Details for: CXADR

Gene ID: 1525

Symbol: CXADR

Ensembl ID: ENSG00000154639

Description: CXADR Ig-like cell adhesion molecule

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 381.4325
    Cell Significance Index: -59.3300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 240.0417
    Cell Significance Index: -60.8900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 141.5229
    Cell Significance Index: -58.3000
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 81.2790
    Cell Significance Index: -54.5400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 49.4898
    Cell Significance Index: -47.2500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 48.8501
    Cell Significance Index: -60.2300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 20.9137
    Cell Significance Index: -56.0300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 15.4021
    Cell Significance Index: -60.7800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 5.8731
    Cell Significance Index: 305.0900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.1716
    Cell Significance Index: -9.1300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.8128
    Cell Significance Index: 103.7800
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 3.5302
    Cell Significance Index: 21.7800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 3.5190
    Cell Significance Index: 32.4100
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 3.4134
    Cell Significance Index: 30.3000
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 3.2535
    Cell Significance Index: 7.3400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.8409
    Cell Significance Index: 128.7700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 2.6437
    Cell Significance Index: 186.9700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.6283
    Cell Significance Index: 521.5900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.2631
    Cell Significance Index: 49.0300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.1748
    Cell Significance Index: 392.0400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.1423
    Cell Significance Index: 233.0200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.9380
    Cell Significance Index: 54.1600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.8000
    Cell Significance Index: 221.3300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7422
    Cell Significance Index: 349.4800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.7225
    Cell Significance Index: 49.6300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.5691
    Cell Significance Index: 856.9500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.5522
    Cell Significance Index: 686.2700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.1595
    Cell Significance Index: 71.2700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.1190
    Cell Significance Index: 38.8900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.0542
    Cell Significance Index: 49.1500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.0242
    Cell Significance Index: 17.2500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.9441
    Cell Significance Index: 93.3900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.8129
    Cell Significance Index: 12.1800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.7587
    Cell Significance Index: 272.1300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.7244
    Cell Significance Index: 15.4900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.6313
    Cell Significance Index: 13.8200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5791
    Cell Significance Index: 110.2000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.5507
    Cell Significance Index: 37.0300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4863
    Cell Significance Index: 79.0900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.4677
    Cell Significance Index: 59.9500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.4609
    Cell Significance Index: 59.5500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3903
    Cell Significance Index: 23.4300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3887
    Cell Significance Index: 66.3700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3152
    Cell Significance Index: 17.6900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2740
    Cell Significance Index: 21.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2146
    Cell Significance Index: 7.5400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1865
    Cell Significance Index: 253.5600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1615
    Cell Significance Index: 7.5900
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.1578
    Cell Significance Index: 1.2600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0608
    Cell Significance Index: 38.6100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0285
    Cell Significance Index: 1.0800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0243
    Cell Significance Index: 45.8000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0057
    Cell Significance Index: 8.8000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0109
    Cell Significance Index: -8.2700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0159
    Cell Significance Index: -11.7900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0213
    Cell Significance Index: -0.2900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0347
    Cell Significance Index: -21.6800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0356
    Cell Significance Index: -65.6500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0423
    Cell Significance Index: -31.0400
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0426
    Cell Significance Index: -0.6100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0475
    Cell Significance Index: -6.9000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0489
    Cell Significance Index: -2.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0659
    Cell Significance Index: -37.1900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0679
    Cell Significance Index: -5.0600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0976
    Cell Significance Index: -1.3900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1052
    Cell Significance Index: -2.6300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1215
    Cell Significance Index: -14.1600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1249
    Cell Significance Index: -56.7000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1305
    Cell Significance Index: -27.5000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1535
    Cell Significance Index: -17.5200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1601
    Cell Significance Index: -3.8400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1698
    Cell Significance Index: -17.3400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1779
    Cell Significance Index: -51.1800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1832
    Cell Significance Index: -20.9900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3014
    Cell Significance Index: -6.4200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.3580
    Cell Significance Index: -24.7600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.4094
    Cell Significance Index: -56.2200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4329
    Cell Significance Index: -6.3900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.4868
    Cell Significance Index: -57.4100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5151
    Cell Significance Index: -14.7000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.5173
    Cell Significance Index: -5.3600
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.5341
    Cell Significance Index: -12.3400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5782
    Cell Significance Index: -18.5200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5853
    Cell Significance Index: -60.9400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6157
    Cell Significance Index: -38.8100
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.6652
    Cell Significance Index: -7.5300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6658
    Cell Significance Index: -52.7300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6990
    Cell Significance Index: -36.7000
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.8479
    Cell Significance Index: -12.9000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.8676
    Cell Significance Index: -45.1900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.8831
    Cell Significance Index: -56.9800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8990
    Cell Significance Index: -55.1200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9371
    Cell Significance Index: -29.8500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.0418
    Cell Significance Index: -34.1100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -1.0598
    Cell Significance Index: -26.4700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.1408
    Cell Significance Index: -19.5500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -1.1807
    Cell Significance Index: -8.0000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.2060
    Cell Significance Index: -44.2700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.2170
    Cell Significance Index: -35.8500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -1.2306
    Cell Significance Index: -13.9800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CXADR is a member of the immunoglobulin superfamily, characterized by its unique Ig-like domain structure. This domain is responsible for binding to specific ligands, such as integrins, cadherins, and selectins, facilitating cell-cell interactions and adhesion. CXADR is a transmembrane protein with a short intracellular domain, which allows it to interact with cytoskeletal components and regulate cell shape and movement. The extracellular domain of CXADR contains a PDZ-binding motif, enabling it to interact with other proteins and modulate its activity. **Pathways and Functions** CXADR is involved in various cellular pathways, including: 1. **Cell adhesion and migration**: CXADR interacts with integrins, cadherins, and selectins to regulate cell-cell adhesion, migration, and invasion. 2. **Immune system regulation**: CXADR is expressed on immune cells, such as T cells and dendritic cells, and plays a role in regulating immune responses, including gamma-delta T cell activation and neutrophil chemotaxis. 3. **Cell communication and signaling**: CXADR interacts with other proteins to modulate signaling pathways, including those involved in cardiac muscle cell development and heart development. 4. **Tissue integrity and maintenance**: CXADR is expressed in epithelial cells, where it helps maintain tissue integrity and regulate epithelial structure and function. **Clinical Significance** CXADR has been implicated in various diseases and disorders, including: 1. **Cancer**: CXADR is overexpressed in certain types of cancer, such as prostate cancer, and is associated with tumor progression and metastasis. 2. **Autoimmune diseases**: CXADR is involved in the regulation of immune responses and has been implicated in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 3. **Cardiovascular disease**: CXADR is involved in cardiac muscle cell development and heart development, and its dysregulation has been linked to cardiovascular disease. 4. **Infectious diseases**: CXADR has been identified as a receptor for certain viruses, including Coxsackievirus and adenovirus, and its dysregulation has been linked to infectious diseases. In conclusion, CXADR plays a critical role in maintaining tissue integrity, regulating immune responses, and modulating cellular interactions. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of further research into the functions and clinical significance of CXADR.

