Details for: CX3CR1

Gene ID: 1524

Symbol: CX3CR1

Ensembl ID: ENSG00000168329

Description: C-X3-C motif chemokine receptor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 41.8528
    Cell Significance Index: -6.5100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 14.3472
    Cell Significance Index: -7.3800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 5.2557
    Cell Significance Index: -6.4800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 3.9024
    Cell Significance Index: 97.5500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 3.2304
    Cell Significance Index: 49.9800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 3.2281
    Cell Significance Index: 197.9100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.4074
    Cell Significance Index: 52.1600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.8430
    Cell Significance Index: 59.0300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 1.7972
    Cell Significance Index: -5.5200
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.4925
    Cell Significance Index: 15.8800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 1.2336
    Cell Significance Index: 18.5900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.2111
    Cell Significance Index: 54.9000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.9428
    Cell Significance Index: 179.4300
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.7231
    Cell Significance Index: 8.6900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5751
    Cell Significance Index: 56.9000
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 0.5599
    Cell Significance Index: 4.3200
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.5411
    Cell Significance Index: 5.9100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5089
    Cell Significance Index: 459.5200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4562
    Cell Significance Index: 9.7200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3428
    Cell Significance Index: 37.2900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3170
    Cell Significance Index: 51.5600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2638
    Cell Significance Index: 15.8400
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.2043
    Cell Significance Index: 1.6600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1317
    Cell Significance Index: 9.1100
  • Cell Name: activated type II NK T cell (CL0000931)
    Fold Change: 0.0312
    Cell Significance Index: 0.0800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0031
    Cell Significance Index: -5.8500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0054
    Cell Significance Index: -10.0400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0060
    Cell Significance Index: -0.2100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0062
    Cell Significance Index: -0.1800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0065
    Cell Significance Index: -10.0400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0075
    Cell Significance Index: -10.2600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0077
    Cell Significance Index: -5.8400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0088
    Cell Significance Index: -6.5000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0099
    Cell Significance Index: -4.3900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0108
    Cell Significance Index: -5.8900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0109
    Cell Significance Index: -7.9600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0111
    Cell Significance Index: -6.2500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0120
    Cell Significance Index: -7.6400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0143
    Cell Significance Index: -5.1200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0176
    Cell Significance Index: -8.0000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0198
    Cell Significance Index: -5.7000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0245
    Cell Significance Index: -2.5000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0247
    Cell Significance Index: -4.9500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0276
    Cell Significance Index: -5.4700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0311
    Cell Significance Index: -6.5600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0319
    Cell Significance Index: -0.5900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0409
    Cell Significance Index: -6.9900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0410
    Cell Significance Index: -7.4000
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0417
    Cell Significance Index: -0.6100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0453
    Cell Significance Index: -6.2200
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: -0.0481
    Cell Significance Index: -0.2000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0508
    Cell Significance Index: -6.5600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0515
    Cell Significance Index: -7.4900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0578
    Cell Significance Index: -4.0900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0578
    Cell Significance Index: -7.4100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0586
    Cell Significance Index: -6.9100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0600
    Cell Significance Index: -2.8200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0603
    Cell Significance Index: -1.5500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0608
    Cell Significance Index: -7.4800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0619
    Cell Significance Index: -1.2900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0625
    Cell Significance Index: -6.5100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0627
    Cell Significance Index: -2.5700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0638
    Cell Significance Index: -7.3100
