into cytosol
(GO:0010524)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Propylene metabolic process
(GO:0018964)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein heterotetramerization
(GO:0051290)
Regulation of axonogenesis
(GO:0050770)
Regulation of cell communication
(GO:0010646)
Regulation of dendrite morphogenesis
(GO:0048814)
Regulation of long-term neuronal synaptic plasticity
(GO:0048169)
Regulation of membrane potential
(GO:0042391)
Regulation of neuronal synaptic plasticity
(GO:0048168)
Regulation of neuron apoptotic process
(GO:0043523)
Regulation of respiratory gaseous exchange
(GO:0043576)
Regulation of synaptic plasticity
(GO:0048167)
Response to amphetamine
(GO:0001975)
Response to ethanol
(GO:0045471)
Response to morphine
(GO:0043278)
Rhythmic process
(GO:0048511)
Sensory perception of pain
(GO:0019233)
Signaling receptor activity
(GO:0038023)
Signaling receptor binding
(GO:0005102)
Social behavior
(GO:0035176)
Startle response
(GO:0001964)
Suckling behavior
(GO:0001967)
Synaptic transmission, glutamatergic
(GO:0035249)
Transcription by rna polymerase ii
(GO:0006366)
Transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
(GO:1904315)
Visual learning
(GO:0008542)
Voltage-gated monoatomic cation channel activity
(GO:0022843)

Other Information

Proteins

Glutamate receptor ionotropic, NMDA 1
A2AI16_MOUSE

Genular Protein ID: 739734244

Symbol: NMDZ1_MOUSE

Name: Glutamate receptor ionotropic, NMDA 1

UniProtKB Accession Codes:

P35438 A2AI15 A2AI18 Q8CFS4

Database IDs:

Citations:

PubMed ID: 1532151

Title: Cloning, expression and modulation of a mouse NMDA receptor subunit.

PubMed ID: 1532151

DOI: 10.1016/0014-5793(92)80160-i

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8060614

Title: Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death.

PubMed ID: 8060614

DOI: 10.1016/0896-6273(94)90350-6

PubMed ID: 12008020

Title: Cloning and characterization of a novel NMDA receptor subunit NR3B: a dominant subunit that reduces calcium permeability.

PubMed ID: 12008020

DOI: 10.1016/s0169-328x(02)00173-0

PubMed ID: 14602821

Title: Specific assembly with the NMDA receptor 3B subunit controls surface expression and calcium permeability of NMDA receptors.

PubMed ID: 14602821

DOI: 10.1523/jneurosci.23-31-10064.2003

PubMed ID: 18849881

Title: GRINL1A colocalizes with N-methyl D-aspartate receptor NR1 subunit and reduces N-methyl D-aspartate toxicity.

PubMed ID: 18849881

DOI: 10.1097/wnr.0b013e328317f05f

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23524343

Title: Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome.

PubMed ID: 23524343

DOI: 10.1038/nm.3117

Sequence Information:

Length: 938
Mass: 105481
Checksum: C610632DD3E06171
Sequence:

MSTMHLLTFA LLFSCSFARA ACDPKIVNIG AVLSTRKHEQ MFREAVNQAN KRHGSWKIQL 
NATSVTHKPN AIQMALSVCE DLISSQVYAI LVSHPPTPND HFTPTPVSYT AGFYRIPVLG 
LTTRMSIYSD KSIHLSFLRT VPPYSHQSSV WFEMMRVYNW NHIILLVSDD HEGRAAQKRL 
ETLLEERESK AEKVLQFDPG TKNVTALLME ARDLEARVII LSASEDDAAT VYRAAAMLNM 
TGSGYVWLVG EREISGNALR YAPDGIIGLQ LINGKNESAH ISDAVGVVAQ AVHELLEKEN 
ITDPPRGCVG NTNIWKTGPL FKRVLMSSKY ADGVTGRVEF NEDGDRKFAN YSIMNLQNRK 
LVQVGIYNGT HVIPNDRKII WPGGETEKPR GYQMSTRLKI VTIHQEPFVY VKPTMSDGTC 
KEEFTVNGDP VKKVICTGPN DTSPGSPRHT VPQCCYGFCV DLLIKLARTM NFTYEVHLVA 
DGKFGTQERV NNSNKKEWNG MMGELLSGQA DMIVAPLTIN NERAQYIEFS KPFKYQGLTI 
LVKKEIPRST LDSFMQPFQS TLWLLVGLSV HVVAVMLYLL DRFSPFGRFK VNSEEEEEDA 
LTLSSAMWFS WGVLLNSGIG EGAPRSFSAR ILGMVWAGFA MIIVASYTAN LAAFLVLDRP 
EERITGINDP RLRNPSDKFI YATVKQSSVD IYFRRQVELS TMYRHMEKHN YESAAEAIQA 
VRDNKLHAFI WDSAVLEFEA SQKCDLVTTG ELFFRSGFGI GMRKDSPWKQ NVSLSILKSH 
ENGFMEDLDK TWVRYQECDS RSNAPATLTF ENMAGVFMLV AGGIVAGIFL IFIEIAYKRH 
KDARRKQMQL AFAAVNVWRK NLQDRKSGRA EPDPKKKATF RAITSTLASS FKRRRSSKDT 
STGGGRGALQ NQKDTVLPRR AIEREEGQLQ LCSRHRES

