Genular: Defining Cellular Identity and Function

Details for: Guca1a

Gene ID: 14913

Symbol: Guca1a

Ensembl ID: ENSMUSG00000023982

Description: guanylate cyclase activator 1a (retina)

Associated with

Inactivation, recovery and regulation of the phototransduction cascade
(R-MMU-2514859)
Sensory perception
(R-MMU-9709957)
The phototransduction cascade
(R-MMU-2514856)
Visual phototransduction
(R-MMU-2187338)
Calcium ion binding
(GO:0005509)
Calcium sensitive guanylate cyclase activator activity
(GO:0008048)
Cell projection
(GO:0042995)
Cone photoreceptor outer segment
(GO:0120199)
Guanylate cyclase regulator activity
(GO:0030249)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Photoreceptor inner segment
(GO:0001917)
Photoreceptor outer segment
(GO:0001750)
Phototransduction
(GO:0007602)
Positive regulation of cgmp-mediated signaling
(GO:0010753)
Positive regulation of guanylate cyclase activity
(GO:0031284)
Regulation of guanylate cyclase activity
(GO:0031282)
Response to stimulus
(GO:0050896)
Visual perception
(GO:0007601)

Other Information

Proteins

Guanylyl cyclase-activating protein 1

Genular Protein ID: 1935065681

Symbol: GUC1A_MOUSE

Name: Guanylyl cyclase-activating protein 1

UniProtKB Accession Codes:

P43081 Q8R0H3

Database IDs:

Citations:

PubMed ID: 7983048

Title: Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene.

PubMed ID: 7983048

DOI: 10.1016/s0021-9258(18)47393-0

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9620085

Title: The localization of guanylyl cyclase-activating proteins in the mammalian retina.

PubMed ID: 9620085

PubMed ID: 15961391

Title: Recoverin undergoes light-dependent intracellular translocation in rod photoreceptors.

PubMed ID: 15961391

DOI: 10.1074/jbc.m501789200

PubMed ID: 25673692

Title: Regulation of mammalian cone phototransduction by recoverin and rhodopsin kinase.

PubMed ID: 25673692

DOI: 10.1074/jbc.m115.639591

PubMed ID: 29435986

Title: Role of recoverin in rod photoreceptor light adaptation.

PubMed ID: 29435986

DOI: 10.1113/jp275779

Sequence Information:

Length: 202
Mass: 22986
Checksum: EC76CBF7C518C76B
Sequence:

MGNIMEGKSV EELSSTECHQ WYKKFMTECP SGQLTLYEFR QFFGLKNLSP SASQYVEQMF 
ETFDFNKDGY IDFMEYVAAL SLVLKGKVEQ KLRWYFKLYD VDGNGCIDRD ELLTIIRAIR 
TINPWSDSSM SAEEFTDTVF AKIDINGDGE LSLEEFMEGV QKDQMLLDTL TRSLDLTGIV 
RRLQNGEHEE AGTGDLAAEA AG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Guca1a

Associated with

Other Information

Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene. PubMed ID: 7983048

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The localization of guanylyl cyclase-activating proteins in the mammalian retina. PubMed ID: 9620085

Recoverin undergoes light-dependent intracellular translocation in rod photoreceptors. PubMed ID: 15961391

Regulation of mammalian cone phototransduction by recoverin and rhodopsin kinase. PubMed ID: 25673692

Role of recoverin in rod photoreceptor light adaptation. PubMed ID: 29435986