Details for: H2 M9

Gene ID: 14997

Symbol: H2 M9

Ensembl ID: ENSMUSG00000067201

Description: histocompatibility 2, M region locus 9

Associated with

  • Adaptive immune system
    (R-MMU-1280218)
  • Antigen presentation: folding, assembly and peptide loading of class i mhc
    (R-MMU-983170)
  • Antigen processing-cross presentation
    (R-MMU-1236975)
  • Class i mhc mediated antigen processing & presentation
    (R-MMU-983169)
  • Dap12 interactions
    (R-MMU-2172127)
  • Endosomal/vacuolar pathway
    (R-MMU-1236977)
  • Er-phagosome pathway
    (R-MMU-1236974)
  • Immune system
    (R-MMU-168256)
  • Immunoregulatory interactions between a lymphoid and a non-lymphoid cell
    (R-MMU-198933)
  • Innate immune system
    (R-MMU-168249)
  • Neutrophil degranulation
    (R-MMU-6798695)
  • Adaptive immune response
    (GO:0002250)
  • Antibacterial humoral response
    (GO:0019731)
  • Antigen processing and presentation of endogenous peptide antigen via mhc class ib
    (GO:0002476)
  • Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway, tap-independent
    (GO:0002486)
  • Antigen processing and presentation of exogenous peptide antigen via mhc class ib
    (GO:0002477)
  • Beta-2-microglobulin binding
    (GO:0030881)
  • Cd8-positive, alpha-beta t cell activation
    (GO:0036037)
  • Cell surface
    (GO:0009986)
  • Defense response to gram-positive bacterium
    (GO:0050830)
  • Endoplasmic reticulum
    (GO:0005783)
  • External side of plasma membrane
    (GO:0009897)
  • Extracellular space
    (GO:0005615)
  • Golgi apparatus
    (GO:0005794)
  • Immune response
    (GO:0006955)
  • Mhc class ib protein complex
    (GO:0032398)
  • Mhc class i protein binding
    (GO:0042288)
  • Mhc class i protein complex
    (GO:0042612)
  • Natural killer cell lectin-like receptor binding
    (GO:0046703)
  • Natural killer cell tolerance induction
    (GO:0002519)
  • Negative regulation of natural killer cell activation
    (GO:0032815)
  • Negative regulation of natural killer cell mediated cytotoxicity
    (GO:0045953)
  • Negative regulation of t cell proliferation
    (GO:0042130)
  • Peptide antigen binding
    (GO:0042605)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of antibody-dependent cellular cytotoxicity
    (GO:0001815)
  • Positive regulation of cd8-positive, alpha-beta t cell activation
    (GO:2001187)
  • Positive regulation of cd8-positive, alpha-beta t cell proliferation
    (GO:2000566)
  • Positive regulation of immunoglobulin production
    (GO:0002639)
  • Positive regulation of interleukin-4 production
    (GO:0032753)
  • Positive regulation of interleukin-13 production
    (GO:0032736)
  • Positive regulation of natural killer cell activation
    (GO:0032816)
  • Positive regulation of natural killer cell cytokine production
    (GO:0002729)
  • Positive regulation of natural killer cell mediated cytotoxicity
    (GO:0045954)
  • Positive regulation of natural killer cell mediated immunity
    (GO:0002717)
  • Positive regulation of natural killer cell proliferation
    (GO:0032819)
  • Positive regulation of t cell mediated cytotoxicity
    (GO:0001916)
  • Positive regulation of trail production
    (GO:0032759)
  • Positive regulation of tumor necrosis factor production
    (GO:0032760)
  • Protection from natural killer cell mediated cytotoxicity
    (GO:0042270)
  • Protein-folding chaperone binding
    (GO:0051087)
  • Regulation of natural killer cell mediated immunity
    (GO:0002715)
  • Signaling receptor binding
    (GO:0005102)
  • T cell receptor binding
    (GO:0042608)

Other Information

Genular Protein ID: 1889713065

Symbol: O19442_MOUSE

Name: N/A

UniProtKB Accession Codes:

O19442

Database IDs:

AGR 1 ARBA 9 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 40 Gene3D 2 GeneTree 1 HOGENOM 1 InterPro 9 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PaxDb 1 Pfam 2 Proteomes 2 Reactome 6 RefSeq 1 RuleBase 1 SAM 2 SMART 1 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9435345

Title: Characterization of two class I genes from the H2-M region: evidence for a new subfamily.

PubMed ID: 9435345

DOI: 10.1007/s002510050356

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 342
  • Mass: 39881
  • Checksum: AB5B6EC1DB4D93BD
  • Sequence:
    • MKNFESQPLL LLFMVTLVIA KHPNGSHTLR FVSTFLSWPR HLELQFIFLI YVDETQIMGF 
NSISESQRME SRVPWLNELN AEFWELATQD VLKEKSFVTG IMNKLLHIYN DSMTGYHIIQ 
ETYGCQVKQR TYFSHAFMEL LFDTHDYITL NEDLQTWRAV GKAAEIVKEE WEKINLVKSS 
KSFLLGACVE GLLQYLNFGK KYLLRTDTPK IHMTYKIRPD RKITLRCWAF NFYPPEITLT 
WQRDGSNQTQ DMEVIEIRPS GDGTFQKWAA VVVSSGEEHR YTCHVNHEGL SEPVTLRWDP 
PEPTIPFLPM IIALVLGALL MGSVMTFLIW KRRTRGKKGS WS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.