Details for: CTNNA2

Gene ID: 1496

Symbol: CTNNA2

Ensembl ID: ENSG00000066032

Description: catenin alpha 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 52.0195
    Cell Significance Index: 7561.6500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.6364
    Cell Significance Index: -21.0900
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 9.2688
    Cell Significance Index: 129.6100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 8.0091
    Cell Significance Index: 492.2800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 7.6193
    Cell Significance Index: 182.7300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 4.4868
    Cell Significance Index: 198.4600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 4.4019
    Cell Significance Index: 166.6900
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 4.1596
    Cell Significance Index: 43.3300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 3.9941
    Cell Significance Index: 268.5700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 3.9423
    Cell Significance Index: 1414.0200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 3.9356
    Cell Significance Index: 2721.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.8088
    Cell Significance Index: 764.0400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 3.1044
    Cell Significance Index: 88.5900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.2577
    Cell Significance Index: 126.6900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.8727
    Cell Significance Index: 3526.0200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.7633
    Cell Significance Index: 38.6100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.2506
    Cell Significance Index: 1925.2600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.9761
    Cell Significance Index: 619.9000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.9332
    Cell Significance Index: 15.9900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.8723
    Cell Significance Index: 1186.1500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3794
    Cell Significance Index: 342.5600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1684
    Cell Significance Index: 32.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0546
    Cell Significance Index: 100.6700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.2011
    Cell Significance Index: -91.2600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.2084
    Cell Significance Index: -154.3600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.2362
    Cell Significance Index: -173.1700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.2817
    Cell Significance Index: -153.8500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.2903
    Cell Significance Index: -163.7000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.3261
    Cell Significance Index: -203.6700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.4083
    Cell Significance Index: -81.0300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.4178
    Cell Significance Index: -5.2100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4839
    Cell Significance Index: -139.2400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.6258
    Cell Significance Index: -17.4900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.6333
    Cell Significance Index: -6.9000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.6793
    Cell Significance Index: -110.4800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.7335
    Cell Significance Index: -31.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.8250
    Cell Significance Index: -148.7200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.8445
    Cell Significance Index: -38.2800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.8621
    Cell Significance Index: -181.5800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.8903
    Cell Significance Index: -152.0200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.8938
    Cell Significance Index: -114.5800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.9051
    Cell Significance Index: -89.5300
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.0029
    Cell Significance Index: -11.7000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -1.0481
    Cell Significance Index: -143.9300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -1.1756
    Cell Significance Index: -41.3100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -1.1786
    Cell Significance Index: -144.9200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -1.1829
    Cell Significance Index: -128.6600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.1945
    Cell Significance Index: -23.6200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -1.2730
    Cell Significance Index: -130.0400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.2766
    Cell Significance Index: -78.2700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -1.3523
    Cell Significance Index: -157.5900
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.3564
    Cell Significance Index: -17.1200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.4475
    Cell Significance Index: -150.7200
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -1.4528
    Cell Significance Index: -19.3800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -1.6909
    Cell Significance Index: -193.7200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -2.0769
    Cell Significance Index: -159.3800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -2.1301
    Cell Significance Index: -147.3100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -2.2708
    Cell Significance Index: -32.5200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -2.3152
    Cell Significance Index: -40.0300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -2.3390
    Cell Significance Index: -76.5800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -2.5574
    Cell Significance Index: -153.5300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -2.6368
    Cell Significance Index: -83.9800
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -2.7925
