Genular: Defining Cellular Identity and Function

Details for: Grm1

Gene ID: 14816

Symbol: Grm1

Ensembl ID: ENSMUSG00000019828

Description: glutamate receptor, metabotropic 1

Associated with

Class c/3 (metabotropic glutamate/pheromone receptors)
(R-MMU-420499)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Neurexins and neuroligins
(R-MMU-6794361)
Neuronal system
(R-MMU-112316)
Protein-protein interactions at synapses
(R-MMU-6794362)
Signaling by gpcr
(R-MMU-372790)
Adenylate cyclase inhibiting g protein-coupled glutamate receptor activity
(GO:0001640)
Axon
(GO:0030424)
Calcium-mediated signaling
(GO:0019722)
Cellular response to electrical stimulus
(GO:0071257)
Dendrite
(GO:0030425)
Dendritic spine
(GO:0043197)
Glutamate receptor activity
(GO:0008066)
Glutamatergic synapse
(GO:0098978)
G protein-coupled glutamate receptor signaling pathway
(GO:0007216)
G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
(GO:0098872)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
(GO:0099530)
G protein-coupled receptor dimeric complex
(GO:0038037)
G protein-coupled receptor homodimeric complex
(GO:0038038)
G protein-coupled receptor signaling pathway
(GO:0007186)
L-glutamate import across plasma membrane
(GO:0098712)
Locomotory behavior
(GO:0007626)
Membrane
(GO:0016020)
Neuronal cell body
(GO:0043025)
Neuron projection
(GO:0043005)
Neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
(GO:0099583)
Nuclear estrogen receptor binding
(GO:0030331)
Nucleus
(GO:0005634)
Phospholipase c-activating g protein-coupled glutamate receptor signaling pathway
(GO:0007206)
Plasma membrane
(GO:0005886)
Plc activating g protein-coupled glutamate receptor activity
(GO:0001639)
Positive regulation of mapk cascade
(GO:0043410)
Postsynaptic density
(GO:0014069)
Postsynaptic density membrane
(GO:0098839)
Postsynaptic membrane
(GO:0045211)
Presynaptic membrane
(GO:0042734)
Protein binding
(GO:0005515)
Regulation of sensory perception of pain
(GO:0051930)
Regulation of synaptic transmission, glutamatergic
(GO:0051966)
Schaffer collateral - ca1 synapse
(GO:0098685)
Sensory perception of pain
(GO:0019233)
Signal transduction
(GO:0007165)

Other Information

Proteins

Metabotropic glutamate receptor 1
Q3V0U2_MOUSE

Genular Protein ID: 1479426913

Symbol: GRM1_MOUSE

Name: Metabotropic glutamate receptor 1

UniProtKB Accession Codes:

P97772 Q6AXG4 Q9EPV6

Database IDs:

Citations:

PubMed ID: 10581402

Title: Cloning of novel splice variants of mouse mGluR1.

PubMed ID: 10581402

DOI: 10.1016/s0169-328x(99)00239-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 17296554

Title: Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity.

PubMed ID: 17296554

DOI: 10.1016/j.neuron.2007.01.019

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26427409

Title: A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects.

PubMed ID: 26427409

DOI: 10.1007/978-3-319-17121-0_24

Sequence Information:

Length: 1199
Mass: 133212
Checksum: FE5370AF160CC16E
Sequence:

