Details for: Gzma

Gene ID: 14938

Symbol: Gzma

Ensembl ID: ENSMUSG00000023132

Description: granzyme A

Associated with

Other Information

Genular Protein ID: 1698842133

Symbol: GRAA_MOUSE

Name: Granzyme A

UniProtKB Accession Codes:

P11032 P15118

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EC 2 EMBL 16 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 17 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 MEROPS 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 3 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 2 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 2976140

Title: cDNA clones from autocrine thymic lymphoma cells encode two mitogenic proteins, a serine protease and a truncated T-cell receptor beta-chain.

PubMed ID: 2976140

PubMed ID: 1639378

Title: Organization of the gene encoding the mouse T-cell-specific serine proteinase 'granzyme A'.

PubMed ID: 1639378

DOI: 10.1016/0888-7543(92)90117-b

PubMed ID: 1460043

Title: Genomic organization of the mouse granzyme A gene. Two mRNAs encode the same mature granzyme A with different leader peptides.

PubMed ID: 1460043

DOI: 10.1016/s0021-9258(19)74067-8

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3292396

Title: Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation.

PubMed ID: 3292396

DOI: 10.1111/j.1600-065x.1988.tb00749.x

PubMed ID: 2422755

Title: Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte.

PubMed ID: 2422755

DOI: 10.1126/science.2422755

PubMed ID: 3555842

Title: A family of serine esterases in lytic granules of cytolytic T lymphocytes.

PubMed ID: 3555842

DOI: 10.1016/0092-8674(87)90544-7

PubMed ID: 3533635

Title: Identification of granzyme A isolated from cytotoxic T-lymphocyte-granules as one of the proteases encoded by CTL-specific genes.

PubMed ID: 3533635

DOI: 10.1016/0014-5793(86)81537-x

PubMed ID: 3260181

Title: Induction of T cell serine proteinase 1 (TSP-1)-specific mRNA in mouse T lymphocytes.

PubMed ID: 3260181

DOI: 10.1002/eji.1830180605

Sequence Information:

  • Length: 260
  • Mass: 28599
  • Checksum: 7705352F08DEED8D
  • Sequence:
    • MRNASGPRGP SLATLLFLLL IPEGGCERII GGDTVVPHSR PYMALLKLSS NTICAGALIE 
KNWVLTAAHC NVGKRSKFIL GAHSINKEPE QQILTVKKAF PYPCYDEYTR EGDLQLVRLK 
KKATVNRNVA ILHLPKKGDD VKPGTRCRVA GWGRFGNKSA PSETLREVNI TVIDRKICND 
EKHYNFHPVI GLNMICAGDL RGGKDSCNGD SGSPLLCDGI LRGITSFGGE KCGDRRWPGV 
YTFLSDKHLN WIKKIMKGSV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.