CYB5A | ENSG00000166347 | NCBI 1528

Details for: CYB5A

Gene ID: 1528

Symbol: CYB5A

Ensembl ID: ENSG00000166347

Description: cytochrome b5 type A

Associated with

Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
(R-HSA-9609523)
Metabolism
(R-HSA-1430728)
Metabolism of vitamins and cofactors
(R-HSA-196854)
Metabolism of water-soluble vitamins and cofactors
(R-HSA-196849)
Protein localization
(R-HSA-9609507)
Vitamin c (ascorbate) metabolism
(R-HSA-196836)
Cytochrome-c oxidase activity
(GO:0004129)
Cytosol
(GO:0005829)
Electron transport chain
(GO:0022900)
Endoplasmic reticulum membrane
(GO:0005789)
Enzyme binding
(GO:0019899)
Heme binding
(GO:0020037)
Intracellular membrane-bounded organelle
(GO:0043231)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Mitochondrial outer membrane
(GO:0005741)
Protein binding
(GO:0005515)
Proton transmembrane transport
(GO:1902600)

Other Information

Proteins

Cytochrome b5

Genular Protein ID: 3707054017

Symbol: CYB5_HUMAN

Name: Cytochrome b5

UniProtKB Accession Codes:

P00167 A8MV91 F8WEU4 Q6IB14

Database IDs:

Citations:

PubMed ID: 3178851

Title: The complete nucleotide sequence of human liver cytochrome b5 mRNA.

PubMed ID: 3178851

DOI: 10.1016/s0006-291x(88)80881-7

PubMed ID: 1712589

Title: The human liver and reticulocyte cytochrome b5 mRNAs are products from a single gene.

PubMed ID: 1712589

DOI: 10.1016/0006-291x(91)91776-9

PubMed ID: 7733981

Title: The isolation and characterization of the human cytochrome b5 gene.

PubMed ID: 7733981

DOI: 10.1006/bbrc.1995.1582

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 4030743

Title: Amino acid sequences of cytochrome b5 from human, porcine, and bovine erythrocytes and comparison with liver microsomal cytochrome b5.

PubMed ID: 4030743

DOI: 10.1093/oxfordjournals.jbchem.a135224

PubMed ID: 4993957

Title: Amino acid sequences of tryptic peptides of cytochromes b5 from microsomes of human, monkey, porcine, and chicken liver.

PubMed ID: 4993957

DOI: 10.1016/s0021-9258(18)62368-3

PubMed ID: 5062820

Title: Cytochrome b5 from a normal human liver. Isolation and the partial amino acid sequence.

PubMed ID: 5062820

DOI: 10.1016/s0021-9258(19)45520-8

PubMed ID: 4770377

Title: Structural studies of cytochrome b5. 3. Sequential studies on human liver cytochrome b5.

PubMed ID: 4770377

PubMed ID: 2752049

Title: Structure of cytochrome b5 and its topology in the microsomal membrane.

PubMed ID: 2752049

DOI: 10.1016/0167-4838(89)90143-x

PubMed ID: 8168836

Title: A splicing mutation in the cytochrome b5 gene from a patient with congenital methemoglobinemia and pseudohermaphrodism.

PubMed ID: 8168836

DOI: 10.1007/bf00202825

PubMed ID: 20080843

Title: Isolated 17,20-lyase deficiency due to the cytochrome b5 mutation W27X.

PubMed ID: 20080843

DOI: 10.1210/jc.2008-1745

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 22170710

Title: A missense mutation in the human cytochrome B5 gene causes 46,XY disorder of sex development due to true isolated 17,20 lyase deficiency.

PubMed ID: 22170710

DOI: 10.1210/jc.2011-2413

Sequence Information:

Length: 134
Mass: 15330
Checksum: B6AD2AB747555048
Sequence:

MAEQSDEAVK YYTLEEIQKH NHSKSTWLIL HHKVYDLTKF LEEHPGGEEV LREQAGGDAT 
ENFEDVGHST DAREMSKTFI IGELHPDDRP KLNKPPETLI TTIDSSSSWW TNWVIPAISA 
VAVALMYRLY MAED

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CYB5A

Associated with

Other Information

The complete nucleotide sequence of human liver cytochrome b5 mRNA. PubMed ID: 3178851

The human liver and reticulocyte cytochrome b5 mRNAs are products from a single gene. PubMed ID: 1712589

The isolation and characterization of the human cytochrome b5 gene. PubMed ID: 7733981

DNA sequence and analysis of human chromosome 18. PubMed ID: 16177791

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Amino acid sequences of cytochrome b5 from human, porcine, and bovine erythrocytes and comparison with liver microsomal cytochrome b5. PubMed ID: 4030743

Amino acid sequences of tryptic peptides of cytochromes b5 from microsomes of human, monkey, porcine, and chicken liver. PubMed ID: 4993957

Cytochrome b5 from a normal human liver. Isolation and the partial amino acid sequence. PubMed ID: 5062820

Structural studies of cytochrome b5. 3. Sequential studies on human liver cytochrome b5. PubMed ID: 4770377

Structure of cytochrome b5 and its topology in the microsomal membrane. PubMed ID: 2752049

A splicing mutation in the cytochrome b5 gene from a patient with congenital methemoglobinemia and pseudohermaphrodism. PubMed ID: 8168836

Isolated 17,20-lyase deficiency due to the cytochrome b5 mutation W27X. PubMed ID: 20080843

Initial characterization of the human central proteome. PubMed ID: 21269460

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

A missense mutation in the human cytochrome B5 gene causes 46,XY disorder of sex development due to true isolated 17,20 lyase deficiency. PubMed ID: 22170710