Genular Protein ID: 3808919277

Symbol: A2AI16_MOUSE

Name: N/A

UniProtKB Accession Codes:

A2AI16

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 906
Mass: 101959
Checksum: 5DE227FF6E93B57F
Sequence:

MSTMHLLTFA LLFSCSFARA ACDPKIVNIG AVLSTRKHEQ MFREAVNQAN KRHGSWKIQL 
NATSVTHKPN AIQMALSVCE DLISSQVYAI LVSHPPTPND HFTPTPVSYT AGFYRIPVLG 
LTTRMSIYSD KSIHLSFLRT VPPYSHQSSV WFEMMRVYNW NHIILLVSDD HEGRAAQKRL 
ETLLEERESK SKKRNYENLD QLSYDNKRGP KAEKVLQFDP GTKNVTALLM EARDLEARVI 
ILSASEDDAA TVYRAAAMLN MTGSGYVWLV GEREISGNAL RYAPDGIIGL QLINGKNESA 
HISDAVGVVA QAVHELLEKE NITDPPRGCV GNTNIWKTGP LFKRVLMSSK YADGVTGRVE 
FNEDGDRKFA NYSIMNLQNR KLVQVGIYNG THVIPNDRKI IWPGGETEKP RGYQMSTRLK 
IVTIHQEPFV YVKPTMSDGT CKEEFTVNGD PVKKVICTGP NDTSPGSPRH TVPQCCYGFC 
VDLLIKLART MNFTYEVHLV ADGKFGTQER VNNSNKKEWN GMMGELLSGQ ADMIVAPLTI 
NNERAQYIEF SKPFKYQGLT ILVKKEIPRS TLDSFMQPFQ STLWLLVGLS VHVVAVMLYL 
LDRFSPFGRF KVNSEEEEED ALTLSSAMWF SWGVLLNSGI GEGAPRSFSA RILGMVWAGF 
AMIIVASYTA NLAAFLVLDR PEERITGIND PRLRNPSDKF IYATVKQSSV DIYFRRQVEL 
STMYRHMEKH NYESAAEAIQ AVRDNKLHAF IWDSAVLEFE ASQKCDLVTT GELFFRSGFG 
IGMRKDSPWK QNVSLSILKS HENGFMEDLD KTWVRYQECD SRSNAPATLT FENMAGVFML 
VAGGIVAGIF LIFIEIAYKR HKDARRKQMQ LAFAAVNVWR KNLQQYHPTD ITGPLNLSDP 
SVSTVV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Grin1

Associated with

Other Information

Cloning, expression and modulation of a mouse NMDA receptor subunit. PubMed ID: 1532151

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. PubMed ID: 8060614

Cloning and characterization of a novel NMDA receptor subunit NR3B: a dominant subunit that reduces calcium permeability. PubMed ID: 12008020

Specific assembly with the NMDA receptor 3B subunit controls surface expression and calcium permeability of NMDA receptors. PubMed ID: 14602821

GRINL1A colocalizes with N-methyl D-aspartate receptor NR1 subunit and reduces N-methyl D-aspartate toxicity. PubMed ID: 18849881

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome. PubMed ID: 23524343

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Database document:

PubMed ID: 1532151

PubMed ID: 19468303

PubMed ID: 15489334

PubMed ID: 8060614

PubMed ID: 12008020

PubMed ID: 14602821

PubMed ID: 18849881

PubMed ID: 21183079

PubMed ID: 23524343

PubMed ID: 19468303

PubMed ID: 21183079