MVRLLLIFFP MIFLEMSILP RMPDRKVLLA GASSQRSVAR MDGDVIIGAL FSVHHQPPAE 
KVPERKCGEI REQYGIQRVE AMFHTLDKIN ADPVLLPNIT LGSEIRDSCW HSSVALEQSI 
EFIRDSLISI RDEKDGLNRC LPDGQTLPPG RTKKPIAGVI GPGSSSVAIQ VQNLLQLFDI 
PQIAYSATSI DLSDKTLYKY FLRVVPSDTL QARAMLDIVK RYNWTYVSAV HTEGNYGESG 
MDAFKELAAQ EGLCIAHSDK IYSNAGEKSF DRLLRKLRER LPKARVVVCF CEGMTVRGLL 
SAMRRLGVVG EFSLIGSDGW ADRDEVIEGY EVEANGGITI KLQSPEVRSF DDYFLKLRLD 
TNTRNPWFPE FWQHRFQCRL PGHLLENPNF KKVCTGNESL EENYVQDSKM GFVINAIYAM 
AHGLQNMHHA LCPGYVGLCD AMKPIDGRKL LDFLIKSSFV GVSGEEVWFD EKGDAPGRYD 
IMNLQYTEAN RYDYVHVGTW HEGVLNIDDY KIQMNKSGMV RSVCSEPCLK GQIKVIRKGE 
VSCCWICTAC KENEFVQDEF TCRACDLGWW PNAELTGCEP ITIRYLEWSD IESIIAIAFS 
CLGILVTLFV TLIFVLYRDT PVVKSSSREL CYIILAGIFL GYVCPFTLIA KPTTTSCYLQ 
RLLVGLSSAM CYSALVTKTN RIARILAGSK KKICTRKPRF MSAWAQVIIA SILISVQLTL 
VVTLIIMEPP MPILSYPSIK EVYLICNTSN LGVVAPVGYN GLLIMSCTYY AFKTRNVPAN 
FNEAKYIAFT MYTTCIIWLA FVPIYFGSNY KIITTCFAVS LSVTVALGCM FTPKMYIIIA 
KPERNVRSAF TTSDVVRMHV GDGKLPCRSN TFLNIFRRKK PGAGNANSNG KSVSWSEPGG 
RQAPKGQHVW QRLSVHVKTN ETACNQTAVI KPLTKSYQGS GKSLTFSDAS TKTLYNVEEE 
DNTPSTHFSP PSSPSMVVHR RGPPVATTPP LPPHLSAEET PLFLADSVIP KGLPPPLPQQ 
QQQPPPQPPP QQPKSLMDQL QGVVTNFGSG IPDFHAVLAG PGTPGNGLRS LYPPPPPPQH 
LQMLPLQLST FREEPISPPG EDDDDDSSER FKLLQEFVYE REGNTEEDDL EEEEDLPAAS 
KLTPEDSPAL TPPSPFRDSV ASGSSVPSSP VSESVLCTPP NVTYASVILR DYKQSSSTL

Genular Protein ID: 887504667

Symbol: Q3V0U2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3V0U2

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 742
Mass: 81802
Checksum: CC66B666CF2E8A59
Sequence:

SFVGVSGEEV WFDEKGDAPG RYDIMNLQYT EANRYDYVHV GTWHEGVLNI DDYKIQMNKS 
GMVRSVCSEP CLKGQIKVIR KGEVSCCWIC TACKENEFVQ DEFTCRACDL GWWPNAELTG 
CEPITIRYLE WSDIESIIAI AFSCLGILVT LFVTLIFVLY RDTPVVKSSS RELCYIILAG 
IFLGYVCPFT LIAKPTTTSC YLQRLLVGLS SAMCYSALVT KTNRIARILA GSKKKICTRK 
PRFMSAWAQV IIASILISVQ LTLVVTLIIM EPPMPILSYP SIKEVYLICN TSNLGVVAPV 
GYNGLLIMSC TYYAFKTRNV PANFNEAKYI AFTMYTTCII WLAFVPIYFG SNYKIITTCF 
AVSLSVTVAL GCMFTPKMYI IIAKPERNVR SAFTTSDVVR MHVGDGKLPC RSNTFLNIFR 
RKKPGAGNAN SNGKSVSWSE PGGRQAPKGQ HVWQRLSVHV KTNETACNQT AVIKPLTKSY 
QGSGKSLTFS DASTKTLYNV EEEDNTPSTH FSPPSSPSMV VHRRGPPVAT TPPLPPHLSA 
EETPLFLADS VIPKGLPPPL PQQQQQPPPQ PPPQQPKSLM DQLQGVVTNF GSGIPDFHAV 
LAGPGTPGNG LRSLYPPPPP PQHLQMLPLQ LSTFREEPIS PPGEDDDDDS SERFKLLQEF 
VYEREGNTEE DDLEEEEDLP AASKLTPEDS PALTPPSPFR DSVASGSSVP SSPVSESVLC 
TPPNVTYASV ILRDYKQSSS TL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Grm1

Associated with

Other Information

Cloning of novel splice variants of mouse mGluR1. PubMed ID: 10581402

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Comprehensive identification of phosphorylation sites in postsynaptic density preparations. PubMed ID: 16452087

Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity. PubMed ID: 17296554

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects. PubMed ID: 26427409

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073