Details for: Hcn1
Associated with
Other Information
Genular Protein ID: 2869902897
Symbol: HCN1_MOUSE
Name: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9405696
Title: Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.
PubMed ID: 9405696
PubMed ID: 9634236
Title: A family of hyperpolarization-activated cation channels.
PubMed ID: 9634236
DOI: 10.1038/31255
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 9630217
Title: Identification of a gene encoding a hyperpolarization-activated 'pacemaker' channel of brain.
PubMed ID: 9630217
PubMed ID: 11420311
Title: MinK-related peptide 1: a beta subunit for the HCN ion channel subunit family enhances expression and speeds activation.
PubMed ID: 11420311
PubMed ID: 11459060
Title: Molecular mechanism of cAMP modulation of HCN pacemaker channels.
PubMed ID: 11459060
DOI: 10.1038/35081088
PubMed ID: 11675786
Title: Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli.
PubMed ID: 11675786
DOI: 10.1038/35098087
PubMed ID: 12089064
Title: Dominant-negative suppression of HCN1- and HCN2-encoded pacemaker currents by an engineered HCN1 construct: insights into structure-function relationships and multimerization.
PubMed ID: 12089064
PubMed ID: 12034718
Title: Different roles for the cyclic nucleotide binding domain and amino terminus in assembly and expression of hyperpolarization-activated, cyclic nucleotide-gated channels.
PubMed ID: 12034718
PubMed ID: 12351622
Title: An external determinant in the S5-P linker of the pacemaker (HCN) channel identified by sulfhydryl modification.
PubMed ID: 12351622
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 26269648
Title: Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing.
PubMed ID: 26269648
PubMed ID: 22006928
Title: Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
PubMed ID: 22006928
Sequence Information:
- Length: 910
- Mass: 102432
- Checksum: 56FD5F328DD972E9
- Sequence:
MEGGGKPNSA SNSRDDGNSV FPSKAPATGP VAADKRLGTP PGGGAAGKEH GNSVCFKVDG GGGEEPAGSF EDAEGPRRQY GFMQRQFTSM LQPGVNKFSL RMFGSQKAVE KEQERVKTAG FWIIHPYSDF RFYWDLIMLI MMVGNLVIIP VGITFFTEQT TTPWIIFNVA SDTVFLLDLI MNFRTGTVNE DSSEIILDPK VIKMNYLKSW FVVDFISSIP VDYIFLIVEK GMDSEVYKTA RALRIVRFTK ILSLLRLLRL SRLIRYIHQW EEIFHMTYDL ASAVVRIFNL IGMMLLLCHW DGCLQFLVPL LQDFPPDCWV SLNEMVNDSW GKQYSYALFK AMSHMLCIGY GAQAPVSMSD LWITMLSMIV GATCYAMFVG HATALIQSLD SSRRQYQEKY KQVEQYMSFH KLPADMRQKI HDYYEHRYQG KIFDEENILS ELNDPLREEI VNFNCRKLVA TMPLFANADP NFVTAMLSKL RFEVFQPGDY IIREGAVGKK MYFIQHGVAG VITKSSKEMK LTDGSYFGEI CLLTKGRRTA SVRADTYCRL YSLSVDNFNE VLEEYPMMRR AFETVAIDRL DRIGKKNSIL LQKFQKDLNT GVFNNQENEI LKQIVKHDRE MVQAIPPINY PQMTALNCTS STTTPTSRMR TQSPPVYTAT SLSHSNLHSP SPSTQTPQPS AILSPCSYTT AVCSPPIQSP LATRTFHYAS PTASQLSLMQ QPQQQLPQSQ VQQTQTQTQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQPQTPG SSTPKNEVHK STQALHNTNL TKEVRPLSAS QPSLPHEVST LISRPHPTVG ESLASIPQPV AAVHSTGLQA GSRSTVPQRV TLFRQMSSGA IPPNRGVPPA PPPPAAVQRE SPSVLNTDPD AEKPRFASNL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.