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0655
    Cell Significance Index: -0.7700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0685
    Cell Significance Index: -2.9800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0719
    Cell Significance Index: -2.0100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0879
    Cell Significance Index: -6.5500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0898
    Cell Significance Index: -5.5200
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0916
    Cell Significance Index: -1.5600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0933
    Cell Significance Index: -7.1600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0953
    Cell Significance Index: -2.5500
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.0988
    Cell Significance Index: -0.8800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0998
    Cell Significance Index: -6.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1105
    Cell Significance Index: -7.1300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1114
    Cell Significance Index: -5.6300
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1148
    Cell Significance Index: -2.7800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1410
    Cell Significance Index: -7.9100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1473
    Cell Significance Index: -7.6500
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.1481
    Cell Significance Index: -2.1500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1625
    Cell Significance Index: -8.5300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1736
    Cell Significance Index: -6.0800
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1785
    Cell Significance Index: -3.4900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1795
    Cell Significance Index: -2.5700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1811
    Cell Significance Index: -8.0100
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1874
    Cell Significance Index: -2.4900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1951
    Cell Significance Index: -5.7300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2004
    Cell Significance Index: -6.5600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2047
    Cell Significance Index: -6.5200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2150
    Cell Significance Index: -8.1400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2185
    Cell Significance Index: -8.0200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2198
    Cell Significance Index: -10.2500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2316
    Cell Significance Index: -6.6400
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.2390
    Cell Significance Index: -2.0200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2412
    Cell Significance Index: -6.4400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2460
    Cell Significance Index: -7.0200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2466
    Cell Significance Index: -6.4900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2489
    Cell Significance Index: -6.6700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2490
    Cell Significance Index: -6.3600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2530
    Cell Significance Index: -6.3100
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.2619
    Cell Significance Index: -6.5300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Ligand specificity:** CX3CR1 is specifically activated by its ligand, CX3CL1, which is primarily expressed on microglial cells and other immune cells. 2. **G-protein coupled receptor activity:** CX3CR1 is a G-protein coupled receptor (GPCR) that activates downstream signaling pathways upon ligand binding. 3. **Chemotaxis and adhesion:** CX3CR1 mediates chemotaxis and adhesion of immune cells, including microglial cells, to CX3CL1. 4. **Survival and migration:** CX3CR1 signaling regulates the survival and migration of immune cells, including microglial cells and other immune cells. 5. **Neurodevelopmental roles:** CX3CR1 is involved in the regulation of neurodevelopment, including the formation of dendritic trees and synaptic maturation. **Pathways and Functions:** CX3CR1 signaling activates various downstream pathways, including: 1. **Calcium-mediated signaling:** CX3CR1 triggers the activation of calcium-dependent signaling pathways, which regulate cellular processes such as chemotaxis and adhesion. 2. **Autocrine signaling:** CX3CR1 can also act as an autocrine receptor, promoting the survival and proliferation of immune cells. 3. **Phospholipase C-activating signaling pathway:** CX3CR1 activates the phospholipase C-activating GPCR signaling pathway, which regulates the production of inositol trisphosphate and diacylglycerol. 4. **NF-κB signaling pathway:** CX3CR1 can also activate the NF-κB signaling pathway, which regulates the expression of genes involved in immune responses and inflammation. **Clinical Significance:** CX3CR1 has been implicated in various diseases, including: 1. **Multiple sclerosis:** CX3CR1 has been shown to play a critical role in the pathogenesis of multiple sclerosis, a demyelinating disease of the central nervous system. 2. **Alzheimer's disease:** CX3CR1 has been implicated in the regulation of neuroinflammation and neuronal loss in Alzheimer's disease. 3. **Seizure disorders:** CX3CR1 has been shown to regulate the excitability of neurons and the formation of synapses, making it a potential target for the treatment of seizure disorders. 4. **Inflammatory diseases:** CX3CR1 has been implicated in the regulation of inflammatory responses, making it a potential target for the treatment of inflammatory diseases. In conclusion, CX3CR1 is a complex receptor that plays a multifaceted role in the regulation of immune responses, neurodevelopment, and tissue homeostasis. Further research is necessary to fully elucidate the mechanisms by which CX3CR1 regulates these processes and to explore its therapeutic potential in various diseases.

