Details for: H2 T3

Gene ID: 15043

Symbol: H2 T3

Ensembl ID: ENSMUSG00000054128

Description: histocompatibility 2, T region locus 3

Associated with

  • Adaptive immune response
    (GO:0002250)
  • Antibacterial humoral response
    (GO:0019731)
  • Antigen processing and presentation of endogenous peptide antigen via mhc class ib
    (GO:0002476)
  • Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway, tap-independent
    (GO:0002486)
  • Antigen processing and presentation of exogenous peptide antigen via mhc class ib
    (GO:0002477)
  • Beta-2-microglobulin binding
    (GO:0030881)
  • Cd8-positive, alpha-beta t cell activation
    (GO:0036037)
  • Cell surface
    (GO:0009986)
  • Defense response to gram-positive bacterium
    (GO:0050830)
  • Endoplasmic reticulum
    (GO:0005783)
  • External side of plasma membrane
    (GO:0009897)
  • Extracellular space
    (GO:0005615)
  • Golgi apparatus
    (GO:0005794)
  • Immune response
    (GO:0006955)
  • Lumenal side of endoplasmic reticulum membrane
    (GO:0098553)
  • Mhc class ib protein complex
    (GO:0032398)
  • Mhc class i protein binding
    (GO:0042288)
  • Mhc class i protein complex
    (GO:0042612)
  • Natural killer cell lectin-like receptor binding
    (GO:0046703)
  • Natural killer cell tolerance induction
    (GO:0002519)
  • Negative regulation of natural killer cell activation
    (GO:0032815)
  • Negative regulation of natural killer cell mediated cytotoxicity
    (GO:0045953)
  • Negative regulation of t cell proliferation
    (GO:0042130)
  • Peptide antigen binding
    (GO:0042605)
  • Phagocytic vesicle membrane
    (GO:0030670)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of antibody-dependent cellular cytotoxicity
    (GO:0001815)
  • Positive regulation of cd8-positive, alpha-beta t cell activation
    (GO:2001187)
  • Positive regulation of cd8-positive, alpha-beta t cell proliferation
    (GO:2000566)
  • Positive regulation of immunoglobulin production
    (GO:0002639)
  • Positive regulation of interleukin-4 production
    (GO:0032753)
  • Positive regulation of interleukin-13 production
    (GO:0032736)
  • Positive regulation of natural killer cell activation
    (GO:0032816)
  • Positive regulation of natural killer cell cytokine production
    (GO:0002729)
  • Positive regulation of natural killer cell mediated cytotoxicity
    (GO:0045954)
  • Positive regulation of natural killer cell mediated immunity
    (GO:0002717)
  • Positive regulation of natural killer cell proliferation
    (GO:0032819)
  • Positive regulation of t cell mediated cytotoxicity
    (GO:0001916)
  • Positive regulation of trail production
    (GO:0032759)
  • Positive regulation of tumor necrosis factor production
    (GO:0032760)
  • Protection from natural killer cell mediated cytotoxicity
    (GO:0042270)
  • Protein-folding chaperone binding
    (GO:0051087)
  • Regulation of natural killer cell mediated immunity
    (GO:0002715)
  • Signaling receptor binding
    (GO:0005102)
  • T cell receptor binding
    (GO:0042608)

Other Information

Genular Protein ID: 1202784034

Symbol: Q05A75_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q05A75

Database IDs:

AGR 1 ARBA 9 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 4 Ensembl 4 ExpressionAtlas 1 GO 1 Gene3D 2 GeneTree 1 HOGENOM 1 InterPro 9 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 3 SMART 1 SMR 1 SUPFAM 2 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 384
  • Mass: 43544
  • Checksum: CC32654364B26218
  • Sequence:
    • MRMGTMVPGT LLILLAASQG QTQTCPGSHS LRYFYTALSR PAISEPWYIA VGYLDDTQFV 
RFNSSGETAT YKLSAPWVEQ EGPEYWARET EIVTSNAQFF RENLQTMLDY YNLSQNGSHT 
IQVMYGCEVE FFGSLFRAYE QHGYDGRDYI ALNEDLKTWT AADTAAEITR SKWEQAGYTE 
LRRTYLEGPC KDSLLRYLEN RKKTQECTDP PKTHVTHHPR PEGYVTLRCW ALRFYPADIT 
LTWQLNGEEL IQDTELVETR PAGDGTFQKW AAVVVPLGKE QKYTCHVYHE GLPEPLTLRW 
EPPQTSMPNR TTVRALLGAM IILGFMSGSV MMWMRKNNGG NGDDNTAAYQ NEREHLSLSP 
RAESEALGVE AGMKDLPSAP PLVS

Genular Protein ID: 2126409380

Symbol: Q8HWB4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8HWB4

Database IDs:

AGR 1 ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 1 Gene3D 2 Genevisible 1 InterPro 9 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 Pfam 2 RefSeq 1 RuleBase 1 SAM 3 SMART 1 SUPFAM 2

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 384
  • Mass: 43553
  • Checksum: 5287884DB75F521C
  • Sequence:
    • MRMGTMVPGT LLILLAASQG QTQTCPGSHS LRYFYTALSR PAISEPWYIA VGYLDDTQFV 
RFNSSGETAT YKLSAPWVEQ EGPEYWARET EIVTSNAQFF RENLHTMLDY YNLSQNGSHT 
IQVMYGCEVE FFGSLFRAYE QHGYDGRDYI ALNEDLKTWT AADTAAEITR SKWEQAGYTE 
LRRTYLEGPC KDSLLRYLEN RKKTQECTDP PKTHVTHHPR PEGYVTLRCW ALRFYPADIT 
LTWQLNGEEL IQDTELVETR PAGDGTFQKW AAVVVPLGKE QKYTCHVYHE GLPEPLTLRW 
EPPQTSMPNR TTVRALLGAM IILGFMSGSV MMWMRKNNGG NGDDNTAAYQ NEREHLSLSP 
RAESEALGVE AGMKDLPSAP PLVS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.