Details for: TEX28

Gene ID: 1527

Symbol: TEX28

Ensembl ID: ENSG00000278057

Description: testis expressed 28

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: plasma cell (CL0000786)
    Fold Change: 1.94
    Marker Score: 2172
  • Cell Name: B cell (CL0000236)
    Fold Change: 1.27
    Marker Score: 1211
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.16
    Marker Score: 7693
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30408
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2413
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5355
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.92
    Marker Score: 2743
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.91
    Marker Score: 1475
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5292
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.86
    Marker Score: 498
  • Cell Name: T cell (CL0000084)
    Fold Change: 0.83
    Marker Score: 1425
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 713
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.66
    Marker Score: 530
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.63
    Marker Score: 613
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.48
    Marker Score: 762
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.21
    Marker Score: 95
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.2
    Marker Score: 177
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.19
    Marker Score: 395
  • Cell Name: pericyte (CL0000669)
    Fold Change: 0.09
    Marker Score: 55
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.08
    Marker Score: 152
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: 0.08
    Marker Score: 59
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.07
    Marker Score: 80.5
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.07
    Marker Score: 17
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.06
    Marker Score: 22
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 0.06
    Marker Score: 17
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.06
    Marker Score: 35
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.05
    Marker Score: 17
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.05
    Marker Score: 17
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.05
    Marker Score: 13
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.05
    Marker Score: 14
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.05
    Marker Score: 16
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.05
    Marker Score: 707
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.04
    Marker Score: 15
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.04
    Marker Score: 13
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 0.04
    Marker Score: 49
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.04
    Marker Score: 18
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.04
    Marker Score: 14
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.04
    Marker Score: 493
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: 0.04
    Marker Score: 17
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.04
    Marker Score: 16
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 0.03
    Marker Score: 18
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.03
    Marker Score: 35
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 0.03
    Marker Score: 66
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.03
    Marker Score: 14
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.03
    Marker Score: 11
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 0.03
    Marker Score: 44
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.03
    Marker Score: 17
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: 0.03
    Marker Score: 46
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.03
    Marker Score: 14
  • Cell Name: leukocyte (CL0000738)
    Fold Change: 0.03
    Marker Score: 16
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.03
    Marker Score: 19
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.03
    Marker Score: 10
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.03
    Marker Score: 16
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.03
    Marker Score: 11
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 0.02
    Marker Score: 21
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.02
    Marker Score: 17
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.02
    Marker Score: 12
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.02
    Marker Score: 15
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.02
    Marker Score: 16
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.02
    Marker Score: 129
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 0.02
    Marker Score: 14
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 0.02
    Marker Score: 13
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 0.02
    Marker Score: 11
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 0.02
    Marker Score: 15
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.02
    Marker Score: 10
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.02
    Marker Score: 13
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 0.02
    Marker Score: 17
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: 0.02
    Marker Score: 13
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.02
    Marker Score: 12
  • Cell Name: Unknown (CL0000003)
    Fold Change: 0.02
    Marker Score: 59
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.02
    Marker Score: 10
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.02
    Marker Score: 9
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.02
    Marker Score: 13
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.02
    Marker Score: 14
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.02
    Marker Score: 64
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 0.02
    Marker Score: 17
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.02
    Marker Score: 19
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: 0.02
    Marker Score: 15
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.02
    Marker Score: 16
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.02
    Marker Score: 45
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 0.02
    Marker Score: 17
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.02
    Marker Score: 10
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 0.01
    Marker Score: 16
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.01
    Marker Score: 35
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 0.01
    Marker Score: 15
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.01
    Marker Score: 32
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 0.01
    Marker Score: 16
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.01
    Marker Score: 54
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.01
    Marker Score: 14
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 0.01
    Marker Score: 13
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.01
    Marker Score: 13.5
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.01
    Marker Score: 17
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.01
    Marker Score: 11
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.01
    Marker Score: 44
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.01
    Marker Score: 12
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.01
    Marker Score: 12
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.01
    Marker Score: 13
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 0.01
    Marker Score: 16
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.01
    Marker Score: 21
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.01
    Marker Score: 16

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Other Information

**Key characteristics:** * TEX28 is a transmembrane protein with a molecular weight of approximately 130 kDa. * It is expressed in high levels in the testes of mammals. * It is involved in the regulation of the immune system. * It has been shown to play a role in the development of cancer. **Pathways and functions:** * TEX28 is involved in the regulation of the immune system. * It is expressed in high levels in the testes of mammals, which are sites of the immune system. * TEX28 is a key regulator of the activation of T cells. * It interacts with the CD28 protein, which is expressed on the surface of T cells. * This interaction helps to activate T cells and promote the development of an immune response. * TEX28 also interacts with the CD80 and CD86 proteins, which are expressed on the surface of antigen-presenting cells. * This interaction helps to activate CD8+ T cells and promote the development of an immune response against foreign pathogens. **Clinical significance:** * TEX28 is a potential target for cancer immunotherapy. * Studies have shown that blocking TEX28 signaling can inhibit the growth of cancer cells in vitro and in vivo. * TEX28 inhibitors are being investigated as a treatment for cancer. **Conclusion:** TEX28 is a critical protein for the regulation of the immune system. Its overexpression is associated with the development of cancer, and it is a potential target for cancer immunotherapy.

Genular Protein ID: 305226738

Symbol: TEX28_HUMAN

Name: Testis-specific protein TEX28

UniProtKB Accession Codes:

O15482 B1B1E8 D3DWW5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 8 EPD 1 Ensembl 3 GO 2 GeneCards 3 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 3 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 2 SAM 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9268643

Title: Identification of a gene within the tandem array of red and green color pigment genes.

PubMed ID: 9268643

DOI: 10.1006/geno.1997.4830

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 410
  • Mass: 46131
  • Checksum: 8E455A761D52A660
  • Sequence:
    • MVLKAEHTRS PSATLPSNVP SCRSLSSSED GPSGPSSLAD GGLAHNLQDS VRHRILYLSE 
QLRVEKASRD GNTVSYLKLV SKADRHQVPH IQQAFEKVNQ RASATIAQIE HRLHQCHQQL 
QELEEGCRPE GLLLMAESDP ANCEPPSEKA LLSEPPEPGG EDGPVNLPHA SRPFILESRF 
QSLQQGTCLE TEDVAQQQNL LLQKVKAELE EAKRFHISLQ ESYHSLKERS LTDLQLLLES 
LQEEKCRQAL MEEQVNGRLQ GQLNEIYNLK HNLACSEERM AYLSYERAKE IWEITETFKS 
RISKLEMLQQ VTQLEAAEHL QSRPPQMLFK FLSPRLSLAT VLLVFVSTLC ACPSSLISSR 
LCTCTMLMLI GLGVLAWQRW RAIPATDWQE WVPSRCRLYS KDSGPPADGP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.