Details for: Hcn3

Gene ID: 15168

Symbol: Hcn3

Ensembl ID: ENSMUSG00000028051

Description: hyperpolarization-activated, cyclic nucleotide-gated K+ 3

Associated with

Other Information

Genular Protein ID: 1114716192

Symbol: HCN3_MOUSE

Name: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3

UniProtKB Accession Codes:

O88705

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 3 ChiTaRS 1 ComplexPortal 1 DNASU 1 EMBL 3 Ensembl 1 ExpressionAtlas 1 GO 15 Gene3D 3 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 3 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9634236

Title: A family of hyperpolarization-activated cation channels.

PubMed ID: 9634236

DOI: 10.1038/31255

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9630217

Title: Identification of a gene encoding a hyperpolarization-activated 'pacemaker' channel of brain.

PubMed ID: 9630217

DOI: 10.1016/s0092-8674(00)81434-8

PubMed ID: 15923185

Title: The murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotides.

PubMed ID: 15923185

DOI: 10.1074/jbc.m502696200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23382386

Title: Up-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) by specific interaction with K+ channel tetramerization domain-containing protein 3 (KCTD3).

PubMed ID: 23382386

DOI: 10.1074/jbc.m112.434803

Sequence Information:

  • Length: 779
  • Mass: 86641
  • Checksum: D4FF151F174DECAE
  • Sequence:
    • MEEEARPAAG AGEAATPARE TPPAAPAQAR AASGGVPESA PEPKRRQLGT LLQPTVNKFS 
LRVFGSHKAV EIEQERVKSA GAWIIHPYSD FRFYWDLIML LLMVGNLIVL PVGITFFKEE 
NSPPWIVFNV LSDTFFLLDL VLNFRTGIVV EEGAEILLAP RAIRTRYLRT WFLVDLISSI 
PVDYIFLVVE LEPRLDAEVY KTARALRIVR FTKILSLLRL LRLSRLIRYI HQWEEIFHMT 
YDLASAVVRI FNLIGMMLLL CHWDGCLQFL VPMLQDFPSD CWVSMNRMVN HSWGRQYSHA 
LFKAMSHMLC IGYGQQAPVG MPDVWLTMLS MIVGATCYAM FIGHATALIQ SLDSSRRQYQ 
EKYKQVEQYM SFHKLPADTR QRIHEYYEHR YQGKMFDEES ILGELSEPLR EEIINFTCRG 
LVAHMPLFAH ADPSFVTAVL TKLRFEVFQP GDLVVREGSV GRKMYFIQHG LLSVLARGAR 
DTRLTDGSYF GEICLLTRGR RTASVRADTY CRLYSLSVDH FNAVLEEFPM MRRAFETVAM 
DRLRRIGKKN SILQRKRSEP SPGSSGGVME QHLVQHDRDM ARGVRGLAPG TGARLSGKPV 
LWEPLVHAPL QAAAVTSNVA IALTHQRGPL PLSPDSPATL LARSARRSAG SPASPLVPVR 
AGPLLARGPW ASTSRLPAPP ARTLHASLSR TGRSQVSLLG PPPGGGARRL GPRGRPLSAS 
QPSLPQRATG DGSPRRKGSG SERLPPSGLL AKPPGTVQPP RSSVPEPVTP RGPQISANM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.