Details for: Hipk2
Associated with
Other Information
Genular Protein ID: 3586361893
Symbol: HIPK2_MOUSE
Name: Homeodomain-interacting protein kinase 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9748262
Title: Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors.
PubMed ID: 9748262
PubMed ID: 11078605
Title: Identification and cloning of a CD43-associated serine/threonine kinase.
PubMed ID: 11078605
PubMed ID: 11267674
Title: Isolation and characterization of cDNAs for the protein kinase HIPK2.
PubMed ID: 11267674
PubMed ID: 14990717
Title: US11 of herpes simplex virus type 1 interacts with HIPK2 and antagonizes HIPK2-induced cell growth arrest.
PubMed ID: 14990717
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 10535925
Title: Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1.
PubMed ID: 10535925
PubMed ID: 11593421
Title: High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth.
PubMed ID: 11593421
PubMed ID: 11798164
Title: The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues.
PubMed ID: 11798164
PubMed ID: 11780126
Title: Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.
PubMed ID: 11780126
DOI: 10.1038/ncb714
PubMed ID: 14567915
Title: Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.
PubMed ID: 14567915
PubMed ID: 15526030
Title: Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation.
PubMed ID: 15526030
PubMed ID: 15082531
Title: Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK.
PubMed ID: 15082531
DOI: 10.1101/gad.1170604
PubMed ID: 15492043
Title: Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival.
PubMed ID: 15492043
PubMed ID: 16917507
Title: Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation.
PubMed ID: 16917507
PubMed ID: 19714248
Title: Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha.
PubMed ID: 19714248
PubMed ID: 20307497
Title: Homeodomain-interacting protein kinase 2 (HIPK2) targets beta-catenin for phosphorylation and proteasomal degradation.
PubMed ID: 20307497
PubMed ID: 20637728
Title: Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization.
PubMed ID: 20637728
PubMed ID: 20231426
Title: Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation.
PubMed ID: 20231426
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 20579985
Title: Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis.
PubMed ID: 20579985
PubMed ID: 23485397
Title: HIPK2 catalytic activity and subcellular localization are regulated by activation-loop Y354 autophosphorylation.
PubMed ID: 23485397
Sequence Information:
- Length: 1196
- Mass: 130498
- Checksum: 5C863BE377F3AAEF
- Sequence:
