CTSH | ENSG00000103811 | NCBI 1512

Details for: CTSH

Gene ID: 1512

Symbol: CTSH

Ensembl ID: ENSG00000103811

Description: cathepsin H

Associated with

Adaptive immune system
(R-HSA-1280218)
Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Metabolism of proteins
(R-HSA-392499)
Mhc class ii antigen presentation
(R-HSA-2132295)
Neutrophil degranulation
(R-HSA-6798695)
Surfactant metabolism
(R-HSA-5683826)
Adaptive immune response
(GO:0002250)
Alveolar lamellar body
(GO:0097208)
Aminopeptidase activity
(GO:0004177)
Antigen processing and presentation
(GO:0019882)
Apoptotic process
(GO:0006915)
Bradykinin catabolic process
(GO:0010815)
Cellular response to thyroid hormone stimulus
(GO:0097067)
Collagen-containing extracellular matrix
(GO:0062023)
Cysteine-type endopeptidase activator activity involved in apoptotic process
(GO:0008656)
Cysteine-type endopeptidase activity
(GO:0004197)
Cysteine-type peptidase activity
(GO:0008234)
Cytoplasmic ribonucleoprotein granule
(GO:0036464)
Cytosol
(GO:0005829)
Dichotomous subdivision of terminal units involved in lung branching
(GO:0060448)
Endopeptidase activity
(GO:0004175)
Erk1 and erk2 cascade
(GO:0070371)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Ficolin-1-rich granule lumen
(GO:1904813)
Hla-a specific activating mhc class i receptor activity
(GO:0030108)
Immune response
(GO:0006955)
Immune response-regulating signaling pathway
(GO:0002764)
Intracellular membrane-bounded organelle
(GO:0043231)
Lysosome
(GO:0005764)
Membrane protein proteolysis
(GO:0033619)
Metanephros development
(GO:0001656)
Multivesicular body lumen
(GO:0097486)
Negative regulation of apoptotic process
(GO:0043066)
Neuropeptide catabolic process
(GO:0010813)
Peptidase activity
(GO:0008233)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of apoptotic signaling pathway
(GO:2001235)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of epithelial cell migration
(GO:0010634)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of peptidase activity
(GO:0010952)
Protein binding
(GO:0005515)
Protein destabilization
(GO:0031648)
Proteolysis
(GO:0006508)
Proteolysis involved in protein catabolic process
(GO:0051603)
Response to retinoic acid
(GO:0032526)
Secretory granule lumen
(GO:0034774)
Serine-type endopeptidase activity
(GO:0004252)
Surfactant homeostasis
(GO:0043129)
T cell mediated cytotoxicity
(GO:0001913)
Tertiary granule lumen
(GO:1904724)
Thyroid hormone binding
(GO:0070324)
Zymogen activation
(GO:0031638)

Other Information

Proteins

Pro-cathepsin H

Genular Protein ID: 1771692746

Symbol: CATH_HUMAN

Name: Pro-cathepsin H

UniProtKB Accession Codes:

P09668 B2RBK0 Q96NY6 Q9BUM7

Database IDs:

Citations:

PubMed ID: 2587265

Title: Nucleotide sequence of human preprocathepsin H, a lysosomal cysteine proteinase.

PubMed ID: 2587265

DOI: 10.1093/nar/17.22.9471

PubMed ID: 11796715

Title: Analysis of a truncated form of cathepsin H in human prostate tumor cells.

PubMed ID: 11796715

DOI: 10.1074/jbc.m109557200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2849458

Title: Molecular cloning and sequencing of a cDNA coding for mature human kidney cathepsin H.

PubMed ID: 2849458

DOI: 10.1515/bchm3.1988.369.1.469

PubMed ID: 3342889

Title: Amino acid sequences of the human kidney cathepsins H and L.

PubMed ID: 3342889

DOI: 10.1016/0014-5793(88)80028-0

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 335
Mass: 37394
Checksum: E2CF3A5EEA59C1D1
Sequence:

MWATLPLLCA GAWLLGVPVC GAAELCVNSL EKFHFKSWMS KHRKTYSTEE YHHRLQTFAS 
NWRKINAHNN GNHTFKMALN QFSDMSFAEI KHKYLWSEPQ NCSATKSNYL RGTGPYPPSV 
DWRKKGNFVS PVKNQGACGS CWTFSTTGAL ESAIAIATGK MLSLAEQQLV DCAQDFNNHG 
CQGGLPSQAF EYILYNKGIM GEDTYPYQGK DGYCKFQPGK AIGFVKDVAN ITIYDEEAMV 
EAVALYNPVS FAFEVTQDFM MYRTGIYSST SCHKTPDKVN HAVLAVGYGE KNGIPYWIVK 
NSWGPQWGMN GYFLIERGKN MCGLAACASY PIPLV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CTSH

Associated with

Other Information

Nucleotide sequence of human preprocathepsin H, a lysosomal cysteine proteinase. PubMed ID: 2587265

Analysis of a truncated form of cathepsin H in human prostate tumor cells. PubMed ID: 11796715

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Analysis of the DNA sequence and duplication history of human chromosome 15. PubMed ID: 16572171

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Molecular cloning and sequencing of a cDNA coding for mature human kidney cathepsin H. PubMed ID: 2849458

Amino acid sequences of the human kidney cathepsins H and L. PubMed ID: 3342889

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

Initial characterization of the human central proteome. PubMed ID: 21269460

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974