    Cell Significance Index: -26.5700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -2.8101
    Cell Significance Index: -147.5400
  • Cell Name: neuron (CL0000540)
    Fold Change: -2.8267
    Cell Significance Index: -26.8000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -2.9651
    Cell Significance Index: -20.0900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -2.9804
    Cell Significance Index: -187.8500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -3.0043
    Cell Significance Index: -156.4900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -3.0456
    Cell Significance Index: -61.1500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -3.0972
    Cell Significance Index: -108.5000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -3.2367
    Cell Significance Index: -68.7000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -3.3890
    Cell Significance Index: -159.2800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -3.4357
    Cell Significance Index: -160.1900
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: -3.4771
    Cell Significance Index: -27.2700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -3.4817
    Cell Significance Index: -110.1200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -3.5119
    Cell Significance Index: -75.8800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -3.5598
    Cell Significance Index: -102.5700
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -3.6374
    Cell Significance Index: -41.6300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -3.7199
    Cell Significance Index: -95.6200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -4.0540
    Cell Significance Index: -101.1300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -4.0986
    Cell Significance Index: -102.4600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -4.1577
    Cell Significance Index: -215.9800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -4.2167
    Cell Significance Index: -53.2100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -4.2899
    Cell Significance Index: -157.4800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -4.3319
    Cell Significance Index: -90.4100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -4.4248
    Cell Significance Index: -86.3600
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -4.8047
    Cell Significance Index: -62.3100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -5.1012
    Cell Significance Index: -163.3900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -5.1950
    Cell Significance Index: -180.5300
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: -5.4147
    Cell Significance Index: -60.1700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -5.5920
    Cell Significance Index: -117.0500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -5.6829
    Cell Significance Index: -162.9100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -5.8356
    Cell Significance Index: -155.8200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -6.1464
    Cell Significance Index: -161.6200
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -6.1726
    Cell Significance Index: -50.9500
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -6.1864
    Cell Significance Index: -121.7600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -6.1967
    Cell Significance Index: -182.5200
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -6.2041
    Cell Significance Index: -82.7000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -6.2077
    Cell Significance Index: -158.1600
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -6.2729
    Cell Significance Index: -127.6400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CTNNA2 is a cytoskeletal protein that belongs to the catenin family, which consists of three main members: alpha, beta, and gamma catenins. The alpha catenins are characterized by their ability to bind to the cytoskeletal protein actin, while also interacting with beta-catenin, a key component of the Wnt signaling pathway. CTNNA2 is specifically expressed in cells derived from the nervous system, including neurons, astrocytes, and glial cells. Its expression is also observed in epithelial cells, particularly those derived from the lung and retina. **Pathways and Functions** CTNNA2 is involved in several key cellular pathways, including: 1. **Actin Cytoskeleton Organization**: CTNNA2 interacts with actin to regulate cytoskeleton organization and dynamics. 2. **Adherens Junction Formation**: CTNNA2 plays a crucial role in the formation and maintenance of adherens junctions, which are essential for maintaining tissue structure and organization. 3. **Neuronal Migration and Axonogenesis**: CTNNA2 regulates neuronal migration, axonogenesis, and synapse structural plasticity, essential for neuronal development and function. 4. **Wnt Signaling Pathway**: CTNNA2 interacts with beta-catenin, a key component of the Wnt signaling pathway, to regulate cell-cell adhesion and cell migration. 5. **Cytoskeleton Organization**: CTNNA2 regulates the organization of the cytoskeleton, including the formation of actin filaments and microtubules. **Clinical Significance** Dysregulation of CTNNA2 has been implicated in various neurological disorders, including: 1. **Neurodevelopmental Disorders**: CTNNA2 mutations have been associated with neurodevelopmental disorders, such as autism spectrum disorder and intellectual disability. 2. **Neurodegenerative Diseases**: CTNNA2 has been implicated in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 3. **Cancer**: CTNNA2 has been identified as a potential oncogene, with its expression being upregulated in certain types of cancer, including breast and lung cancer. 4. **Neurological Disorders**: CTNNA2 has been implicated in various neurological disorders, including epilepsy, schizophrenia, and bipolar disorder. In conclusion, CTNNA2 is a critical gene involved in various cellular processes, including cell-cell adhesion, cytoskeleton organization, and neuronal development. Its dysregulation has been implicated in various neurological disorders, highlighting the importance of further research into the role of CTNNA2 in human health and disease.

