Genular: Defining Cellular Identity and Function

Details for: Hcrt

Gene ID: 15171

Symbol: Hcrt

Ensembl ID: ENSMUSG00000045471

Description: hypocretin

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Orexin and neuropeptides ff and qrfp bind to their respective receptors
(R-MMU-389397)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Cytoplasmic vesicle
(GO:0031410)
Eating behavior
(GO:0042755)
Endoplasmic reticulum
(GO:0005783)
Excitatory postsynaptic potential
(GO:0060079)
Feeding behavior
(GO:0007631)
Negative regulation of dna replication
(GO:0008156)
Negative regulation of potassium ion transport
(GO:0043267)
Negative regulation of transmission of nerve impulse
(GO:0051970)
Neuropeptide hormone activity
(GO:0005184)
Neuropeptide signaling pathway
(GO:0007218)
Perinuclear region of cytoplasm
(GO:0048471)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Positive regulation of calcium ion transport
(GO:0051928)
Positive regulation of cold-induced thermogenesis
(GO:0120162)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of transmission of nerve impulse
(GO:0051971)
Protein kinase c-activating g protein-coupled receptor signaling pathway
(GO:0007205)
Regulation of neurotransmitter secretion
(GO:0046928)
Response to starvation
(GO:0042594)
Secretory granule
(GO:0030141)
Sleep
(GO:0030431)
Synapse
(GO:0045202)
Temperature homeostasis
(GO:0001659)
Type 1 orexin receptor binding
(GO:0031771)
Type 2 orexin receptor binding
(GO:0031772)

Other Information

Proteins

OREX_MOUSE

Genular Protein ID: 465235412

Symbol: OREX_MOUSE

Name: N/A

UniProtKB Accession Codes:

O55241

Database IDs:

Citations:

PubMed ID: 9491897

Title: Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

PubMed ID: 9491897

DOI: 10.1016/s0092-8674(00)80949-6

PubMed ID: 9419374

Title: The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.

PubMed ID: 9419374

DOI: 10.1073/pnas.95.1.322

PubMed ID: 11340621

Title: Hypocretin/orexin, sleep and narcolepsy.

PubMed ID: 11340621

DOI: 10.1002/bies.1058

PubMed ID: 11283317

Title: To eat or to sleep? Orexin in the regulation of feeding and wakefulness.

PubMed ID: 11283317

DOI: 10.1146/annurev.neuro.24.1.429

Sequence Information:

Length: 130
Mass: 13503
Checksum: D3C223F9EE835F1C
Sequence:

MNFPSTKVPW AAVTLLLLLL LPPALLSLGV DAQPLPDCCR QKTCSCRLYE LLHGAGNHAA 
GILTLGKRRP GPPGLQGRLQ RLLQANGNHA AGILTMGRRA GAELEPHPCS GRGCPTVTTT 
ALAPRGGSGV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hcrt

Associated with

Other Information

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. PubMed ID: 9491897

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. PubMed ID: 9419374

Hypocretin/orexin, sleep and narcolepsy. PubMed ID: 11340621

To eat or to sleep? Orexin in the regulation of feeding and wakefulness. PubMed ID: 11283317

Database document:

PubMed ID: 9491897

PubMed ID: 9419374

PubMed ID: 11340621

PubMed ID: 11283317