Genular Protein ID: 3179465320

Symbol: CXAR_HUMAN

Name: Coxsackievirus and adenovirus receptor

UniProtKB Accession Codes:

P78310 B2R8V8 B7WPI3 D3YHP0 O00694 Q8WWT6 Q8WWT7 Q8WWT8 Q9UKV4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 26 EMDB 8 Ensembl 5 EvolutionaryTrace 1 GO 45 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 23 PDBsum 23 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 7 Pumba 1 RNAct 1 Reactome 2 RefSeq 6 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 UniLectin 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9096397

Title: HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses.

PubMed ID: 9096397

DOI: 10.1073/pnas.94.7.3352

PubMed ID: 9036860

Title: Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5.

PubMed ID: 9036860

DOI: 10.1126/science.275.5304.1320

PubMed ID: 10543405

Title: Genomic organization and chromosomal localization of the human Coxsackievirus B-adenovirus receptor gene.

PubMed ID: 10543405

DOI: 10.1007/s004399900136

PubMed ID: 11573093

Title: Interaction of coxsackievirus B3 with the full length coxsackievirus-adenovirus receptor.

PubMed ID: 11573093

DOI: 10.1038/nsb1001-874

PubMed ID: 14978041

Title: Alternatively spliced soluble coxsackie-adenovirus receptors inhibit coxsackievirus infection.

PubMed ID: 14978041

DOI: 10.1074/jbc.m311754200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10490761

Title: Expression of Coxsackie-adenovirus-receptor and alpha v-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers.

