Genular: Defining Cellular Identity and Function

Details for: H2ac18

Gene ID: 15267

Symbol: H2ac18

Ensembl ID: ENSMUSG00000064220

Description: H2A clustered histone 18

Associated with

Base-excision repair, ap site formation
(R-MMU-73929)
Base excision repair
(R-MMU-73884)
Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular senescence
(R-MMU-2559583)
Chromatin modifying enzymes
(R-MMU-3247509)
Chromatin organization
(R-MMU-4839726)
Chromosome maintenance
(R-MMU-73886)
Cleavage of the damaged purine
(R-MMU-110331)
Condensation of prophase chromosomes
(R-MMU-2299718)
Deposition of new cenpa-containing nucleosomes at the centromere
(R-MMU-606279)
Depurination
(R-MMU-73927)
Deubiquitination
(R-MMU-5688426)
Dna damage/telomere stress induced senescence
(R-MMU-2559586)
Dna repair
(R-MMU-73894)
Epigenetic regulation of gene expression
(R-MMU-212165)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Hdacs deacetylate histones
(R-MMU-3214815)
Inhibition of dna recombination at telomere
(R-MMU-9670095)
Metabolism of proteins
(R-MMU-392499)
Metalloprotease dubs
(R-MMU-5689901)
Mitotic prophase
(R-MMU-68875)
M phase
(R-MMU-68886)
Nucleosome assembly
(R-MMU-774815)
Post-translational protein modification
(R-MMU-597592)
Prc2 methylates histones and dna
(R-MMU-212300)
Recognition and association of dna glycosylase with site containing an affected purine
(R-MMU-110330)
Rmts methylate histone arginines
(R-MMU-3214858)
Rna polymerase ii transcription
(R-MMU-73857)
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function
(R-MMU-8936459)
Telomere maintenance
(R-MMU-157579)
Transcriptional regulation by runx1
(R-MMU-8878171)
Ub-specific processing proteases
(R-MMU-5689880)
Uch proteinases
(R-MMU-5689603)
Nucleus
(GO:0005634)

Other Information

Proteins

Histone H2A type 2-A

Genular Protein ID: 3820029971

Symbol: H2A2A_MOUSE

Name: Histone H2A type 2-A

UniProtKB Accession Codes:

Q6GSS7 P20670 Q811M3

Database IDs:

Citations:

PubMed ID: 2587235

Title: The mouse histone H2a.2 gene from chromosome 3.

PubMed ID: 2587235

DOI: 10.1093/nar/17.21.8876

PubMed ID: 8858345

Title: Characterization of the 55-kb mouse histone gene cluster on chromosome 3.

PubMed ID: 8858345

DOI: 10.1101/gr.6.8.702

PubMed ID: 12408966

Title: The human and mouse replication-dependent histone genes.

PubMed ID: 12408966

DOI: 10.1016/s0888-7543(02)96850-3

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7217105

Title: Quantitative determination of histone modification. H2A acetylation and phosphorylation.

PubMed ID: 7217105

DOI: 10.1016/s0021-9258(19)69487-1

PubMed ID: 15525528

Title: Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.

PubMed ID: 15525528

DOI: 10.1016/j.devcel.2004.10.005

PubMed ID: 15509584

Title: Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation.

PubMed ID: 15509584

DOI: 10.1074/jbc.c400493200

PubMed ID: 16699504

Title: Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells.

PubMed ID: 16699504

DOI: 10.1038/ncb1413

PubMed ID: 21925322

Title: Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification.

PubMed ID: 21925322

DOI: 10.1016/j.cell.2011.08.008

PubMed ID: 24681537

Title: Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark.

PubMed ID: 24681537

DOI: 10.1038/nchembio.1497

PubMed ID: 24352239

Title: Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification.

PubMed ID: 24352239

DOI: 10.1038/nature12819

PubMed ID: 27105115

Title: Metabolic regulation of gene expression by histone lysine beta-hydroxybutyrylation.

PubMed ID: 27105115

DOI: 10.1016/j.molcel.2016.03.036

Sequence Information:

Length: 130
Mass: 14095
Checksum: 53AEDC6CE3FE8317
Sequence:

MSGRGKQGGK ARAKAKSRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YMAAVLEYLT 
AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK 
TESHHKAKGK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: H2ac18

Associated with

Other Information

The mouse histone H2a.2 gene from chromosome 3. PubMed ID: 2587235

Characterization of the 55-kb mouse histone gene cluster on chromosome 3. PubMed ID: 8858345

The human and mouse replication-dependent histone genes. PubMed ID: 12408966

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Quantitative determination of histone modification. H2A acetylation and phosphorylation. PubMed ID: 7217105

Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. PubMed ID: 15525528

Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation. PubMed ID: 15509584

Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. PubMed ID: 16699504

Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. PubMed ID: 21925322

Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark. PubMed ID: 24681537

Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification. PubMed ID: 24352239

Metabolic regulation of gene expression by histone lysine beta-hydroxybutyrylation. PubMed ID: 27105115