Genular: Defining Cellular Identity and Function

Details for: Hesx1

Gene ID: 15209

Symbol: Hesx1

Ensembl ID: ENSMUSG00000040726

Description: homeobox gene expressed in ES cells

Associated with

Brain development
(GO:0007420)
Camera-type eye development
(GO:0043010)
Canonical wnt signaling pathway
(GO:0060070)
Cellular response to cadmium ion
(GO:0071276)
Chromatin binding
(GO:0003682)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Erk1 and erk2 cascade
(GO:0070371)
Forebrain development
(GO:0030900)
Forebrain morphogenesis
(GO:0048853)
Gene expression
(GO:0010467)
Gonad development
(GO:0008406)
Leukemia inhibitory factor signaling pathway
(GO:0048861)
Multicellular organism development
(GO:0007275)
Multicellular organism growth
(GO:0035264)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nose development
(GO:0043584)
Nucleus
(GO:0005634)
Otic vesicle formation
(GO:0030916)
Pituitary gland development
(GO:0021983)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of embryonic development
(GO:0045995)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Stem cell differentiation
(GO:0048863)
Stem cell population maintenance
(GO:0019827)
Thyroid gland development
(GO:0030878)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Homeobox expressed in ES cells 1

Genular Protein ID: 3931103169

Symbol: HESX1_MOUSE

Name: Homeobox expressed in ES cells 1

UniProtKB Accession Codes:

Q61658 Q61047 Q8C477

Database IDs:

Citations:

PubMed ID: 7876132

Title: Sequence, genomic organization, and expression of the novel homeobox gene Hesx1.

PubMed ID: 7876132

DOI: 10.1074/jbc.270.8.3869

PubMed ID: 8565852

Title: Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke's pouch of the mouse embryo.

PubMed ID: 8565852

DOI: 10.1242/dev.122.1.41

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1360650

Title: HES-1, a novel homeobox gene expressed by murine embryonic stem cells, identifies a new class of homeobox genes.

PubMed ID: 1360650

DOI: 10.1093/nar/20.21.5840

PubMed ID: 9620767

Title: Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse.

PubMed ID: 9620767

DOI: 10.1038/477

Sequence Information:

Length: 185
Mass: 21504
Checksum: 5C18A524BF281246
Sequence:

MSPSLREGAQ LRESKPAPCS FSIESILGLD QKKDCTTSVR PHRPWTDTCG DSEKGGNPPL 
HAPDLPSETS FPCPVDHPRP EERAPKYENY FSASETRSLK RELSWYRGRR PRTAFTQNQV 
EVLENVFRVN CYPGIDIRED LAQKLNLEED RIQIWFQNRR AKMKRSRRES QFLMAKKPFN 
PDLLK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hesx1

Associated with

Other Information

Sequence, genomic organization, and expression of the novel homeobox gene Hesx1. PubMed ID: 7876132

Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke's pouch of the mouse embryo. PubMed ID: 8565852

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

HES-1, a novel homeobox gene expressed by murine embryonic stem cells, identifies a new class of homeobox genes. PubMed ID: 1360650

Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse. PubMed ID: 9620767