Details for: CTNND1

Gene ID: 1500

Symbol: CTNND1

Ensembl ID: ENSG00000198561

Description: catenin delta 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 429.5857
    Cell Significance Index: -66.8200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 260.2473
    Cell Significance Index: -66.0100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 149.0724
    Cell Significance Index: -61.4100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 147.6099
    Cell Significance Index: -69.6900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 139.0253
    Cell Significance Index: -56.4800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 125.6062
    Cell Significance Index: -64.6100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 58.8116
    Cell Significance Index: -56.1500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 55.1358
    Cell Significance Index: -67.9800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 25.1712
    Cell Significance Index: -67.4300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 17.2730
    Cell Significance Index: -68.1600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 15.4026
    Cell Significance Index: -33.7100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 5.0445
    Cell Significance Index: 262.7600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 3.4745
    Cell Significance Index: 92.7800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 3.3783
    Cell Significance Index: 97.3400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.5653
    Cell Significance Index: 133.2600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.5585
    Cell Significance Index: 513.2400
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 2.5121
    Cell Significance Index: 15.4600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.5060
    Cell Significance Index: 451.7500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.4563
    Cell Significance Index: 302.0200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.3013
    Cell Significance Index: 62.6400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.0888
    Cell Significance Index: 19.2400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.9895
    Cell Significance Index: 111.6400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.8272
    Cell Significance Index: 112.3100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.5823
    Cell Significance Index: 34.2800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.5662
    Cell Significance Index: 43.7700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.5321
    Cell Significance Index: 117.5700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.5022
    Cell Significance Index: 148.6000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.2546
    Cell Significance Index: 248.9900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2028
    Cell Significance Index: 1086.0700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.1551
    Cell Significance Index: 125.6400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.0767
    Cell Significance Index: 386.2000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.0721
    Cell Significance Index: 15.4200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9347
    Cell Significance Index: 510.4700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.9124
    Cell Significance Index: 42.8800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.8735
    Cell Significance Index: 30.7000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.8698
    Cell Significance Index: 384.5600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.7762
    Cell Significance Index: 36.1900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5819
    Cell Significance Index: 43.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5371
    Cell Significance Index: 73.7600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5076
    Cell Significance Index: 351.0600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4240
    Cell Significance Index: 80.6900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.3648
    Cell Significance Index: 7.7700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3495
    Cell Significance Index: 24.7200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.3211
    Cell Significance Index: 7.7000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.2599
    Cell Significance Index: 1.5700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1890
    Cell Significance Index: 24.2300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1612
    Cell Significance Index: 20.8300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0057
    Cell Significance Index: 0.0900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0075
    Cell Significance Index: -5.5100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0111
    Cell Significance Index: -1.8900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0274
    Cell Significance Index: -51.6100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0337
    Cell Significance Index: -62.0900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0397
    Cell Significance Index: -30.0800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0470
    Cell Significance Index: -72.3800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0513
    Cell Significance Index: -1.3500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0592
    Cell Significance Index: -80.5100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0644
    Cell Significance Index: -47.6700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0762
    Cell Significance Index: -7.7800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0867
    Cell Significance Index: -55.0600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1168
    Cell Significance Index: -65.8700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1255
    Cell Significance Index: -78.3500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1383
    Cell Significance Index: -62.7700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2010
    Cell Significance Index: -57.8400
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2190
    Cell Significance Index: -5.0600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2764
    Cell Significance Index: -12.5300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3597
    Cell Significance Index: -41.9200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3630
    Cell Significance Index: -76.4500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3892
    Cell Significance Index: -44.5900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3892
    Cell Significance Index: -5.3100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3987
    Cell Significance Index: -57.9600
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -0.4649
    Cell Significance Index: -4.6900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.4979
    Cell Significance Index: -58.7200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.5371
    Cell Significance Index: -4.3800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.5507
    Cell Significance Index: -24.3600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.5511
    Cell Significance Index: -8.3700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5985
    Cell Significance Index: -14.9600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6553
    Cell Significance Index: -68.2300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6886
    Cell Significance Index: -22.0600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6893
    Cell Significance Index: -54.5900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6898
    Cell Significance Index: -26.1200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7292
    Cell Significance Index: -45.9600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.7485
    Cell Significance Index: -48.2900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.7750
    Cell Significance Index: -12.9700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.8150
    Cell Significance Index: -54.8000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9212
    Cell Significance Index: -56.4800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.9376
    Cell Significance Index: -32.5800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.9703
    Cell Significance Index: -49.0400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.0717
    Cell Significance Index: -56.2700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -1.1760
    Cell Significance Index: -19.8100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.2568
    Cell Significance Index: -21.7300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.3148
    Cell Significance Index: -37.6900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.3506
    Cell Significance Index: -36.1900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.3679
    Cell Significance Index: -40.2900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -1.4275
    Cell Significance Index: -21.0700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.4612
    Cell Significance Index: -53.6400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.5906
    Cell Significance Index: -52.0800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.6678
    Cell Significance Index: -17.2700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -1.6754
    Cell Significance Index: -34.7600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.6811
    Cell Significance Index: -28.8100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.7103
    Cell Significance Index: -25.2500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CTNND1 is a member of the catenin family, which consists of four distinct proteins: β-catenin, γ-catenin, α-catenin, and catenin delta 1 (CTNND1). The main characteristic of CTNND1 is its ability to interact with various proteins, including cadherins, β-catenin, and other catenins, to form adherens junctions. This interaction is crucial for maintaining cell-cell adhesion and regulating the activity of downstream signaling pathways. CTNND1 also exhibits protein-binding and protein-sequestering activities, which enable it to regulate the expression and function of other proteins. **Pathways and Functions** CTNND1 is involved in various signaling pathways, including: 1. **Adherens junction signaling**: CTNND1 interacts with cadherins and β-catenin to regulate cell-cell adhesion and signaling. 2. **Wnt signaling pathway**: CTNND1 negatively regulates the canonical Wnt signaling pathway by interacting with β-catenin and inhibiting its activity. 3. **Cell-cell communication**: CTNND1 regulates the expression and function of type II classical cadherins, which are essential for cell-cell communication. 4. **Infectious disease**: CTNND1 has been implicated in the regulation of Listeria monocytogenes entry into host cells, highlighting its importance in the immune response. 5. **Neurological disorders**: CTNND1 has been linked to various neurological disorders, including autism and schizophrenia, suggesting its role in synaptic plasticity and neuronal function. **Clinical Significance** CTNND1 has been implicated in various diseases, including: 1. **Infectious diseases**: CTNND1 plays a crucial role in regulating the entry of Listeria monocytogenes into host cells, highlighting its importance in the immune response. 2. **Cancers**: CTNND1 has been implicated in the regulation of cell-cell adhesion and signaling in various cancers, including breast and colon cancer. 3. **Neurological disorders**: CTNND1 is involved in synaptic plasticity and neuronal function, making it a potential target for the treatment of neurological disorders, such as autism and schizophrenia. 4. **Cardiovascular diseases**: CTNND1 has been linked to the regulation of vascular permeability and blood pressure, highlighting its potential role in cardiovascular diseases. In conclusion, CTNND1 is a multifunctional protein that plays a critical role in maintaining cell-cell adhesion, regulating signaling pathways, and regulating gene expression. Its involvement in various diseases highlights its importance in maintaining tissue homeostasis and regulating cellular processes. Further research is needed to fully understand the functions of CTNND1 and its role in disease.

