Details for: CXADR

Gene ID: 1525

Symbol: CXADR

Ensembl ID: ENSG00000154639

Description: CXADR Ig-like cell adhesion molecule

Associated with

Other Information

Genular Protein ID: 3179465320

Symbol: CXAR_HUMAN

Name: Coxsackievirus and adenovirus receptor

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9096397

Title: HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses.

PubMed ID: 9096397

DOI: 10.1073/pnas.94.7.3352

PubMed ID: 9036860

Title: Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5.

PubMed ID: 9036860

DOI: 10.1126/science.275.5304.1320

PubMed ID: 10543405

Title: Genomic organization and chromosomal localization of the human Coxsackievirus B-adenovirus receptor gene.

PubMed ID: 10543405

DOI: 10.1007/s004399900136

PubMed ID: 11573093

Title: Interaction of coxsackievirus B3 with the full length coxsackievirus-adenovirus receptor.

PubMed ID: 11573093

DOI: 10.1038/nsb1001-874

PubMed ID: 14978041

Title: Alternatively spliced soluble coxsackie-adenovirus receptors inhibit coxsackievirus infection.

PubMed ID: 14978041

DOI: 10.1074/jbc.m311754200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10490761

Title: Expression of Coxsackie-adenovirus-receptor and alpha v-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers.

PubMed ID: 10490761

DOI: 10.1038/sj.gt.3301030

PubMed ID: 9733828

Title: The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F.

PubMed ID: 9733828

DOI: 10.1128/jvi.72.10.7909-7915.1998

PubMed ID: 10666333

Title: Expression of the adenovirus receptor and its interaction with the fiber knob.

PubMed ID: 10666333

DOI: 10.1006/excr.1999.4761

PubMed ID: 10814575

Title: The coxsackie-adenovirus receptor (CAR) is used by reference strains and clinical isolates representing all six serotypes of coxsackievirus group B and by swine vesicular disease virus.

PubMed ID: 10814575

DOI: 10.1006/viro.2000.0324

PubMed ID: 11549277

Title: Identification of alternative splice products encoded by the human coxsackie-adenovirus receptor gene.

PubMed ID: 11549277

DOI: 10.1006/bbrc.2001.5535

PubMed ID: 11457744

Title: Human coxsackie-adenovirus receptor is colocalized with integrins alpha(v)beta(3) and alpha(v)beta(5) on the cardiomyocyte sarcolemma and upregulated in dilated cardiomyopathy: implications for cardiotropic viral infections.

PubMed ID: 11457744

DOI: 10.1161/01.cir.104.3.275

PubMed ID: 11316797

Title: Multiple regions within the coxsackievirus and adenovirus receptor cytoplasmic domain are required for basolateral sorting.

PubMed ID: 11316797

DOI: 10.1074/jbc.m009531200

PubMed ID: 11734628

Title: The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction.

PubMed ID: 11734628

DOI: 10.1073/pnas.261452898

PubMed ID: 12297051

Title: Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape.

PubMed ID: 12297051

DOI: 10.1016/s0092-8674(02)00912-1

PubMed ID: 12021372

Title: Fatty acid modification of the coxsackievirus and adenovirus receptor.

PubMed ID: 12021372

DOI: 10.1128/jvi.76.12.6382-6386.2002

PubMed ID: 12468544

Title: The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).

PubMed ID: 12468544

DOI: 10.1074/jbc.m205927200

PubMed ID: 15533241

Title: Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs.

PubMed ID: 15533241

DOI: 10.1186/1471-2121-5-42

PubMed ID: 15364909

Title: The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction.

PubMed ID: 15364909

DOI: 10.1074/jbc.m409061200

PubMed ID: 15304526

Title: A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth.

PubMed ID: 15304526

DOI: 10.1242/jcs.01300

PubMed ID: 15800062

Title: Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial CAR and a JAM-like protein on neutrophils.

PubMed ID: 15800062

DOI: 10.1091/mbc.e05-01-0036

PubMed ID: 19064666

Title: JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation.

PubMed ID: 19064666

DOI: 10.1083/jcb.200805061

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10567268

Title: Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR.

PubMed ID: 10567268

DOI: 10.1126/science.286.5444.1579

PubMed ID: 11080637

Title: Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution.

PubMed ID: 11080637

DOI: 10.1016/s0969-2126(00)00528-1

PubMed ID: 14967025

Title: Solution structure of the coxsackievirus and adenovirus receptor domain 1.

PubMed ID: 14967025

DOI: 10.1021/bi035490x

Sequence Information:

  • Length: 365
  • Mass: 40030
  • Checksum: AB01C6346CB7FE64
  • Sequence:
  • MALLLCFVLL CGVVDFARSL SITTPEEMIE KAKGETAYLP CKFTLSPEDQ GPLDIEWLIS 
    PADNQKVDQV IILYSGDKIY DDYYPDLKGR VHFTSNDLKS GDASINVTNL QLSDIGTYQC 
    KVKKAPGVAN KKIHLVVLVK PSGARCYVDG SEEIGSDFKI KCEPKEGSLP LQYEWQKLSD 
    SQKMPTSWLA EMTSSVISVK NASSEYSGTY SCTVRNRVGS DQCLLRLNVV PPSNKAGLIA 
    GAIIGTLLAL ALIGLIIFCC RKKRREEKYE KEVHHDIRED VPPPKSRTST ARSYIGSNHS 
    SLGSMSPSNM EGYSKTQYNQ VPSEDFERTP QSPTLPPAKV AAPNLSRMGA IPVMIPAQSK 
    DGSIV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.