Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 198.6560
Cell Significance Index: -30.9000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 123.8353
Cell Significance Index: -31.4100 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 91.5165
Cell Significance Index: -37.7000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 83.9616
Cell Significance Index: -34.1100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 68.7533
Cell Significance Index: -32.4600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 68.2562
Cell Significance Index: -35.1100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 35.9573
Cell Significance Index: -34.3300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 25.0131
Cell Significance Index: -30.8400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 12.7256
Cell Significance Index: -34.0900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 7.9675
Cell Significance Index: -31.4400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 7.3061
Cell Significance Index: -15.9900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 4.8387
Cell Significance Index: 54.9700 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 4.6276
Cell Significance Index: 85.5300 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 4.1452
Cell Significance Index: 121.7400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 4.0863
Cell Significance Index: 212.2700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 3.7677
Cell Significance Index: 463.2800 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 3.6378
Cell Significance Index: 64.2900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 3.5412
Cell Significance Index: 638.3800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 3.4066
Cell Significance Index: 648.3000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.0816
Cell Significance Index: 83.8800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.8723
Cell Significance Index: 338.7300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.1780
Cell Significance Index: 101.5500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 2.1165
Cell Significance Index: 19.4900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.9974
Cell Significance Index: 119.9100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.8571
Cell Significance Index: 255.0300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.5810
Cell Significance Index: 257.1400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 1.4573
Cell Significance Index: 1103.0800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.9961
Cell Significance Index: 543.9900 - Cell Name: centroblast (CL0009112)
Fold Change: 0.8144
Cell Significance Index: 1.9000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.7545
Cell Significance Index: 39.3000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.6854
Cell Significance Index: 14.8500 - Cell Name: peg cell (CL4033014)
Fold Change: 0.6700
Cell Significance Index: 15.4800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6615
Cell Significance Index: 597.3300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.6015
Cell Significance Index: 44.8300 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.5100
Cell Significance Index: 65.8900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4281
Cell Significance Index: 29.6100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4278
Cell Significance Index: 42.3200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.3996
Cell Significance Index: 79.3100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.2778
Cell Significance Index: 17.9300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2735
Cell Significance Index: 7.8800 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1644
Cell Significance Index: 21.0700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1145
Cell Significance Index: 19.5600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0956
Cell Significance Index: 2.3900 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.0562
Cell Significance Index: 5.7400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0501
Cell Significance Index: 36.7500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0428
Cell Significance Index: 80.5500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0312
Cell Significance Index: 6.2600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0014
Cell Significance Index: -0.6300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0032
Cell Significance Index: -1.1700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0047
Cell Significance Index: -0.2200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0072
Cell Significance Index: -13.3600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0102
Cell Significance Index: -15.7400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0142
Cell Significance Index: -19.3300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0144
Cell Significance Index: -10.6600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0148
Cell Significance Index: -0.5200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0198
Cell Significance Index: -1.0000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0217
Cell Significance Index: -13.5200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0412
Cell Significance Index: -26.1700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0426
Cell Significance Index: -24.0300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0549
Cell Significance Index: -6.2900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0595
Cell Significance Index: -1.5900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0609
Cell Significance Index: -1.6300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0678
Cell Significance Index: -30.7700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0840
Cell Significance Index: -24.1600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1015
Cell Significance Index: -4.6000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1083
Cell Significance Index: -3.4700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1144
Cell Significance Index: -24.0900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1429
Cell Significance Index: -1.9500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1507
Cell Significance Index: -17.5600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1518
Cell Significance Index: -22.0600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1859
Cell Significance Index: -21.2300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.2221
Cell Significance Index: -4.7300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2852
Cell Significance Index: -29.7000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2970
Cell Significance Index: -22.8000 - Cell Name: pulmonary alveolar type 2 cell (CL0002063)
Fold Change: -0.3131
Cell Significance Index: -2.5900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.3188
Cell Significance Index: -3.3000 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.3271
Cell Significance Index: -5.0600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3362
Cell Significance Index: -26.6300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3710
Cell Significance Index: -24.9500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3979
Cell Significance Index: -28.1400 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.4008
Cell Significance Index: -16.4200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.4085
Cell Significance Index: -11.7100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4101
Cell Significance Index: -25.1500 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: -0.4435
Cell Significance Index: -3.3900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4538
Cell Significance Index: -28.6000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.4555
Cell Significance Index: -12.7300 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.5568
Cell Significance Index: -16.4000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.5730
Cell Significance Index: -35.2200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.5776
Cell Significance Index: -32.4100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.6078
Cell Significance Index: -31.9100 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.6572
Cell Significance Index: -4.2900 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.6682
Cell Significance Index: -17.5700 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -0.7144
Cell Significance Index: -14.9000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.7501
Cell Significance Index: -33.1800 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: -0.7549
Cell Significance Index: -6.1200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.7619
Cell Significance Index: -26.6900 - Cell Name: monocyte-derived dendritic cell (CL0011031)
Fold Change: -0.7683
Cell Significance Index: -13.2000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.7886
Cell Significance Index: -21.1300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.7977
Cell Significance Index: -27.7200 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.8208
Cell Significance Index: -30.1300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1771692746
Symbol: CATH_HUMAN
Name: Pro-cathepsin H
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2587265
Title: Nucleotide sequence of human preprocathepsin H, a lysosomal cysteine proteinase.
PubMed ID: 2587265
PubMed ID: 11796715
Title: Analysis of a truncated form of cathepsin H in human prostate tumor cells.
PubMed ID: 11796715
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2849458
Title: Molecular cloning and sequencing of a cDNA coding for mature human kidney cathepsin H.
PubMed ID: 2849458
PubMed ID: 3342889
Title: Amino acid sequences of the human kidney cathepsins H and L.
PubMed ID: 3342889
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 335
- Mass: 37394
- Checksum: E2CF3A5EEA59C1D1
- Sequence:
MWATLPLLCA GAWLLGVPVC GAAELCVNSL EKFHFKSWMS KHRKTYSTEE YHHRLQTFAS NWRKINAHNN GNHTFKMALN QFSDMSFAEI KHKYLWSEPQ NCSATKSNYL RGTGPYPPSV DWRKKGNFVS PVKNQGACGS CWTFSTTGAL ESAIAIATGK MLSLAEQQLV DCAQDFNNHG CQGGLPSQAF EYILYNKGIM GEDTYPYQGK DGYCKFQPGK AIGFVKDVAN ITIYDEEAMV EAVALYNPVS FAFEVTQDFM MYRTGIYSST SCHKTPDKVN HAVLAVGYGE KNGIPYWIVK NSWGPQWGMN GYFLIERGKN MCGLAACASY PIPLV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.