Genular Protein ID: 3222354030

Symbol: CTNA2_HUMAN

Name: Catenin alpha-2

UniProtKB Accession Codes:

P26232 B3KXE5 B7Z2W7 B7Z352 B7Z898 Q4ZFW1 Q53R26 Q53R33 Q53T67 Q53T71 Q53TM8 Q7Z3L1 Q7Z3Y0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CPTAC 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 20 EMDB 1 Ensembl 6 ExpressionAtlas 1 GO 22 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 1 RefSeq 10 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8432524

Title: Characterization and chromosomal assignment of a human cDNA encoding a protein related to the murine 102-kDa cadherin-associated protein (alpha-catenin).

PubMed ID: 8432524

DOI: 10.1006/geno.1993.1004

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16182284

Title: Nuclear translocation of alphaN-catenin by the novel zinc finger transcriptional repressor ZASC1.

PubMed ID: 16182284

DOI: 10.1016/j.yexcr.2005.06.018

PubMed ID: 18163523

Title: Regulation of a novel alphaN-catenin splice variant in schizophrenic smokers.

PubMed ID: 18163523

DOI: 10.1002/ajmg.b.30679

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 30013181

Title: Biallelic loss of human CTNNA2, encoding alphaN-catenin, leads to ARP2/3 complex overactivity and disordered cortical neuronal migration.

PubMed ID: 30013181

DOI: 10.1038/s41588-018-0166-0

Sequence Information:

  • Length: 953
  • Mass: 105313
  • Checksum: 5FC88907B37E8A6C
  • Sequence:
    • MTSATSPIIL KWDPKSLEIR TLTVERLLEP LVTQVTTLVN TSNKGPSGKK KGRSKKAHVL 
AASVEQATQN FLEKGEQIAK ESQDLKEELV AAVEDVRKQG ETMRIASSEF ADDPCSSVKR 
GTMVRAARAL LSAVTRLLIL ADMADVMRLL SHLKIVEEAL EAVKNATNEQ DLANRFKEFG 
KEMVKLNYVA ARRQQELKDP HCRDEMAAAR GALKKNATML YTASQAFLRH PDVAATRANR 
DYVFKQVQEA IAGISNAAQA TSPTDEAKGH TGIGELAAAL NEFDNKIILD PMTFSEARFR 
PSLEERLESI ISGAALMADS SCTRDDRRER IVAECNAVRQ ALQDLLSEYM NNTGRKEKGD 
PLNIAIDKMT KKTRDLRRQL RKAVMDHISD SFLETNVPLL VLIEAAKSGN EKEVKEYAQV 
FREHANKLVE VANLACSISN NEEGVKLVRM AATQIDSLCP QVINAALTLA ARPQSKVAQD 
NMDVFKDQWE KQVRVLTEAV DDITSVDDFL SVSENHILED VNKCVIALQE GDVDTLDRTA 
GAIRGRAARV IHIINAEMEN YEAGVYTEKV LEATKLLSET VMPRFAEQVE VAIEALSANV 
PQPFEENEFI DASRLVYDGV RDIRKAVLMI RTPEELEDDS DFEQEDYDVR SRTSVQTEDD 
QLIAGQSARA IMAQLPQEEK AKIAEQVEIF HQEKSKLDAE VAKWDDSGND IIVLAKQMCM 
IMMEMTDFTR GKGPLKNTSD VINAAKKIAE AGSRMDKLAR AVADQCPDSA CKQDLLAYLQ 
RIALYCHQLN ICSKVKAEVQ NLGGELIVSG TGVQSTFTTF YEVDCDVIDG GRASQLSTHL 
PTCAEGAPIG SGSSDSSMLD SATSLIQAAK NLMNAVVLTV KASYVASTKY QKVYGTAAVN 
SPVVSWKMKA PEKKPLVKRE KPEEFQTRVR RGSQKKHISP VQALSEFKAM DSF

Genular Protein ID: 3050901922

Symbol: F6KRI5_HUMAN

Name: N/A

UniProtKB Accession Codes:

F6KRI5

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 ExpressionAtlas 1 GO 11 Gene3D 2 HOGENOM 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 Pfam 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 21708131

Title: Bidirectional transcription from human LRRTM2/CTNNA1 and LRRTM1/CTNNA2 gene loci leads to expression of N-terminally truncated CTNNA1 and CTNNA2 isoforms.

