Has3 | ENSMUSG00000031910 | NCBI 15118

Details for: Has3

Gene ID: 15118

Symbol: Has3

Ensembl ID: ENSMUSG00000031910

Description: hyaluronan synthase 3

Associated with

Glycosaminoglycan metabolism
(R-MMU-1630316)
Hyaluronan biosynthesis and export
(R-MMU-2142850)
Hyaluronan metabolism
(R-MMU-2142845)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Extracellular matrix assembly
(GO:0085029)
Extracellular polysaccharide biosynthetic process
(GO:0045226)
Glycosyltransferase activity
(GO:0016757)
Golgi apparatus
(GO:0005794)
Hyaluranon cable
(GO:0036117)
Hyaluronan biosynthetic process
(GO:0030213)
Hyaluronan synthase activity
(GO:0050501)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of hyaluranon cable assembly
(GO:1900106)
Transferase activity
(GO:0016740)

Other Information

Proteins

Hyaluronan synthase 3

Genular Protein ID: 2991246321

Symbol: HYAS3_MOUSE

Name: Hyaluronan synthase 3

UniProtKB Accession Codes:

O08650 Q8CEB9

Database IDs:

Citations:

PubMed ID: 9083017

Title: Molecular cloning and characterization of a cDNA encoding the third putative mammalian hyaluronan synthase.

PubMed ID: 9083017

DOI: 10.1074/jbc.272.14.8957

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10455188

Title: Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties.

PubMed ID: 10455188

DOI: 10.1074/jbc.274.35.25085

PubMed ID: 16014622

Title: Plasma membrane residence of hyaluronan synthase is coupled to its enzymatic activity.

PubMed ID: 16014622

DOI: 10.1074/jbc.m504736200

PubMed ID: 24790187

Title: Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space.

PubMed ID: 24790187

DOI: 10.1523/jneurosci.3458-13.2014

Sequence Information:

Length: 554
Mass: 63349
Checksum: BFFF239C901251DE
Sequence:

MPVQLTTALR VVGTSLFALV VLGGILAAYV TGYQFIHTEK HYLSFGLYGA ILGLHLLIQS 
LFAFLEHRRM RRAGRPLKLH CSQRPRSVAL CIAAYQEDPE YLRKCLRSAQ RIAFPNLKVV 
MVVDGNRQED TYMLDIFHEV LGGTEQAGFF VWRSNFHEAG EGETEASLQE GMERVRAVVW 
ASTFSCIMQK WGGKREVMYT AFKALGNSVD YIQVCDSDTV LDPACTIEML RVLEEDPQVG 
GVGGDVQILN KYDSWISFLS SVRYWMAFNV ERACQSYFGC VQCISGPLGM YRNSLLQQFL 
EDWYHQKFLG SKCSFGDDRH LTNRVLSLGY RTKYTARSKC LTETPTRYLR WLNQQTRWSK 
SYFREWLYNS LWFHKHHLWM TYESVVTGFF PFFLIATVIQ LFYRGRIWNI LLFLLTVQLV 
GIIKATYACF LRGNAEMIFM SLYSLLYMSS LLPAKIFAIA TINKSGWGTS GRKTIVVNFI 
GLIPVSIWVA VLLGGLAYTA YCQDLFSETE LAFLVSGAIL YGCYWVALLM LYLAIIARRC 
GKKPEQYSLA FAEV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Has3

Associated with

Other Information

Molecular cloning and characterization of a cDNA encoding the third putative mammalian hyaluronan synthase. PubMed ID: 9083017

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. PubMed ID: 10455188

Plasma membrane residence of hyaluronan synthase is coupled to its enzymatic activity. PubMed ID: 16014622