PubMed ID: 10490761

DOI: 10.1038/sj.gt.3301030

PubMed ID: 9733828

Title: The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F.

PubMed ID: 9733828

DOI: 10.1128/jvi.72.10.7909-7915.1998

PubMed ID: 10666333

Title: Expression of the adenovirus receptor and its interaction with the fiber knob.

PubMed ID: 10666333

DOI: 10.1006/excr.1999.4761

PubMed ID: 10814575

Title: The coxsackie-adenovirus receptor (CAR) is used by reference strains and clinical isolates representing all six serotypes of coxsackievirus group B and by swine vesicular disease virus.

PubMed ID: 10814575

DOI: 10.1006/viro.2000.0324

PubMed ID: 11549277

Title: Identification of alternative splice products encoded by the human coxsackie-adenovirus receptor gene.

PubMed ID: 11549277

DOI: 10.1006/bbrc.2001.5535

PubMed ID: 11457744

Title: Human coxsackie-adenovirus receptor is colocalized with integrins alpha(v)beta(3) and alpha(v)beta(5) on the cardiomyocyte sarcolemma and upregulated in dilated cardiomyopathy: implications for cardiotropic viral infections.

PubMed ID: 11457744

DOI: 10.1161/01.cir.104.3.275

PubMed ID: 11316797

Title: Multiple regions within the coxsackievirus and adenovirus receptor cytoplasmic domain are required for basolateral sorting.

PubMed ID: 11316797

DOI: 10.1074/jbc.m009531200

PubMed ID: 11734628

Title: The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction.

PubMed ID: 11734628

DOI: 10.1073/pnas.261452898

PubMed ID: 12297051

Title: Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape.

PubMed ID: 12297051

DOI: 10.1016/s0092-8674(02)00912-1

PubMed ID: 12021372

Title: Fatty acid modification of the coxsackievirus and adenovirus receptor.

PubMed ID: 12021372

DOI: 10.1128/jvi.76.12.6382-6386.2002

PubMed ID: 12468544

Title: The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).

PubMed ID: 12468544

DOI: 10.1074/jbc.m205927200

PubMed ID: 15533241

Title: Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs.

PubMed ID: 15533241

DOI: 10.1186/1471-2121-5-42

PubMed ID: 15364909

Title: The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction.

PubMed ID: 15364909

DOI: 10.1074/jbc.m409061200

PubMed ID: 15304526

Title: A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth.

PubMed ID: 15304526

DOI: 10.1242/jcs.01300

PubMed ID: 15800062

Title: Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial CAR and a JAM-like protein on neutrophils.

PubMed ID: 15800062

DOI: 10.1091/mbc.e05-01-0036

PubMed ID: 19064666

Title: JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation.

PubMed ID: 19064666

DOI: 10.1083/jcb.200805061

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10567268

Title: Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR.

PubMed ID: 10567268

DOI: 10.1126/science.286.5444.1579

PubMed ID: 11080637

Title: Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution.

PubMed ID: 11080637

DOI: 10.1016/s0969-2126(00)00528-1

PubMed ID: 14967025

Title: Solution structure of the coxsackievirus and adenovirus receptor domain 1.

PubMed ID: 14967025

DOI: 10.1021/bi035490x

Sequence Information:

  • Length: 365
  • Mass: 40030
  • Checksum: AB01C6346CB7FE64
  • Sequence:
    • MALLLCFVLL CGVVDFARSL SITTPEEMIE KAKGETAYLP CKFTLSPEDQ GPLDIEWLIS 
PADNQKVDQV IILYSGDKIY DDYYPDLKGR VHFTSNDLKS GDASINVTNL QLSDIGTYQC 
KVKKAPGVAN KKIHLVVLVK PSGARCYVDG SEEIGSDFKI KCEPKEGSLP LQYEWQKLSD 
SQKMPTSWLA EMTSSVISVK NASSEYSGTY SCTVRNRVGS DQCLLRLNVV PPSNKAGLIA 
GAIIGTLLAL ALIGLIIFCC RKKRREEKYE KEVHHDIRED VPPPKSRTST ARSYIGSNHS 
SLGSMSPSNM EGYSKTQYNQ VPSEDFERTP QSPTLPPAKV AAPNLSRMGA IPVMIPAQSK 
DGSIV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.