Details for: Hcn2
Associated with
Other Information
Genular Protein ID: 1854975728
Symbol: HCN2_MOUSE
Name: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9634236
Title: A family of hyperpolarization-activated cation channels.
PubMed ID: 9634236
DOI: 10.1038/31255
PubMed ID: 9630217
Title: Identification of a gene encoding a hyperpolarization-activated 'pacemaker' channel of brain.
PubMed ID: 9630217
PubMed ID: 10962006
Title: Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.
PubMed ID: 10962006
PubMed ID: 11420311
Title: MinK-related peptide 1: a beta subunit for the HCN ion channel subunit family enhances expression and speeds activation.
PubMed ID: 11420311
PubMed ID: 11096117
Title: A single histidine residue determines the pH sensitivity of the pacemaker channel HCN2.
PubMed ID: 11096117
PubMed ID: 11553787
Title: The S4-S5 linker couples voltage sensing and activation of pacemaker channels.
PubMed ID: 11553787
PubMed ID: 11741901
Title: Pacemaker channels produce an instantaneous current.
PubMed ID: 11741901
PubMed ID: 12034718
Title: Different roles for the cyclic nucleotide binding domain and amino terminus in assembly and expression of hyperpolarization-activated, cyclic nucleotide-gated channels.
PubMed ID: 12034718
PubMed ID: 12193608
Title: A conserved domain in the NH2 terminus important for assembly and functional expression of pacemaker channels.
PubMed ID: 12193608
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 21347269
Title: The cGMP-dependent protein kinase II Is an inhibitory modulator of the hyperpolarization-activated HCN2 channel.
PubMed ID: 21347269
PubMed ID: 23103389
Title: Local and global interpretations of a disease-causing mutation near the ligand entry path in hyperpolarization-activated cAMP-gated channel.
PubMed ID: 23103389
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 12968185
Title: Structural basis for modulation and agonist specificity of HCN pacemaker channels.
PubMed ID: 12968185
DOI: 10.1038/nature01922
PubMed ID: 17562314
Title: Structure and rearrangements in the carboxy-terminal region of SpIH channels.
PubMed ID: 17562314
PubMed ID: 18367452
Title: C-terminal movement during gating in cyclic nucleotide-modulated channels.
PubMed ID: 18367452
PubMed ID: 19525958
Title: Mapping the structure and conformational movements of proteins with transition metal ion FRET.
PubMed ID: 19525958
DOI: 10.1038/nmeth.1341
PubMed ID: 22550182
Title: Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels.
PubMed ID: 22550182
Sequence Information:
- Length: 863
- Mass: 94722
- Checksum: 17CDC4DFF07AC039
- Sequence:
MDARGGGGRP GDSPGTTPAP GPPPPPPPPA PPQPQPPPAP PPNPTTPSHP ESADEPGPRA RLCSRDSACT PGAAKGGANG ECGRGEPQCS PEGPARGPKV SFSCRGAASG PSAAEEAGSE EAGPAGEPRG SQASFLQRQF GALLQPGVNK FSLRMFGSQK AVEREQERVK SAGAWIIHPY SDFRFYWDFT MLLFMVGNLI IIPVGITFFK DETTAPWIVF NVVSDTFFLM DLVLNFRTGI VIEDNTEIIL DPEKIKKKYL RTWFVVDFVS SIPVDYIFLI VEKGIDSEVY KTARALRIVR FTKILSLLRL LRLSRLIRYI HQWEEIFHMT YDLASAVMRI CNLISMMLLL CHWDGCLQFL VPMLQDFPSD CWVSINNMVN HSWSELYSFA LFKAMSHMLC IGYGRQAPES MTDIWLTMLS MIVGATCYAM FIGHATALIQ SLDSSRRQYQ EKYKQVEQYM SFHKLPADFR QKIHDYYEHR YQGKMFDEDS ILGELNGPLR EEIVNFNCRK LVASMPLFAN ADPNFVTAML TKLKFEVFQP GDYIIREGTI GKKMYFIQHG VVSVLTKGNK EMKLSDGSYF GEICLLTRGR RTASVRADTY CRLYSLSVDN FNEVLEEYPM MRRAFETVAI DRLDRIGKKN SILLHKVQHD LSSGVFNNQE NAIIQEIVKY DREMVQQAEL GQRVGLFPPP PPPQVTSAIA TLQQAVAMSF CPQVARPLVG PLALGSPRLV RRAPPGPLPP AASPGPPAAS PPAAPSSPRA PRTSPYGVPG SPATRVGPAL PARRLSRASR PLSASQPSLP HGVPAPSPAA SARPASSSTP RLGPAPTART AAPSPDRRDS ASPGAASGLD PLDSARSRLS SNL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.