MAPVYEGMAS HVQVFSPHTL QSSAFCSVKK LKVEPSSNWD MTGYGSHSKV YSQSKNIPPS QPASTTVSTS LPIPNPSLPY EQTIIFPGST GHIVVTSASS TSVTGQVLGG PHNLMRRSTV SLLDTYQKCG LKRKSEEIEN TSSVQIIEEH PPMIQNNASG ATVATATTST ATSKNSGSNS EGDYQLVQHE VLCSMTNTYE VLEFLGRGTF GQVVKCWKRG TNEIVAIKIL KNHPSYARQG QIEVSILARL STESADDYNF VRAYECFQHK NHTCLVFEML EQNLYDFLKQ NKFSPLPLKY IRPVLQQVAT ALMKLKSLGL IHADLKPENI MLVDPSRQPY RVKVIDFGSA SHVSKAVCST YLQSRYYRAP EIILGLPFCE AIDMWSLGCV IAELFLGWPL YPGASEYDQI RYISQTQGLP AEYLLSAGTK TTRFFNRDTD SPYPLWRLKT PDDHEAETGI KSKEARKYIF NCLDDMAQVN MTTDLEGSDM LVEKADRREF IDLLKKMLTI DADKRVTPIE TLNHPFVTMT HLLDFPHSAH VKSCFQNMEI CKRRVNMYDT VNQSKTPFIT HVAPSTSTNL TMTFNNQLTT VHNQAPTTSS ATLSLANPEV SILNYQSALY QPSAASMAAV APRSMPLQTG TAQICARPDP FQQALIVCPP GFQGLQASPS KHAGYSVRME NAVPIVTQAP GAQPLQIQPG LLAQQAWPGG AQQILLPPAW QQLTGVATHT SVQHAAVIPE TMAGTQQLAD WRNTHAHGSH YNPIMQQPAL LTGHVTLPAA QPLNVGVAHV MRQQPTSTTS SRKSKQHQSS VRNVSTCEVT SSQAISSPQR SKRVKENTPP RCAMVHSSPA CSTSVTCGWG DVASSTTRER QRQTIVIPDT PSPTVSVITI SSDTDEEEEQ KHAPTSTVSK QRKNVISCVT VHDSPYSDSS SNTSPYSVQQ RTGHNGTNTL DTKGGLENHC TGNPRTIIVP PLKTQASEVL VECDSLGPAI SASHHSSSFK SKSSSTVTST SGHSSGSSSG AIAYRQQRPG PHFQQQQPLN LSQAQQHMAA DRTGSHRRQQ AYITPTMAQA PYTFPHNSPS HGTVHPHLAA AAHLPTQPHL YTYTAPTALG STGTVAHLVA SQGSARHTVQ HTAYPASIVH QVPVSMGPRV LPSPTIHPSQ YPAQFAHQTY ISASPASTVY TGYPLSPAKV NQYPYI
Genular Protein ID: 1511139624
Symbol: Q5D0E9_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 1169
- Mass: 127676
- Checksum: F8C5ED0ADE4CFE4F
- Sequence:
MAPVYEGMAS HVQVFSPHTL QSSAFCSVKK LKVEPSSNWD MTGYGSHSKV YSQSKNIPPS QPASTTVSTS LPIPNPSLPY EQTIIFPGST GHIVVTSASS TSVTGQVLGG PHNLMRRSTV SLLDTYQKCG LKRKSEEIEN TSSVQIIEEH PPMIQNNASG ATVATATTST ATSKNSGSNS EGDYQLVQHE VLCSMTNTYE VLEFLGRGTF GQVVKCWKRG TNEIVAIKIL KNHPSYARQG QIEVSILARL STESADDYNF VRAYECFQHK NHTCLVFEML EQNLYDFLKQ NKFSPLPLKY IRPVLQQVAT ALMKLKSLGL IHADLKPENI MLVDPSRQPY RVKVIDFGSA SHVSKAVCST YLQSRYYRAP EIILGLPFCE AIDMWSLGCV IAELFLGWPL YPGASEYDQI RYISQTQGLP AEYLLSAGTK TTRFFNRDTD SPYPLWRLKT PDDHEAETGI KSKEARKYIF NCLDDMAQVN MTTDLEGSDM LVEKADRREF IDLLKKMLTI DADKRVTPIE TLNHPFVTMT HLLDFPHSAH VKSCFQNMEI CKRRVNMYDT VNQSKTPFIT HVAPSTSTNL TMTFNNQLTT VHNQPSAASM AAVAPRSMPL QTGTAQICAR PDPFQQALIV CPPGFQGLQA SPSKHAGYSV RMENAVPIVT QAPGAQPLQI QPGLLAQQAW PGGAQQILLP PAWQQLTGVA THTSVQHAAV IPETMAGTQQ LADWRNTHAH GSHYNPIMQQ PALLTGHVTL PAAQPLNVGV AHVMRQQPTS TTSSRKSKQH QSSVRNVSTC EVTSSQAISS PQRSKRVKEN TPPRCAMVHS SPACSTSVTC GWGDVASSTT RERQRQTIVI PDTPSPTVSV ITISSDTDEE EEQKHAPTST VSKQRKNVIS CVTVHDSPYS DSSSNTSPYS VQQRTGHNGT NTLDTKGGLE NHCTGNPRTI IVPPLKTQAS EVLVECDSLG PAISASHHSS SFKSKSSSTV TSTSGHSSGS SSGAIAYRQQ RPGPHFQQQQ PLNLSQAQQH MAADRTGSHR RQQAYITPTM AQAPYTFPHN SPSHGTVHPH LAAAAHLPTQ PHLYTYTAPT ALGSTGTVAH LVASQGSARH TVQHTAYPAS IVHQVPVSMG PRVLPSPTIH PSQYPAQFAH QTYISASPAS TVYTGYPLSP AKVNQYPYI
Genular Protein ID: 2725113854
Symbol: A0A0R4J202_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 1168
- Mass: 127548
- Checksum: CE0A3C90208E3633
- Sequence:
