Details for: Hey1

Gene ID: 15213

Symbol: Hey1

Ensembl ID: ENSMUSG00000040289

Description: hairy/enhancer-of-split related with YRPW motif 1

Associated with

  • Anterior/posterior axis specification
    (GO:0009948)
  • Anterior/posterior pattern specification
    (GO:0009952)
  • Aortic valve morphogenesis
    (GO:0003180)
  • Arterial endothelial cell differentiation
    (GO:0060842)
  • Artery development
    (GO:0060840)
  • Atrioventricular valve formation
    (GO:0003190)
  • Atrioventricular valve morphogenesis
    (GO:0003181)
  • Blood vessel development
    (GO:0001568)
  • Blood vessel endothelial cell differentiation
    (GO:0060837)
  • Cardiac epithelial to mesenchymal transition
    (GO:0060317)
  • Cardiac septum morphogenesis
    (GO:0060411)
  • Cardiac ventricle morphogenesis
    (GO:0003208)
  • Circulatory system development
    (GO:0072359)
  • Cis-regulatory region sequence-specific dna binding
    (GO:0000987)
  • Comma-shaped body morphogenesis
    (GO:0072049)
  • Cytoplasm
    (GO:0005737)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Dorsal aorta morphogenesis
    (GO:0035912)
  • Endocardial cushion morphogenesis
    (GO:0003203)
  • Endocardial cushion to mesenchymal transition involved in heart valve formation
    (GO:0003199)
  • Epithelial to mesenchymal transition involved in endocardial cushion formation
    (GO:0003198)
  • Establishment of epithelial cell polarity
    (GO:0090162)
  • Identical protein binding
    (GO:0042802)
  • Inner ear receptor cell stereocilium organization
    (GO:0060122)
  • Labyrinthine layer blood vessel development
    (GO:0060716)
  • Mesenchymal cell development
    (GO:0014031)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of biomineral tissue development
    (GO:0070168)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of gene expression
    (GO:0010629)
  • Negative regulation of neuron differentiation
    (GO:0045665)
  • Negative regulation of notch signaling pathway
    (GO:0045746)
  • Negative regulation of smooth muscle cell differentiation
    (GO:0051151)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Notch signaling pathway
    (GO:0007219)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Osteoblast development
    (GO:0002076)
  • Outflow tract morphogenesis
    (GO:0003151)
  • Positive regulation of osteoblast differentiation
    (GO:0045669)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Protein dimerization activity
    (GO:0046983)
  • Pulmonary valve morphogenesis
    (GO:0003184)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of epithelial cell proliferation
    (GO:0050678)
  • Regulation of inner ear auditory receptor cell differentiation
    (GO:0045607)
  • Regulation of neurogenesis
    (GO:0050767)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Regulation of vasculogenesis
    (GO:2001212)
  • Renal vesicle development
    (GO:0072087)
  • Rna polymerase ii-specific dna-binding transcription factor binding
    (GO:0061629)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • S-shaped body morphogenesis
    (GO:0072050)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Umbilical cord morphogenesis
    (GO:0036304)
  • Ureteric bud morphogenesis
    (GO:0060675)
  • Vasculogenesis
    (GO:0001570)
  • Ventricular septum morphogenesis
    (GO:0060412)
  • Ventricular trabecula myocardium morphogenesis
    (GO:0003222)

Other Information

Genular Protein ID: 4006895023

Symbol: Q9QUM5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9QUM5

Database IDs:

AGR 1 ARBA 5 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 14 Ensembl 2 GO 8 Gene3D 2 GeneTree 1 HOGENOM 1 InterPro 3 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 4 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10588864

Title: HRT1, HRT2 and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic and pharyngeal arch segments.

PubMed ID: 10588864

DOI: 10.1006/dbio.1999.9454

PubMed ID: 10415358

Title: Hey genes: a novel subfamily of hairy- and enhancer of split related genes specifically expressed during mouse embryogenesis.

PubMed ID: 10415358

DOI: 10.1016/S0925-4773(99)00080-5

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 10692439

Title: Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system.

PubMed ID: 10692439

DOI: 10.1074/jbc.275.9.6381

PubMed ID: 11486044

Title: HERP, a new primary target of Notch regulated by ligand binding.

PubMed ID: 11486044

DOI: 10.1128/MCB.21.17.6071-6079.2001

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 299
  • Mass: 32106
  • Checksum: 77110233BC98A1AE
  • Sequence:
    • MKRAHPDYSS SDSELDETIE VEKESADENG NLSSALCSMS PTTSSQVLAR KRRRGIIEKR 
RRDRINNSLS ELRRLVPSAF EKQGSAKLEK AEILQMTVDH LKMLHTAGGK GYFDAHALAM 
DYRSLGFREC LAEVARYLSI IEGLDASDPL RVRLVSHLNN YASQREAASG AHGGLGHIPW 
GSAFGHHPHI AHPLLLPQNG HGNAGTAASP TEPHHQGRLA SAHPEAPALR APPSGGLGPV 
LPVVTSASKL SPPLLSSVAS LSAFPFSFSS FHLLSPSTPT QAANLGKPYR PWGTEIGAF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.