Details for: CYB561
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 133.3374
Cell Significance Index: -20.7400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 74.5141
Cell Significance Index: -18.9000 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 30.9900
Cell Significance Index: -20.8000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 17.8268
Cell Significance Index: -17.0200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 16.8295
Cell Significance Index: -20.7500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 8.0482
Cell Significance Index: -21.5600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 5.2686
Cell Significance Index: -20.7900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 3.3130
Cell Significance Index: 327.7300 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 1.7001
Cell Significance Index: 28.0200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.6517
Cell Significance Index: 77.0100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.4212
Cell Significance Index: 1283.2500 - Cell Name: peg cell (CL4033014)
Fold Change: 1.4119
Cell Significance Index: 32.6200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.2011
Cell Significance Index: 130.6500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.9860
Cell Significance Index: 51.2200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.8812
Cell Significance Index: 23.9900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.8747
Cell Significance Index: 8.0600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7718
Cell Significance Index: 154.8200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.6130
Cell Significance Index: 110.5100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.5793
Cell Significance Index: 316.3900 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.5149
Cell Significance Index: 8.2600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.4733
Cell Significance Index: 327.3500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4596
Cell Significance Index: 31.7900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.4548
Cell Significance Index: 55.9300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.4519
Cell Significance Index: 33.6800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.4410
Cell Significance Index: 75.3100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4046
Cell Significance Index: 18.3400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4020
Cell Significance Index: 8.7100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.3940
Cell Significance Index: 50.5100 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.3622
Cell Significance Index: 46.8000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.3350
Cell Significance Index: 15.7500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3349
Cell Significance Index: 9.6500 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.3208
Cell Significance Index: 3.3200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3081
Cell Significance Index: 8.6100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.2921
Cell Significance Index: 20.6600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2887
Cell Significance Index: 54.9500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2664
Cell Significance Index: 43.3400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2655
Cell Significance Index: 95.2400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2541
Cell Significance Index: 112.3500 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.2271
Cell Significance Index: 2.5800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.1681
Cell Significance Index: 19.1900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1397
Cell Significance Index: 8.8100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0939
Cell Significance Index: 2.0000 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 0.0665
Cell Significance Index: 1.0100 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.0575
Cell Significance Index: 1.2600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0441
Cell Significance Index: 8.7600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0415
Cell Significance Index: 1.4600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0240
Cell Significance Index: 18.1700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0116
Cell Significance Index: 0.2900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0009
Cell Significance Index: -0.0400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0022
Cell Significance Index: -0.0600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0043
Cell Significance Index: -8.1300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0044
Cell Significance Index: -3.2000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0054
Cell Significance Index: -3.9800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0080
Cell Significance Index: -12.2600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0086
Cell Significance Index: -15.7900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0090
Cell Significance Index: -1.2300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0112
Cell Significance Index: -6.9800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0118
Cell Significance Index: -7.4800 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.0161
Cell Significance Index: -0.1100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0197
Cell Significance Index: -26.7900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0206
Cell Significance Index: -11.5900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0295
Cell Significance Index: -0.9500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0359
Cell Significance Index: -1.3600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0419
Cell Significance Index: -8.8300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0451
Cell Significance Index: -20.4700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0548
Cell Significance Index: -15.7600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0585
Cell Significance Index: -6.7000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0641
Cell Significance Index: -7.4700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0671
Cell Significance Index: -6.8500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1139
Cell Significance Index: -16.5500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1143
Cell Significance Index: -1.5600 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.1157
Cell Significance Index: -1.7900 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1480
Cell Significance Index: -3.7800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1491
Cell Significance Index: -10.0300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1558
Cell Significance Index: -4.4500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1634
Cell Significance Index: -3.1900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1794
Cell Significance Index: -21.1600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1987
Cell Significance Index: -20.6900 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.2055
Cell Significance Index: -2.4500 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.2102
Cell Significance Index: -3.1500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2164
Cell Significance Index: -13.9600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2259
Cell Significance Index: -17.8900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2273
Cell Significance Index: -13.9700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2318
Cell Significance Index: -17.7900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2400
Cell Significance Index: -12.6000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2515
Cell Significance Index: -15.4200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2777
Cell Significance Index: -14.0400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2851
Cell Significance Index: -14.8500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.3144
Cell Significance Index: -9.2400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3315
Cell Significance Index: -18.6000 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3405
Cell Significance Index: -12.5000 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.3449
Cell Significance Index: -4.9100 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3572
Cell Significance Index: -10.5200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3663
Cell Significance Index: -10.5000 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: -0.3674
Cell Significance Index: -3.7900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.3776
Cell Significance Index: -13.1200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3876
Cell Significance Index: -12.3500 - Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
Fold Change: -0.3909
Cell Significance Index: -2.6100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3995
Cell Significance Index: -13.0800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.4145
Cell Significance Index: -14.5200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3732004602
Symbol: CY561_HUMAN
Name: Cytochrome b-561
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7559396
Title: Genomic structure and expression of the human gene encoding cytochrome b561, an integral protein of the chromaffin granule membrane.
PubMed ID: 7559396
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7980462
Title: Human cytochrome b561: a revised hypothesis for conformation in membranes which reconciles sequence and functional information.
PubMed ID: 7980462
DOI: 10.1042/bj3030915
PubMed ID: 29343526
Title: Mutations in CYB561 causing a novel orthostatic hypotension syndrome.
PubMed ID: 29343526
Sequence Information:
- Length: 251
- Mass: 27559
- Checksum: 8EE53AE4D2569B77
- Sequence:
MEGGAAAATP TALPYYVAFS QLLGLTLVAM TGAWLGLYRG GIAWESDLQF NAHPLCMVIG LIFLQGNALL VYRVFRNEAK RTTKVLHGLL HIFALVIALV GLVAVFDYHR KKGYADLYSL HSWCGILVFV LYFVQWLVGF SFFLFPGASF SLRSRYRPQH IFFGATIFLL SVGTALLGLK EALLFNLGGK YSAFEPEGVL ANVLGLLLAC FGGAVLYILT RADWKRPSQA EEQALSMDFK TLTEGDSPGS Q
Genular Protein ID: 1385346022
Symbol: B3KTA1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 194
- Mass: 20528
- Checksum: 7EEE9BC93ABB4C0E
- Sequence:
MEGGAAAATP TALPYYVAFS QLLGLTLVAM TGAWLGLYRG GIAWESDLQF NAHPLCMVIG LIFLQGNALL VYRVFRNEAK RTTKVLHGLL HIFALVIALV GEFPDAAFPA TCLPLQAWWR CSTTTGRRAT LTCTAYTAGA GSLSLSCTLC SGWWASASSC SPELHSPCGA ATAHSTSSLV LPSSSFPWAP PCWA
Genular Protein ID: 2750768337
Symbol: J3QRH5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
Sequence Information:
- Length: 258
- Mass: 28267
- Checksum: A2BB84DC230DC9CA
- Sequence:
MSSVCLSMEG GAAAATPTAL PYYVAFSQLL GLTLVAMTGA WLGLYRGGIA WESDLQFNAH PLCMVIGLIF LQGNALLVYR VFRNEAKRTT KVLHGLLHIF ALVIALVGLV AVFDYHRKKG YADLYSLHSW CGILVFVLYF VQWLVGFSFF LFPGASFSLR SRYRPQHIFF GATIFLLSVG TALLGLKEAL LFNLGGKYSA FEPEGVLANV LGLLLACFGG AVLYILTRAD WKRPSQAEEQ ALSMDFKTLT EGDSPGSQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.