Genular Protein ID: 203065753

Symbol: CTND1_HUMAN

Name: Catenin delta-1

UniProtKB Accession Codes:

O60716 A8K939 O15088 O60713 O60714 O60715 O60935 Q6DHZ7 Q6RBX8 Q9UP71 Q9UP72 Q9UP73

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 15 CORUM 1 CTD 1 CarbonylDB 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 33 Ensembl 30 EvolutionaryTrace 1 ExpressionAtlas 1 GO 30 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 32 Pumba 1 RNAct 1 Reactome 6 RefSeq 22 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9653641

Title: Molecular cloning of the human p120ctn catenin gene (CTNND1): expression of multiple alternatively spliced isoforms.

PubMed ID: 9653641

DOI: 10.1006/geno.1998.5325

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7623846

Title: The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors.

PubMed ID: 7623846

DOI: 10.1128/mcb.15.8.4553

PubMed ID: 10207085

Title: The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor.

PubMed ID: 10207085

DOI: 10.1128/mcb.19.5.3614

PubMed ID: 11896187

Title: Specific sequences in p120ctn determine subcellular distribution of its multiple isoforms involved in cellular adhesion of normal and malignant epithelial cells.

PubMed ID: 11896187

DOI: 10.1242/jcs.115.7.1391

PubMed ID: 12370829

Title: The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn).

PubMed ID: 12370829

DOI: 10.1038/sj.onc.1205858

PubMed ID: 14610055

Title: A core function for p120-catenin in cadherin turnover.

PubMed ID: 14610055

DOI: 10.1083/jcb.200307111

PubMed ID: 14699141

Title: Laminar shear stress differentially modulates gene expression of p120 catenin, Kaiso transcription factor, and vascular endothelial cadherin in human coronary artery endothelial cells.

