Details for: Gsc

Gene ID: 14836

Symbol: Gsc

Ensembl ID: ENSMUSG00000021095

Description: goosecoid homeobox

Associated with

  • Anatomical structure morphogenesis
    (GO:0009653)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Dorsal/ventral neural tube patterning
    (GO:0021904)
  • Ear development
    (GO:0043583)
  • Embryonic skeletal system morphogenesis
    (GO:0048704)
  • Forebrain development
    (GO:0030900)
  • Middle ear morphogenesis
    (GO:0042474)
  • Multicellular organism development
    (GO:0007275)
  • Muscle organ morphogenesis
    (GO:0048644)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Negative regulation of wnt signaling pathway
    (GO:0030178)
  • Neural crest cell fate specification
    (GO:0014036)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Protein binding
    (GO:0005515)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii-specific dna-binding transcription factor binding
    (GO:0061629)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Signal transduction involved in regulation of gene expression
    (GO:0023019)
  • Transcription regulator complex
    (GO:0005667)
  • Wnt signaling pathway
    (GO:0016055)

Other Information

Genular Protein ID: 2995685750

Symbol: GSC_MOUSE

Name: Homeobox protein goosecoid

UniProtKB Accession Codes:

Q02591

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 3 Ensembl 1 GO 21 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MGI 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 1352187

Title: Gastrulation in the mouse: the role of the homeobox gene goosecoid.

PubMed ID: 1352187

DOI: 10.1016/0092-8674(92)90632-m

PubMed ID: 9417125

Title: Negative autoregulation of the organizer-specific homeobox gene goosecoid.

PubMed ID: 9417125

DOI: 10.1074/jbc.273.1.627

PubMed ID: 14973294

Title: Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution.

PubMed ID: 14973294

DOI: 10.1242/dev.01017

PubMed ID: 24290375

Title: SAMS, a syndrome of short stature, auditory-canal atresia, mandibular hypoplasia, and skeletal abnormalities is a unique neurocristopathy caused by mutations in Goosecoid.

PubMed ID: 24290375

DOI: 10.1016/j.ajhg.2013.10.027

Sequence Information:

  • Length: 256
  • Mass: 27980
  • Checksum: 3639FB059AC3DB9E
  • Sequence:
    • MPASMFSIDN ILAARPRCKD AVLPVAPSAA APVVFPALHG DSLYGAGGGT SSDYGAFYPR 
PVAPGGAGLP AAVGSSRLGY NSYFYGQLHV QAAPVGPACC GAVPPLGAQQ CSCVPTPPGY 
EGPGSVLVSP VPHQMLPYMN VGTLSRTELQ LLNQLHCRRK RRHRTIFTDE QLEALENLFQ 
ETKYPDVGTR EQLARKVHLR EEKVEVWFKN RRAKWRRQKR SSSEESENAE KWNKTSSKAS 
PEKREEEGKS DLDSDS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.