Genular Protein ID: 402047493

Symbol: CX3C1_HUMAN

Name: G-protein coupled receptor 13

UniProtKB Accession Codes:

P49238 A0N0N6 B2R5Z4 J3KP17

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EMDB 1 Ensembl 4 ExpressionAtlas 1 GO 66 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 4 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 4 RefSeq 4 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7590284

Title: The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissues.

PubMed ID: 7590284

DOI: 10.1016/0378-1119(95)00336-5

PubMed ID: 7646814

Title: Cloning, chromosomal localization, and RNA expression of a human beta chemokine receptor-like gene.

PubMed ID: 7646814

DOI: 10.1089/dna.1995.14.673

PubMed ID: 12551893

Title: Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus.

PubMed ID: 12551893

DOI: 10.1074/jbc.m211422200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9390561

Title: Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion.

PubMed ID: 9390561

DOI: 10.1016/s0092-8674(00)80438-9

PubMed ID: 9782118

Title: Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow.

PubMed ID: 9782118

DOI: 10.1084/jem.188.8.1413

PubMed ID: 11477410

Title: CX3C chemokine mimicry by respiratory syncytial virus G glycoprotein.

PubMed ID: 11477410

DOI: 10.1038/90675

PubMed ID: 12055230

Title: Dual functions of fractalkine/CX3C ligand 1 in trafficking of perforin+/granzyme B+ cytotoxic effector lymphocytes that are defined by CX3CR1 expression.

PubMed ID: 12055230

DOI: 10.4049/jimmunol.168.12.6173

PubMed ID: 14607932

Title: Two novel fully functional isoforms of CX3CR1 are potent HIV coreceptors.

PubMed ID: 14607932

DOI: 10.4049/jimmunol.171.10.5305

PubMed ID: 9726990

Title: Identification of CX3CR1. A chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1.

PubMed ID: 9726990

DOI: 10.1074/jbc.273.37.23799

PubMed ID: 14581400

Title: Smooth muscle cells in human atherosclerotic plaques express the fractalkine receptor CX3CR1 and undergo chemotaxis to the CX3C chemokine fractalkine (CX3CL1).

PubMed ID: 14581400

DOI: 10.1161/01.cir.0000097119.57756.ef

PubMed ID: 18971423

Title: CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival.

PubMed ID: 18971423

DOI: 10.1182/blood-2008-07-170787

PubMed ID: 20974991

Title: Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1.

PubMed ID: 20974991

DOI: 10.4049/jimmunol.0904126

PubMed ID: 23125415

Title: Integrins alphavbeta3 and alpha4beta1 act as coreceptors for fractalkine, and the integrin-binding defective mutant of fractalkine is an antagonist of CX3CR1.

PubMed ID: 23125415

DOI: 10.4049/jimmunol.1200889

PubMed ID: 28791023

Title: TGF-beta1 downregulates the expression of CX3CR1 by inducing miR-27a-5p in primary human NK cells.

PubMed ID: 28791023

DOI: 10.3389/fimmu.2017.00868

PubMed ID: 29326275

Title: CX3CR1+ mononuclear phagocytes control immunity to intestinal fungi.

PubMed ID: 29326275

DOI: 10.1126/science.aao1503

PubMed ID: 10731151

Title: Rapid progression to AIDS in HIV+ individuals with a structural variant of the chemokine receptor CX3CR1.

PubMed ID: 10731151

DOI: 10.1126/science.287.5461.2274

PubMed ID: 11264153

Title: Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor for coronary artery disease.

PubMed ID: 11264153

DOI: 10.1182/blood.v97.7.1925

PubMed ID: 15208270

Title: The involvement of sequence variation and expression of CX3CR1 in the pathogenesis of age-related macular degeneration.

PubMed ID: 15208270

DOI: 10.1096/fj.04-1862fje

PubMed ID: 17909628

Title: CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.

PubMed ID: 17909628

DOI: 10.1172/jci31692

Sequence Information:

  • Length: 355
  • Mass: 40396
  • Checksum: C59DC5F4C4312F22
  • Sequence:
    • MDQFPESVTE NFEYDDLAEA CYIGDIVVFG TVFLSIFYSV IFAIGLVGNL LVVFALTNSK 
KPKSVTDIYL LNLALSDLLF VATLPFWTHY LINEKGLHNA MCKFTTAFFF IGFFGSIFFI 
TVISIDRYLA IVLAANSMNN RTVQHGVTIS LGVWAAAILV AAPQFMFTKQ KENECLGDYP 
EVLQEIWPVL RNVETNFLGF LLPLLIMSYC YFRIIQTLFS CKNHKKAKAI KLILLVVIVF 
FLFWTPYNVM IFLETLKLYD FFPSCDMRKD LRLALSVTET VAFSHCCLNP LIYAFAGEKF 
RRYLYHLYGK CLAVLCGRSV HVDFSSSESQ RSRHGSVLSS NFTYHTSDGD ALLLL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.