Details for: AANAT
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: erythrocyte (CL0000232)
Fold Change: 3.22
Marker Score: 1,784 - Cell Name: blood vessel endothelial cell (CL0000071)
Fold Change: 2.21
Marker Score: 2,227 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.99
Marker Score: 1,040 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.61
Marker Score: 1,173 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 1.59
Marker Score: 3,281 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.27
Marker Score: 858 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.15
Marker Score: 4,820 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.14
Marker Score: 2,152 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.06
Marker Score: 676 - Cell Name: goblet cell (CL0000160)
Fold Change: 1.05
Marker Score: 6,949 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,832 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,057 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 511 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 464 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,409 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,413 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.94
Marker Score: 391 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5,353 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.94
Marker Score: 375 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.92
Marker Score: 14,454 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2,742 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.91
Marker Score: 327 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.88
Marker Score: 405 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,292 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.84
Marker Score: 1,705 - Cell Name: mast cell (CL0000097)
Fold Change: 0.83
Marker Score: 484 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.83
Marker Score: 437 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.78
Marker Score: 596 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,264 - Cell Name: brush cell (CL0002204)
Fold Change: 0.78
Marker Score: 710 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 398 - Cell Name: pericyte (CL0000669)
Fold Change: 0.72
Marker Score: 423 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.72
Marker Score: 227 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7
Marker Score: 179 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.65
Marker Score: 210 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.58
Marker Score: 373 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.56
Marker Score: 236 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 450 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.55
Marker Score: 174 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.55
Marker Score: 361 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.49
Marker Score: 129 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 0.46
Marker Score: 1,356 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.46
Marker Score: 145 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.46
Marker Score: 277 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.4
Marker Score: 383 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.36
Marker Score: 855 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.33
Marker Score: 156 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.3
Marker Score: 302 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 0.3
Marker Score: 885 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.29
Marker Score: 130 - Cell Name: macrophage (CL0000235)
Fold Change: 0.28
Marker Score: 306 - Cell Name: podocyte (CL0000653)
Fold Change: 0.24
Marker Score: 88 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 0.23
Marker Score: 87 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.22
Marker Score: 64 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.22
Marker Score: 74 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.22
Marker Score: 56 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.19
Marker Score: 86 - Cell Name: dendritic cell (CL0000451)
Fold Change: 0.19
Marker Score: 132 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.18
Marker Score: 104 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 0.18
Marker Score: 126 - Cell Name: monocyte (CL0000576)
Fold Change: 0.18
Marker Score: 234 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.18
Marker Score: 105 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.17
Marker Score: 43 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.17
Marker Score: 49 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.16
Marker Score: 58 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.16
Marker Score: 666 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0.14
Marker Score: 1,164 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.13
Marker Score: 61 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.13
Marker Score: 130 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.13
Marker Score: 231 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.12
Marker Score: 50 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.12
Marker Score: 1,198 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.11
Marker Score: 169 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.1
Marker Score: 290 - Cell Name: Mueller cell (CL0000636)
Fold Change: 0.1
Marker Score: 139 - Cell Name: neuron (CL0000540)
Fold Change: 0.1
Marker Score: 393 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.1
Marker Score: 83 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.08
Marker Score: 171 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.08
Marker Score: 34 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.08
Marker Score: 133 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.08
Marker Score: 18 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.08
Marker Score: 61 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.08
Marker Score: 93 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.08
Marker Score: 18 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.08
Marker Score: 70 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 0.07
Marker Score: 42 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.07
Marker Score: 4,388 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.07
Marker Score: 18 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 0.07
Marker Score: 18 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.07
Marker Score: 2,592 - Cell Name: plasma cell (CL0000786)
Fold Change: 0.07
Marker Score: 77 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 0.07
Marker Score: 193 - Cell Name: B cell (CL0000236)
Fold Change: 0.07
Marker Score: 64 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.07
Marker Score: 16 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 0.07
Marker Score: 62 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.06
Marker Score: 34 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.06
Marker Score: 3,561 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.06
Marker Score: 79 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.06
Marker Score: 15 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.06
Marker Score: 17
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1782899179
Symbol: SNAT_HUMAN
Name: Serotonin N-acetyltransferase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8661026
Title: The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression.
PubMed ID: 8661026
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11313340
Title: cAMP regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation.
PubMed ID: 11313340
PubMed ID: 11427721
Title: Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis.
PubMed ID: 11427721
PubMed ID: 18212399
Title: Role of melatonin in upper gastrointestinal tract.
PubMed ID: 18212399
PubMed ID: 12736803
Title: Significant association of the arylalkylamine N-acetyltransferase (AA-NAT) gene with delayed sleep phase syndrome.
PubMed ID: 12736803
Sequence Information:
- Length: 207
- Mass: 23344
- Checksum: 7476612F3661E0D5
- Sequence:
MSTQSTHPLK PEAPRLPPGI PESPSCQRRH TLPASEFRCL TPEDAVSAFE IEREAFISVL GVCPLYLDEI RHFLTLCPEL SLGWFEEGCL VAFIIGSLWD KERLMQESLT LHRSGGHIAH LHVLAVHRAF RQQGRGPILL WRYLHHLGSQ PAVRRAALMC EDALVPFYER FSFHAVGPCA ITVGSLTFME LHCSLRGHPF LRRNSGC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.