Details for: CTPS1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.78
Marker Score: 3900 - Cell Name: male germ cell (CL0000015)
Fold Change: 1.26
Marker Score: 363 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.22
Marker Score: 1529.5 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.1
Marker Score: 1581 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.06
Marker Score: 2489 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.05
Marker Score: 16495 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.03
Marker Score: 2814 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1
Marker Score: 6444 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71749 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47973 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30401 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.98
Marker Score: 662 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.97
Marker Score: 306 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.96
Marker Score: 879 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2405 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 485 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.93
Marker Score: 34480 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 441 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2716 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.9
Marker Score: 2048 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.88
Marker Score: 946 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.87
Marker Score: 656 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5293 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 311 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.86
Marker Score: 4894 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.85
Marker Score: 855 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.84
Marker Score: 1702.5 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.83
Marker Score: 500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.82
Marker Score: 7071 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.81
Marker Score: 847 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.81
Marker Score: 853 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.8
Marker Score: 11997 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.8
Marker Score: 4810 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1262 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.78
Marker Score: 3352 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.76
Marker Score: 305 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.76
Marker Score: 1172 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.76
Marker Score: 3133 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.75
Marker Score: 1001 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.75
Marker Score: 191 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.75
Marker Score: 571.5 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.74
Marker Score: 353 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.74
Marker Score: 694 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.73
Marker Score: 784.5 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 379 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.73
Marker Score: 234 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.72
Marker Score: 270 - Cell Name: brush cell (CL0002204)
Fold Change: 0.71
Marker Score: 645 - Cell Name: Unknown (CL0000548)
Fold Change: 0.7
Marker Score: 513 - Cell Name: neuron (CL0000540)
Fold Change: 0.7
Marker Score: 2853 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.69
Marker Score: 346 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.69
Marker Score: 3731 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.69
Marker Score: 2822 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.69
Marker Score: 7097 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.68
Marker Score: 6879 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 0.68
Marker Score: 935 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 173 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.67
Marker Score: 2817.5 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.64
Marker Score: 6081 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.63
Marker Score: 433 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.62
Marker Score: 1055 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.62
Marker Score: 684 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.62
Marker Score: 659 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.62
Marker Score: 2577 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.61
Marker Score: 387 - Cell Name: neural cell (CL0002319)
Fold Change: 0.6
Marker Score: 290 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.6
Marker Score: 1153 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.6
Marker Score: 22649 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.59
Marker Score: 666 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.58
Marker Score: 251 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.58
Marker Score: 153 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.57
Marker Score: 195 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.57
Marker Score: 606 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.57
Marker Score: 1335.5 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.56
Marker Score: 174 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.55
Marker Score: 11021 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 0.55
Marker Score: 2720 - Cell Name: Unknown (CL0002371)
Fold Change: 0.55
Marker Score: 587 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.55
Marker Score: 372 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.54
Marker Score: 287 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 432 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.54
Marker Score: 1128 - Cell Name: epithelial cell (CL0000066)
Fold Change: 0.54
Marker Score: 859 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.54
Marker Score: 140 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.54
Marker Score: 354 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.53
Marker Score: 32780 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.53
Marker Score: 257 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.53
Marker Score: 2045 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.52
Marker Score: 183 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 0.52
Marker Score: 181 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.52
Marker Score: 327 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.52
Marker Score: 195 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.51
Marker Score: 578 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 0.51
Marker Score: 323 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.51
Marker Score: 3923 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 0.51
Marker Score: 1425 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.5
Marker Score: 483 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.5
Marker Score: 1485 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 0.49
Marker Score: 324 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.49
Marker Score: 123
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Other Information
Genular Protein ID: 3185243367
Symbol: PYRG1_HUMAN
Name: CTP synthetase 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2113467
Title: Molecular cloning of the human CTP synthetase gene by functional complementation with purified human metaphase chromosomes.
PubMed ID: 2113467
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16179339
Title: Expression of human CTP synthetase in Saccharomyces cerevisiae reveals phosphorylation by protein kinase A.
PubMed ID: 16179339
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17487921
Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.
PubMed ID: 17487921
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18088087
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24870241
Title: CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation.
PubMed ID: 24870241
DOI: 10.1038/nature13386
PubMed ID: 25223282
Title: Ack kinase regulates CTP synthase filaments during Drosophila oogenesis.
PubMed ID: 25223282
PubMed ID: 16820675
Title: Structure of the synthetase domain of human CTP synthetase, a target for anticancer therapy.
PubMed ID: 16820675
Sequence Information:
- Length: 591
- Mass: 66690
- Checksum: 0B04F9D9390C4152
- Sequence:
MKYILVTGGV ISGIGKGIIA SSVGTILKSC GLHVTSIKID PYINIDAGTF SPYEHGEVFV LDDGGEVDLD LGNYERFLDI RLTKDNNLTT GKIYQYVINK ERKGDYLGKT VQVVPHITDA IQEWVMRQAL IPVDEDGLEP QVCVIELGGT VGDIESMPFI EAFRQFQFKV KRENFCNIHV SLVPQPSSTG EQKTKPTQNS VRELRGLGLS PDLVVCRCSN PLDTSVKEKI SMFCHVEPEQ VICVHDVSSI YRVPLLLEEQ GVVDYFLRRL DLPIERQPRK MLMKWKEMAD RYDRLLETCS IALVGKYTKF SDSYASVIKA LEHSALAINH KLEIKYIDSA DLEPITSQEE PVRYHEAWQK LCSAHGVLVP GGFGVRGTEG KIQAIAWARN QKKPFLGVCL GMQLAVVEFS RNVLGWQDAN STEFDPTTSH PVVVDMPEHN PGQMGGTMRL GKRRTLFQTK NSVMRKLYGD ADYLEERHRH RFEVNPVWKK CLEEQGLKFV GQDVEGERME IVELEDHPFF VGVQYHPEFL SRPIKPSPPY FGLLLASVGR LSHYLQKGCR LSPRDTYSDR SGSSSPDSEI TELKFPSINH D
Genular Protein ID: 1098899016
Symbol: B4E1E0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 17487921
Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.
PubMed ID: 17487921
PubMed ID: 18088087
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
Sequence Information:
- Length: 435
- Mass: 49695
- Checksum: 6FF471FBC7746644
- Sequence:
MPFIEAFRQF QFKVKRENFC NIHVSLVPQP SSTGEQKTKP TQNSVRELRG LGLSPDLVVC RCSNPLDTSV KEKISMFCHV EPEQVICVHD VSSIYRVPLL LEEQGVVDYF LRRLDLPIER QPRKMLMKWK EMADRYDRLL ETCSIALVGK YTKFSDSYAS VIKALEHSAL AINHKLEIKY IDSADLEPIT SQEEPVRYHE AWQKLCSAHG VLVPGGFGVR GTEGKIQAIA WARNQKKPFL GVCLGMQLAV VEFSRNVLGW QDANSTEFDP TTSHPVVVDM PEHNPGQMGG TMRLGKRRTL FQTKNSVMRK LYGDADYLEE RHRHRFEVNP VWKKCLEEQG LKFVGQDVEG ERMEIVELED HPFFVGVQYH PEFLSRPIKP SPPYFGLLLA SVGRLSHYLQ KGCRLSPRDT YSDRSGSSSP DSEITELKFP SINHD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.