MAPVYEGMAS HVQVFSPHTL QSSAFCSVKK LKVEPSSNWD MTGYGSHSKV YSQSKNIPPS QPASTTVSTS LPIPNPSLPY EQTIIFPGST GHIVVTSASS TSVTGQVLGG PHNLMRRSTV SLLDTYQKCG LKRKSEEIEN TSSVQIIEEH PPMIQNNASG ATVATATTST ATSKNSGSNS EGDYQLVQHE VLCSMTNTYE VLEFLGRGTF GQVVKCWKRG TNEIVAIKIL KNHPSYARQG QIEVSILARL STESADDYNF VRAYECFQHK NHTCLVFEML EQNLYDFLKQ NKFSPLPLKY IRPVLQQVAT ALMKLKSLGL IHADLKPENI MLVDPSRQPY RVKVIDFGSA SHVSKAVCST YLQSRYYRAP EIILGLPFCE AIDMWSLGCV IAELFLGWPL YPGASEYDQI RYISQTQGLP AEYLLSAGTK TTRFFNRDTD SPYPLWRLKT PDDHEAETGI KSKEARKYIF NCLDDMAQVN MTTDLEGSDM LVEKADRREF IDLLKKMLTI DADKRVTPIE TLNHPFVTMT HLLDFPHSAH VKSCFQNMEI CKRRVNMYDT VNQSKTPFIT HVAPSTSTNL TMTFNNQLTT VHNQPSAASM AAVAPRSMPL QTGTAQICAR PDPFQQALIV CPPGFQGLQA SPSKHAGYSV RMENAVPIVT QAPGAQPLQI QPGLLAQAWP GGAQQILLPP AWQQLTGVAT HTSVQHAAVI PETMAGTQQL ADWRNTHAHG SHYNPIMQQP ALLTGHVTLP AAQPLNVGVA HVMRQQPTST TSSRKSKQHQ SSVRNVSTCE VTSSQAISSP QRSKRVKENT PPRCAMVHSS PACSTSVTCG WGDVASSTTR ERQRQTIVIP DTPSPTVSVI TISSDTDEEE EQKHAPTSTV SKQRKNVISC VTVHDSPYSD SSSNTSPYSV QQRTGHNGTN TLDTKGGLEN HCTGNPRTII VPPLKTQASE VLVECDSLGP AISASHHSSS FKSKSSSTVT STSGHSSGSS SGAIAYRQQR PGPHFQQQQP LNLSQAQQHM AADRTGSHRR QQAYITPTMA QAPYTFPHNS PSHGTVHPHL AAAAHLPTQP HLYTYTAPTA LGSTGTVAHL VASQGSARHT VQHTAYPASI VHQVPVSMGP RVLPSPTIHP SQYPAQFAHQ TYISASPAST VYTGYPLSPA KVNQYPYI
Genular Protein ID: 95022504
Symbol: A0A0R4J204_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 1161
- Mass: 126800
- Checksum: 9311C7949B2D98D9
- Sequence:
MASHVQVFSP HTLQSSAFCS VKKLKVEPSS NWDMTGYGSH SKVYSQSKNI PPSQPASTTV STSLPIPNPS LPYEQTIIFP GSTGHIVVTS ASSTSVTGQV LGGPHNLMRR STVSLLDTYQ KCGLKRKSEE IENTSSVQII EEHPPMIQNN ASGATVATAT TSTATSKNSG SNSEGDYQLV QHEVLCSMTN TYEVLEFLGR GTFGQVVKCW KRGTNEIVAI KILKNHPSYA RQGQIEVSIL ARLSTESADD YNFVRAYECF QHKNHTCLVF EMLEQNLYDF LKQNKFSPLP LKYIRPVLQQ VATALMKLKS LGLIHADLKP ENIMLVDPSR QPYRVKVIDF GSASHVSKAV CSTYLQSRYY RAPEIILGLP FCEAIDMWSL GCVIAELFLG WPLYPGASEY DQIRYISQTQ GLPAEYLLSA GTKTTRFFNR DTDSPYPLWR LKTPDDHEAE TGIKSKEARK YIFNCLDDMA QVNMTTDLEG SDMLVEKADR REFIDLLKKM LTIDADKRVT PIETLNHPFV TMTHLLDFPH SAHVKSCFQN MEICKRRVNM YDTVNQSKTP FITHVAPSTS TNLTMTFNNQ LTTVHNQPSA ASMAAVAPRS MPLQTGTAQI CARPDPFQQA LIVCPPGFQG LQASPSKHAG YSVRMENAVP IVTQAPGAQP LQIQPGLLAQ AWPGGAQQIL LPPAWQQLTG VATHTSVQHA AVIPETMAGT QQLADWRNTH AHGSHYNPIM QQPALLTGHV TLPAAQPLNV GVAHVMRQQP TSTTSSRKSK QHQSSVRNVS TCEVTSSQAI SSPQRSKRVK ENTPPRCAMV HSSPACSTSV TCGWGDVASS TTRERQRQTI VIPDTPSPTV SVITISSDTD EEEEQKHAPT STVSKQRKNV ISCVTVHDSP YSDSSSNTSP YSVQQRTGHN GTNTLDTKGG LENHCTGNPR TIIVPPLKTQ ASEVLVECDS LGPAISASHH SSSFKSKSSS TVTSTSGHSS GSSSGAIAYR QQRPGPHFQQ QQPLNLSQAQ QHMAADRTGS HRRQQAYITP TMAQAPYTFP HNSPSHGTVH PHLAAAAHLP TQPHLYTYTA PTALGSTGTV AHLVASQGSA RHTVQHTAYP ASIVHQVPVS MGPRVLPSPT IHPSQYPAQF AHQTYISASP ASTVYTGYPL SPAKVNQYPY I
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.