Hexa | ENSMUSG00000025232 | NCBI 15211

Details for: Hexa

Gene ID: 15211

Symbol: Hexa

Ensembl ID: ENSMUSG00000025232

Description: hexosaminidase A

Associated with

Chondroitin sulfate/dermatan sulfate metabolism
(R-MMU-1793185)
Cs/ds degradation
(R-MMU-2024101)
Glycosaminoglycan metabolism
(R-MMU-1630316)
Glycosphingolipid catabolism
(R-MMU-9840310)
Glycosphingolipid metabolism
(R-MMU-1660662)
Hyaluronan metabolism
(R-MMU-2142845)
Hyaluronan uptake and degradation
(R-MMU-2160916)
Keratan sulfate/keratin metabolism
(R-MMU-1638074)
Keratan sulfate degradation
(R-MMU-2022857)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Metabolism of lipids
(R-MMU-556833)
Sphingolipid metabolism
(R-MMU-428157)
Acetylglucosaminyltransferase activity
(GO:0008375)
Adult walking behavior
(GO:0007628)
Azurophil granule
(GO:0042582)
Beta-n-acetylhexosaminidase activity
(GO:0004563)
Beta-n-acetylhexosaminidase complex
(GO:1905379)
Carbohydrate metabolic process
(GO:0005975)
Cell morphogenesis involved in neuron differentiation
(GO:0048667)
Cytosol
(GO:0005829)
Dermatan sulfate catabolic process
(GO:0030209)
Ganglioside catabolic process
(GO:0006689)
Glycosaminoglycan biosynthetic process
(GO:0006024)
Glycosaminoglycan metabolic process
(GO:0030203)
Hyaluronan catabolic process
(GO:0030214)
Hydrolase activity
(GO:0016787)
Hydrolase activity, acting on glycosyl bonds
(GO:0016798)
Hydrolase activity, hydrolyzing o-glycosyl compounds
(GO:0004553)
Intracellular membrane-bounded organelle
(GO:0043231)
Lipid metabolic process
(GO:0006629)
Lipid storage
(GO:0019915)
Locomotory behavior
(GO:0007626)
Lysosomal lumen
(GO:0043202)
Lysosome
(GO:0005764)
Lysosome organization
(GO:0007040)
Maintenance of location in cell
(GO:0051651)
Membrane
(GO:0016020)
Metabolic process
(GO:0008152)
Myelination
(GO:0042552)
N-acetyl-beta-d-galactosaminidase activity
(GO:0102148)
Neuromuscular process controlling balance
(GO:0050885)
Neuromuscular process controlling posture
(GO:0050884)
Protein heterodimerization activity
(GO:0046982)
Sensory perception of sound
(GO:0007605)
Sexual reproduction
(GO:0019953)
Skeletal system development
(GO:0001501)

Other Information

Proteins

Beta-N-acetylhexosaminidase subunit alpha

Genular Protein ID: 4232368364

Symbol: HEXA_MOUSE

Name: Beta-N-acetylhexosaminidase subunit alpha

UniProtKB Accession Codes:

P29416 Q64246 Q91XG3

Database IDs:

Citations:

PubMed ID: 1379046

Title: Cloning and sequence analysis of a cDNA encoding the alpha-subunit of mouse beta-N-acetylhexosaminidase and comparison with the human enzyme.

PubMed ID: 1379046

DOI: 10.1042/bj2850593

PubMed ID: 7833835

Title: Organization of the gene for the alpha-subunit of mouse beta-N-acetylhexosaminidase (HEXa).

PubMed ID: 7833835

PubMed ID: 7959736

Title: Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb.

PubMed ID: 7959736

DOI: 10.1006/geno.1994.1318

PubMed ID: 7896264

Title: Structural organization, sequence, and expression of the mouse HEXA gene encoding the alpha subunit of hexosaminidase A.

PubMed ID: 7896264

DOI: 10.1006/geno.1994.1587

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 528
Mass: 60613
Checksum: 95DEA72D767094EF
Sequence:

MAGCRLWVSL LLAAALACLA TALWPWPQYI QTYHRRYTLY PNNFQFRYHV SSAAQAGCVV 
LDEAFRRYRN LLFGSGSWPR PSFSNKQQTL GKNILVVSVV TAECNEFPNL ESVENYTLTI 
NDDQCLLASE TVWGALRGLE TFSQLVWKSA EGTFFINKTK IKDFPRFPHR GVLLDTSRHY 
LPLSSILDTL DVMAYNKFNV FHWHLVDDSS FPYESFTFPE LTRKGSFNPV THIYTAQDVK 
EVIEYARLRG IRVLAEFDTP GHTLSWGPGA PGLLTPCYSG SHLSGTFGPV NPSLNSTYDF 
MSTLFLEISS VFPDFYLHLG GDEVDFTCWK SNPNIQAFMK KKGFTDFKQL ESFYIQTLLD 
IVSDYDKGYV VWQEVFDNKV KVRPDTIIQV WREEMPVEYM LEMQDITRAG FRALLSAPWY 
LNRVKYGPDW KDMYKVEPLA FHGTPEQKAL VIGGEACMWG EYVDSTNLVP RLWPRAGAVA 
ERLWSSNLTT NIDFAFKRLS HFRCELVRRG IQAQPISVGY CEQEFEQT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hexa

Associated with

Other Information

Cloning and sequence analysis of a cDNA encoding the alpha-subunit of mouse beta-N-acetylhexosaminidase and comparison with the human enzyme. PubMed ID: 1379046

Organization of the gene for the alpha-subunit of mouse beta-N-acetylhexosaminidase (HEXa). PubMed ID: 7833835

Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb. PubMed ID: 7959736

Structural organization, sequence, and expression of the mouse HEXA gene encoding the alpha subunit of hexosaminidase A. PubMed ID: 7896264

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079