Genular: Defining Cellular Identity and Function

Details for: Grin2d

Gene ID: 14814

Symbol: Grin2d

Ensembl ID: ENSMUSG00000002771

Description: glutamate receptor, ionotropic, NMDA2D (epsilon 4)

Associated with

Activation of nmda receptors and postsynaptic events
(R-MMU-442755)
Assembly and cell surface presentation of nmda receptors
(R-MMU-9609736)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Protein-protein interactions at synapses
(R-MMU-6794362)
Raf/map kinase cascade
(R-MMU-5673001)
Signal transduction
(R-MMU-162582)
Synaptic adhesion-like molecules
(R-MMU-8849932)
Transmission across chemical synapses
(R-MMU-112315)
Unblocking of nmda receptors, glutamate binding and activation
(R-MMU-438066)
Adult locomotory behavior
(GO:0008344)
Calcium ion transmembrane import into cytosol
(GO:0097553)
Cellular response to l-glutamate
(GO:1905232)
Detection of mechanical stimulus involved in sensory perception of pain
(GO:0050966)
Excitatory postsynaptic potential
(GO:0060079)
Glutamate-gated calcium ion channel activity
(GO:0022849)
Glutamate-gated receptor activity
(GO:0004970)
Glutamate binding
(GO:0016595)
Glutamatergic synapse
(GO:0098978)
Hippocampal mossy fiber to ca3 synapse
(GO:0098686)
Ionotropic glutamate receptor signaling pathway
(GO:0035235)
Ligand-gated monoatomic ion channel activity
(GO:0015276)
Ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
(GO:0099507)
Long-term synaptic potentiation
(GO:0060291)
Membrane
(GO:0016020)
Monoatomic cation channel activity
(GO:0005261)
Monoatomic cation transmembrane transport
(GO:0098655)
Monoatomic ion channel activity
(GO:0005216)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Nmda glutamate receptor activity
(GO:0004972)
Nmda selective glutamate receptor complex
(GO:0017146)
Plasma membrane
(GO:0005886)
Positive regulation of excitatory postsynaptic potential
(GO:2000463)
Positive regulation of synaptic transmission, glutamatergic
(GO:0051968)
Postsynaptic density membrane
(GO:0098839)
Postsynaptic membrane
(GO:0045211)
Presynaptic active zone membrane
(GO:0048787)
Regulation of monoatomic cation transmembrane transport
(GO:1904062)
Regulation of neuronal synaptic plasticity
(GO:0048168)
Regulation of sensory perception of pain
(GO:0051930)
Signaling receptor activity
(GO:0038023)
Startle response
(GO:0001964)
Synapse
(GO:0045202)
Synaptic transmission, glutamatergic
(GO:0035249)
Transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
(GO:1904315)
Voltage-gated monoatomic cation channel activity
(GO:0022843)

Other Information

Proteins

Glutamate receptor ionotropic, NMDA 2D

Genular Protein ID: 2649233965

Symbol: NMDE4_MOUSE

Name: Glutamate receptor ionotropic, NMDA 2D

UniProtKB Accession Codes:

Q03391 C9K0Z5

Database IDs:

Citations:

PubMed ID: 1385220

Title: Cloning and expression of the epsilon 4 subunit of the NMDA receptor channel.

PubMed ID: 1385220

DOI: 10.1016/0014-5793(92)81178-o

PubMed ID: 8774946

Title: Reduced spontaneous activity of mice defective in the epsilon 4 subunit of the NMDA receptor channel.

PubMed ID: 8774946

DOI: 10.1016/0169-328x(95)00107-4

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

Length: 1323
Mass: 142963
Checksum: 3DF8860D19677586
Sequence:

MRGAGGPRGP RGPAKMLLLL ALACASPFPE EVPGPGAAGG GTGGARPLNV ALVFSGPAYA 
AEAARLGPAV AAAVRSPGLD VRPVALVLNG SDPRSLVLQL CDLLSGLRVH GVVFEDDSRA 
PAVAPILDFL SAQTSLPIVA VHGGAALVLT PKEKGSTFLQ LGSSTEQQLQ VIFEVLEEYD 
WTSFVAVTTR APGHRAFLSY IEVLTDGSLV GWEHRGALTL DPGAGEAVLG AQLRSVSAQI 
RLLFCAREEA EPVFRAAEEA GLTGPGYVWF MVGPQLAGGG GSGVPGEPLL LPGGAPLPAG 
LFAVRSAGWR DDLARRVAAG VAVVARGAQA LLRDYGFLPE LGHDCRAQNR THRGESLHRY 
FMNITWDNRD YSFNEDGFLV NPSLVVISLT RDRTWEVVGS WEQQTLRLKY PLWSRYGRFL 
QPVDDTQHLT VATLEERPFV IVEPADPISG TCIRDSVPCR SQLNRTHSPP PDAPRPEKRC 
CKGFCIDILK RLAHTIGFSY DLYLVTNGKH GKKIDGVWNG MIGEVFYQRA DMAIGSLTIN 
EERSEIVDFS VPFVETGISV MVARSNGTVS PSAFLEPYSP AVWVMMFVMC LTVVAVTVFI 
FEYLSPVGYN RSLATGKRPG GSTFTIGKSI WLLWALVFNN SVPVENPRGT TSKIMVLVWA 
FFAVIFLASY TANLAAFMIQ EEYVDTVSGL SDRKFQRPQE QYPPLKFGTV PNGSTEKNIR 
SNYPDMHSYM VRYNQPRVEE ALTQLKAGKL DAFIYDAAVL NYMARKDEGC KLVTIGSGKV 
FATTGYGIAL HKGSRWKRPI DLALLQFLGD DEIEMLERLW LSGICHNDKI EVMSSKLDID 
NMAGVFYMLL VAMGLSLLVF AWEHLVYWRL RHCLGPTHRM DFLLAFSRGM YSCCSAEAAP 
PPAKPPPPPQ PLPSPAYPAA RPPPGPAPFV PRERAAADRW RRAKGTGPPG GAALADGFHR 
YYGPIEPQGL GLGEARAAPR GAAGRPLSPP TTQPPQKPPP SYFAIVREQE PAEPPAGAFP 
GFPSPPAPPA AAAAAVGPPL CRLAFEDESP PAPSRWPRSD PESQPLLGGG AGGPSAGAPT 
APPPRRAAPP PCAYLDLEPS PSDSEDSESL GGASLGGLEP WWFADFPYPY AERLGPPPGR 
YWSVDKLGGW RAGSWDYLPP RGGPAWHCRH CASLELLPPP RHLSCSHDGL DGGWWAPPPP 
PWAAGPPPRR RARCGCPRPH PHRPRASHRA PAAAPHHHRH RRAAGGWDLP PPAPTSRSLE 
DLSSCPRAAP TRRLTGPSRH ARRCPHAAHW GPPLPTASHR RHRGGDLGTR RGSAHFSSLE 
SEV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Grin2d

Associated with

Other Information

Cloning and expression of the epsilon 4 subunit of the NMDA receptor channel. PubMed ID: 1385220

Reduced spontaneous activity of mice defective in the epsilon 4 subunit of the NMDA receptor channel. PubMed ID: 8774946

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315

Database document:

PubMed ID: 1385220

PubMed ID: 8774946

PubMed ID: 21183079

PubMed ID: 24129315