PubMed ID: 21708131

DOI: 10.1016/j.bbrc.2011.06.085

Sequence Information:

  • Length: 537
  • Mass: 59868
  • Checksum: 71B24F41F0B4D6FB
  • Sequence:
    • MTKKTRDLRR QLRKAVMDHI SDSFLETNVP LLVLIEAAKS GNEKEVKEYA QVFREHANKL 
VEVANLACSI SNNEEGVKLV RMAATQIDSL CPQVINAALT LAARPQSKVA QDNMDVFKDQ 
WEKQVRVLTE AVDDITSVDD FLSVSENHIL EDVNKCVIAL QEGDVDTLDR TAGAIRGRAA 
RVIHIINAEM ENYEAGVYTE KVLEATKLLS ETVMPRFAEQ VEVAIEALSA NVPQPFEENE 
FIDASRLVYD GVRDIRKAVL MIRTPEELED DSDFEQEDYD VRSRTSVQTE DDQLIAGQSA 
RAIMAQLPQE EKAKIAEQVE IFHQEKSKLD AEVAKWDDSG NDIIVLAKQM CMIMMEMTDF 
TRGKGPLKNT SDVINAAKKI AEAGSRMDKL ARAVADQCPD SACKQDLLAY LQRIALYCHQ 
LNICSKVKAE VQNLGGELIV SGLDSATSLI QAAKNLMNAV VLTVKASYVA STKYQKVYGT 
AAVNSPVVSW KMKAPEKKPL VKREKPEEFQ TRVRRGSQKK HISPVQALSE FKAMDSF

Genular Protein ID: 3029910206

Symbol: Q49AD3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q49AD3

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 11 Gene3D 2 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 687
  • Mass: 76384
  • Checksum: C7FB874BFAFCA16D
  • Sequence:
    • MLYTASQAFL RHPDVAATRA NRDYVFKQVQ EAIAGISNAA QATSPTDEAK GHTGIGELAA 
ALNEFDNKII LDPMTFSEAR FRQSLEERLE SIISGAALMA DSSCTRDDRR ERIVAECNAV 
RQALQDLLSE YMNNTGRKEK GDPLNIAIDK MTKKTRDLRR QLRKAVMDHI SDSFLETNVP 
LLVLIEAAKS GNEKEVKEYA QVFREHANKL VEVANLACSI SNNEEGVKLV RMAATQIDSL 
CPQVINAALT LAARPQSKVA QDNMDVFKDQ WEKQVRVLTE AVDDITSVDD FLSVSENHIL 
EDVNKCVIAL QEGDVDTLDR TAGAIRGRAA RVIHIINAEM ENYEAGVYTE KVLEATKLLS 
ETVMPRFAEQ VEVAIEALSA NVPQPFEENE FIDASRLVYD GVRDIRKAVL MIRTPEELED 
DSDFEQEDYD VRSRTSVQTE DDQLIAGQSA RAIMAQLPQE EKAKIAEQVE IFHQEKSKLD 
AEVAKWDDSG NDIIVLAKQM CMIMMEMTDF TRGKGPLKNT SDVINAAKKI AEAGSRMDKL 
ARAVADQCPD SACKQDLLAY LQRIALYCHQ LNICSKVKAE VQNLGGELIV SGLDSATSLI 
QAAKNLMNAV VLTVKASYVA STKYQKVYGT AAVNSPVVSW KMKAPEKKPL VKREKPEEFQ 
TRVRRGSQKK HISPVQALSE FKAMDSF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.