Details for: Foxj1

Gene ID: 15223

Symbol: Foxj1

Ensembl ID: ENSMUSG00000034227

Description: forkhead box J1

Associated with

  • Actin cytoskeleton organization
    (GO:0030036)
  • Activation of gtpase activity
    (GO:0090630)
  • Axoneme assembly
    (GO:0035082)
  • Brain development
    (GO:0007420)
  • Cell maturation
    (GO:0048469)
  • Cell projection organization
    (GO:0030030)
  • Central tolerance induction
    (GO:0002508)
  • Ciliary basal body organization
    (GO:0032053)
  • Cilium assembly
    (GO:0060271)
  • Determination of left/right symmetry
    (GO:0007368)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Epithelium development
    (GO:0060429)
  • Establishment of apical/basal cell polarity
    (GO:0035089)
  • Heart development
    (GO:0007507)
  • Humoral immune response
    (GO:0006959)
  • Left/right pattern formation
    (GO:0060972)
  • Leukocyte migration
    (GO:0050900)
  • Motile cilium assembly
    (GO:0044458)
  • Negative regulation of b cell activation
    (GO:0050869)
  • Negative regulation of germinal center formation
    (GO:0002635)
  • Negative regulation of humoral immune response mediated by circulating immunoglobulin
    (GO:0002924)
  • Negative regulation of interleukin-6 production
    (GO:0032715)
  • Negative regulation of nf-kappab transcription factor activity
    (GO:0032088)
  • Negative regulation of t cell differentiation in thymus
    (GO:0033085)
  • Negative regulation of t cell proliferation
    (GO:0042130)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Positive regulation of central b cell tolerance induction
    (GO:0002897)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of lung ciliated cell differentiation
    (GO:1901248)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein localization
    (GO:0008104)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of epithelial cell differentiation
    (GO:0030856)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)
  • Transcription cis-regulatory region binding
    (GO:0000976)

Other Information

Genular Protein ID: 4246602857

Symbol: FOXJ1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q61660 Q3US42

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 1 GO 39 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 7683413

Title: Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.

PubMed ID: 7683413

DOI: 10.1073/pnas.90.9.3948

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 9096351

Title: The winged helix transcription factor HFH-4 is expressed during choroid plexus epithelial development in the mouse embryo.

PubMed ID: 9096351

DOI: 10.1073/pnas.94.7.3094

PubMed ID: 9739041

Title: Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry.

PubMed ID: 9739041

DOI: 10.1172/jci4786

PubMed ID: 10873152

Title: Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null mice.

PubMed ID: 10873152

DOI: 10.1165/ajrcmb.23.1.4070

PubMed ID: 14996907

Title: Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells.

PubMed ID: 14996907

DOI: 10.1242/jcs.00978

PubMed ID: 22357932

Title: Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.

PubMed ID: 22357932

DOI: 10.1242/dev.072728

PubMed ID: 27965440

Title: CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility.

PubMed ID: 27965440

DOI: 10.1242/dev.139626

PubMed ID: 27914912

Title: Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse.

PubMed ID: 27914912

DOI: 10.1016/j.ydbio.2016.11.019

PubMed ID: 28666954

Title: 1700012B09Rik, a FOXJ1 effector gene active in ciliated tissues of the mouse but not essential for motile ciliogenesis.

PubMed ID: 28666954

DOI: 10.1016/j.ydbio.2017.06.027

Sequence Information:

  • Length: 421
  • Mass: 45474
  • Checksum: B5EB01D747672DFA
  • Sequence:
    • MAESWLRLCG AGPGEEAGPE GGMEEPDALD DSLTSLQWLQ EFSILNAKAP TLPPGGTDPH 
GYHQVPGLVA PGSPLAADPA CLGQPHTPGK PTSSCTSRSA PPGLQAPPPD DVDYATNPHV 
KPPYSYATLI CMAMQASKAT KITLSAIYKW ITDNFCYFRH ADPTWQNSIR HNLSLNKCFI 
KVPREKDEPG KGGFWRIDPQ YAERLLSGAF KKRRLPPVHI HPAFARQASQ EPSAAPWGGP 
LTVNREAQQL LQEFEEATGE GGWGTGEGRL GHKRKQPLPK RVAKVLRPPS TLLLTQEEQG 
ELEPLKGNFD WEAIFEAGAL GEELSSLEGL ELSPPLSPSS HGDVDLTVHG RHINCPATWG 
PPAEQAADSL DFDETFLATS FLQHPWDESG SGCLPPEPIF EAGDATLAAD LQDWASVGAF 
L

Genular Protein ID: 32404375

Symbol: Q640Q8_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q640Q8

Database IDs:

AGR 1 ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 1 Genevisible 1 InterPro 7 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 1 Pfam 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 421
  • Mass: 45460
  • Checksum: B5EB01D0A0F953FA
  • Sequence:
    • MAESWLRLCG AGPGEEAGPE GGMEEPDALD DSLTSLQWLQ EFSILNAKAP TLPPGGTDPH 
GYHQVPGLVA PGSPLAADPA CLGQPHTPGK PTSSCTSRSA PPGLQAPPPD DVDYATNPHV 
KPPYSYATLI CMAMQASKAT KITLSAIYKW ITDNFCYFRH ADPTWQNSIR HNLSLNKCFI 
KVPREKDEPG KGGFWRIDPQ YAERLLSGAF KKRRLPPVHI HPAFARQASQ EPSAAPWGGP 
LTVNREAQQL LQEFEEATGE GGWGTGEGRL GHKRKQPLPK RVAKVLRPPS TLLLTQEEQG 
ELEPLKGNFD WEAIFEAGAL GEELSSLEGL ELSPPLSPSS HGDVDLTVHG RHINCPATWG 
PPAEQAADSL DFDETFLGTS FLQHPWDESG SGCLPPEPIF EAGDATLAAD LQDWASVGAF 
L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.