PubMed ID: 14699141

DOI: 10.1074/jbc.m306057200

PubMed ID: 15240885

Title: A role for Galpha12/Galpha13 in p120ctn regulation.

PubMed ID: 15240885

DOI: 10.1073/pnas.0401366101

PubMed ID: 17047063

Title: E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion.

PubMed ID: 17047063

DOI: 10.1158/0008-5472.can-05-3096

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17115030

Title: The armadillo protein p0071 regulates Rho signalling during cytokinesis.

PubMed ID: 17115030

DOI: 10.1038/ncb1504

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 17344476

Title: The transcriptional repressor Glis2 is a novel binding partner for p120 catenin.

PubMed ID: 17344476

DOI: 10.1091/mbc.e06-10-0941

PubMed ID: 17194753

Title: Specific phosphorylation of p120-catenin regulatory domain differently modulates its binding to RhoA.

PubMed ID: 17194753

DOI: 10.1128/mcb.01974-06

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20564219

Title: p120-catenin is a binding partner and substrate for Group B Pak kinases.

PubMed ID: 20564219

DOI: 10.1002/jcb.22639

PubMed ID: 20123964

Title: Lipid phosphate phosphatase 3 stabilization of beta-catenin induces endothelial cell migration and formation of branching point structures.

PubMed ID: 20123964

DOI: 10.1128/mcb.00038-09

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25009281

Title: DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia.

PubMed ID: 25009281

DOI: 10.1091/mbc.e13-08-0492

PubMed ID: 28301459

Title: Blepharocheilodontic syndrome is a CDH1 pathway-related disorder due to mutations in CDH1 and CTNND1.

PubMed ID: 28301459

DOI: 10.1038/gim.2017.11

PubMed ID: 28051089

Title: Cadherin 26 is an alpha integrin-binding epithelial receptor regulated during allergic inflammation.

PubMed ID: 28051089

DOI: 10.1038/mi.2016.120

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 20371349

Title: Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.

PubMed ID: 20371349

DOI: 10.1016/j.cell.2010.01.017

Sequence Information:

  • Length: 968
  • Mass: 108170
  • Checksum: D5C37489A891F292
  • Sequence:
    • MDDSEVESTA SILASVKEQE AQFEKLTRAL EEERRHVSAQ LERVRVSPQD ANPLMANGTL 
TRRHQNGRFV GDADLERQKF SDLKLNGPQD HSHLLYSTIP RMQEPGQIVE TYTEEDPEGA 
MSVVSVETSD DGTTRRTETT VKKVVKTVTT RTVQPVAMGP DGLPVDASSV SNNYIQTLGR 
DFRKNGNGGP GPYVGQAGTA TLPRNFHYPP DGYSRHYEDG YPGGSDNYGS LSRVTRIEER 
YRPSMEGYRA PSRQDVYGPQ PQVRVGGSSV DLHRFHPEPY GLEDDQRSMG YDDLDYGMMS 
DYGTARRTGT PSDPRRRLRS YEDMIGEEVP SDQYYWAPLA QHERGSLASL DSLRKGGPPP 
PNWRQPELPE VIAMLGFRLD AVKSNAAAYL QHLCYRNDKV KTDVRKLKGI PVLVGLLDHP 
KKEVHLGACG ALKNISFGRD QDNKIAIKNC DGVPALVRLL RKARDMDLTE VITGTLWNLS 
SHDSIKMEIV DHALHALTDE VIIPHSGWER EPNEDCKPRH IEWESVLTNT AGCLRNVSSE 
RSEARRKLRE CDGLVDALIF IVQAEIGQKD SDSKLVENCV CLLRNLSYQV HREIPQAERY 
QEAAPNVANN TGPHAASCFG AKKGKDEWFS RGKKPIEDPA NDTVDFPKRT SPARGYELLF 
QPEVVRIYIS LLKESKTPAI LEASAGAIQN LCAGRWTYGR YIRSALRQEK ALSAIADLLT 
NEHERVVKAA SGALRNLAVD ARNKELIGKH AIPNLVKNLP GGQQNSSWNF SEDTVISILN 
TINEVIAENL EAAKKLRETQ GIEKLVLINK SGNRSEKEVR AAALVLQTIW GYKELRKPLE 
KEGWKKSDFQ VNLNNASRSQ SSHSYDDSTL PLIDRNQKSD KKPDREEIQM SNMGSNTKSL 
DNNYSTPNER GDHNRTLDRS GDLGDMEPLK GTTPLMQDEG QESLEEELDV LVLDDEGGQV 
SYPSMQKI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.