Details for: Foxd3

Gene ID: 15221

Symbol: Foxd3

Ensembl ID: ENSMUSG00000067261

Description: forkhead box D3

Associated with

  • Anatomical structure morphogenesis
    (GO:0009653)
  • Cell differentiation
    (GO:0030154)
  • Cellular response to leukemia inhibitory factor
    (GO:1990830)
  • Chromatin
    (GO:0000785)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna-templated transcription
    (GO:0006351)
  • Dna binding
    (GO:0003677)
  • Double-stranded dna binding
    (GO:0003690)
  • Embryonic placenta development
    (GO:0001892)
  • In utero embryonic development
    (GO:0001701)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Transcription cis-regulatory region binding
    (GO:0000976)
  • Transcription regulator complex
    (GO:0005667)
  • Trophectodermal cell differentiation
    (GO:0001829)

Other Information

Genular Protein ID: 3660699957

Symbol: FOXD3_MOUSE

Name: Forkhead box protein D3

UniProtKB Accession Codes:

Q61060

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 GO 22 Gene3D 1 InParanoid 1 InterPro 6 KEGG 1 MGI 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UniProtKB 1 eggNOG 1

Citations:

PubMed ID: 8798505

Title: Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells.

PubMed ID: 8798505

DOI: 10.1074/jbc.271.38.23126

PubMed ID: 9767163

Title: The winged helix transcription factor Hfh2 is expressed in neural crest and spinal cord during mouse development.

PubMed ID: 9767163

DOI: 10.1016/s0925-4773(98)00105-1

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 12381664

Title: Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo.

PubMed ID: 12381664

DOI: 10.1101/gad.1020502

PubMed ID: 11684651

Title: The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate.

PubMed ID: 11684651

DOI: 10.1242/dev.128.21.4127

Sequence Information:

  • Length: 465
  • Mass: 46345
  • Checksum: 7277EB2EE2C8E0C2
  • Sequence:
    • MTLSGSGSAS DMSGQTVLTA EDVDIDVVGE GDDGLEEKDS DAGCDSPAGP PDLRLDEADE 
GPPVSAHHGQ SQPQALALPT EATGPGNDTG APEADGCKGG EDAVTGGGGP GAGSGATGGL 
TPNKPKNSLV KPPYSYIALI TMAILQSPQK KLTLSGICEF ISNRFPYYRE KFPAWQNSIR 
HNLSLNDCFV KIPREPGNPG KGNYWTLDPQ SEDMFDNGSF LRRRKRFKRH QQEHLREQTA 
LMMQSFGAYS LAAAAGAGPY GLHPAAAAGA YSHPAAAAAA AAAAALQYPY ALPPVAPVLP 
PAVPLLPSGE LGRKAAAFGS QLGPSLQLQL NTLGAAAAAA GTAGAAGTTS LIKSEPSARP 
SFSIENIIGA GSAAPGGSAG GGGSGGGAGG GGGSGGGGGA QSFLRPPGTV QSAALMATHQ 
PLSLSRTTAT IAPILSVPLS GQFLQPAASA AAAAAAAVQA KWPAQ

Genular Protein ID: 520035074

Symbol: A2BDY3_MOUSE

Name: N/A

UniProtKB Accession Codes:

A2BDY3

Database IDs:

AGR 1 ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 Ensembl 2 GO 5 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InterPro 6 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 469
  • Mass: 46818
  • Checksum: 95E71211C79FAB03
  • Sequence:
    • MTLSGSGSAS DMSGQTVLTA EDVDIDVVGE GDDGLEEKDS DAGCDSPAGP PDLRLDEADE 
GPPVSAHHGQ SQPQALALPT EATGPGNDTG APEADGCKGG EDAVTGGGGP GAGSGATGGL 
TPNKPKNSLV KPPYSYIALI TMAILQSPQK KLTLSGICEF ISNRFPYYRE KFPAWQNSIR 
HNLSLNDCFV KIPREPGNPG KGNYWTLDPQ SEDMFDNGSF LRRRKRFKRH QQEHLREQTA 
LMMQSFGAYS LAAAAGAGPY GRPYGLHPAA AAGAYSHPAA AAAAAAAAAL QYPYALPPVA 
PVLPPAVPLL PSGELGRKAA AFGSQLGPSL QLQLNTLGAA AAAAGTAGAA GTTSLIKSEP 
SARPSFSIEN IIGAGSAAPG GSAGGGGSGG GAGGGGGSGG GGGAQSFLRP PGTVQSAALM 
ATHQPLSLSR TTATIAPILS VPLSGQFLQP AASAAAAAAA AVQAKWPAQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.