Genular: Defining Cellular Identity and Function

Details for: Hexb

Gene ID: 15212

Symbol: Hexb

Ensembl ID: ENSMUSG00000021665

Description: hexosaminidase B

Associated with

Chondroitin sulfate/dermatan sulfate metabolism
(R-MMU-1793185)
Cs/ds degradation
(R-MMU-2024101)
Glycosaminoglycan metabolism
(R-MMU-1630316)
Glycosphingolipid catabolism
(R-MMU-9840310)
Glycosphingolipid metabolism
(R-MMU-1660662)
Hyaluronan metabolism
(R-MMU-2142845)
Hyaluronan uptake and degradation
(R-MMU-2160916)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Keratan sulfate/keratin metabolism
(R-MMU-1638074)
Keratan sulfate degradation
(R-MMU-2022857)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Metabolism of lipids
(R-MMU-556833)
Neutrophil degranulation
(R-MMU-6798695)
Sphingolipid metabolism
(R-MMU-428157)
Acetylglucosaminyltransferase activity
(GO:0008375)
Acrosomal vesicle
(GO:0001669)
Astrocyte cell migration
(GO:0043615)
Azurophil granule
(GO:0042582)
Beta-n-acetylglucosaminidase activity
(GO:0016231)
Beta-n-acetylhexosaminidase activity
(GO:0004563)
Beta-n-acetylhexosaminidase complex
(GO:1905379)
Carbohydrate binding
(GO:0030246)
Carbohydrate metabolic process
(GO:0005975)
Chondroitin sulfate catabolic process
(GO:0030207)
Cortical granule
(GO:0060473)
Cytoplasmic vesicle
(GO:0031410)
Dermatan sulfate catabolic process
(GO:0030209)
Extracellular space
(GO:0005615)
Ganglioside catabolic process
(GO:0006689)
Glycosaminoglycan metabolic process
(GO:0030203)
Glycosphingolipid metabolic process
(GO:0006687)
Hexosaminidase activity
(GO:0015929)
Hyaluronan catabolic process
(GO:0030214)
Hydrolase activity
(GO:0016787)
Hydrolase activity, acting on glycosyl bonds
(GO:0016798)
Hydrolase activity, hydrolyzing o-glycosyl compounds
(GO:0004553)
Identical protein binding
(GO:0042802)
Intracellular calcium ion homeostasis
(GO:0006874)
Lipid metabolic process
(GO:0006629)
Lipid storage
(GO:0019915)
Locomotory behavior
(GO:0007626)
Lysosomal lumen
(GO:0043202)
Lysosome
(GO:0005764)
Lysosome organization
(GO:0007040)
Maintenance of location in cell
(GO:0051651)
Male courtship behavior
(GO:0008049)
Membrane
(GO:0016020)
Metabolic process
(GO:0008152)
Myelination
(GO:0042552)
N-acetyl-beta-d-galactosaminidase activity
(GO:0102148)
N-acetylglucosamine metabolic process
(GO:0006044)
Neuromuscular process
(GO:0050905)
Neuromuscular process controlling balance
(GO:0050885)
Neuron cellular homeostasis
(GO:0070050)
Oligosaccharide catabolic process
(GO:0009313)
Oogenesis
(GO:0048477)
Penetration of zona pellucida
(GO:0007341)
Phospholipid biosynthetic process
(GO:0008654)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-containing complex binding
(GO:0044877)
Protein metabolic process
(GO:0019538)
Regulation of cell shape
(GO:0008360)
Regulation of cellular metabolic process
(GO:0031323)
Sensory perception of sound
(GO:0007605)
Sexual reproduction
(GO:0019953)
Single fertilization
(GO:0007338)
Skeletal system development
(GO:0001501)

Other Information

Proteins

Beta-N-acetylhexosaminidase subunit beta

Genular Protein ID: 2354616255

Symbol: HEXB_MOUSE

Name: Beta-N-acetylhexosaminidase subunit beta

UniProtKB Accession Codes:

P20060

Database IDs:

Citations:

PubMed ID: 2971567

Title: Cloning and sequence analysis of a cDNA encoding the beta-subunit of mouse beta-hexosaminidase.

PubMed ID: 2971567

DOI: 10.1016/0014-5793(88)80199-6

PubMed ID: 7959736

Title: Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb.

PubMed ID: 7959736

DOI: 10.1006/geno.1994.1318

PubMed ID: 7918686

Title: Characterization of the murine beta-hexosaminidase (HEXB) gene.

PubMed ID: 7918686

DOI: 10.1016/0925-4439(94)90110-4

PubMed ID: 8253842

Title: Egg cortical granule N-acetylglucosaminidase is required for the mouse zona block to polyspermy.

PubMed ID: 8253842

DOI: 10.1083/jcb.123.6.1431

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 536
Mass: 61116
Checksum: 579BBEEE9CB508BC
Sequence:

MPQSPRSAPG LLLLQALVSL VSLALVAPAR LQPALWPFPR SVQMFPRLLY ISAEDFSIDH 
SPNSTAGPSC SLLQEAFRRY YNYVFGFYKR HHGPARFRAE PQLQKLLVSI TLESECESFP 
SLSSDETYSL LVQEPVAVLK ANSVWGALRG LETFSQLVYQ DSFGTFTINE SSIADSPRFP 
HRGILIDTSR HFLPVKTILK TLDAMAFNKF NVLHWHIVDD QSFPYQSTTF PELSNKGSYS 
LSHVYTPNDV RMVLEYARLR GIRVIPEFDT PGHTQSWGKG QKNLLTPCYN QKTKTQVFGP 
VDPTVNTTYA FFNTFFKEIS SVFPDQFIHL GGDEVEFQCW ASNPNIQGFM KRKGFGSDFR 
RLESFYIKKI LEIISSLKKN SIVWQEVFDD KVELQPGTVV EVWKSEHYSY ELKQVTGSGF 
PAILSAPWYL DLISYGQDWK NYYKVEPLNF EGSEKQKQLV IGGEACLWGE FVDATNLTPR 
LWPRASAVGE RLWSPKTVTD LENAYKRLAV HRCRMVSRGI AAQPLYTGYC NYENKI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hexb

Associated with

Other Information

Cloning and sequence analysis of a cDNA encoding the beta-subunit of mouse beta-hexosaminidase. PubMed ID: 2971567

Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb. PubMed ID: 7959736

Characterization of the murine beta-hexosaminidase (HEXB) gene. PubMed ID: 7918686