Details for: CYBA

Gene ID: 1535

Symbol: CYBA

Ensembl ID: ENSG00000051523

Description: cytochrome b-245 alpha chain

Associated with

Other Information

Genular Protein ID: 1696406250

Symbol: CY24A_HUMAN

Name: Cytochrome b-245 light chain

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 3368442

Title: Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.

PubMed ID: 3368442

DOI: 10.1073/pnas.85.10.3319

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2243141

Title: Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease.

PubMed ID: 2243141

DOI: 10.1172/jci114898

PubMed ID: 2469497

Title: Characterization of two monoclonal antibodies against cytochrome b558 of human neutrophils.

PubMed ID: 2469497

PubMed ID: 12716910

Title: Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases.

PubMed ID: 12716910

DOI: 10.1074/jbc.m212856200

PubMed ID: 15585859

Title: Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: characterization of six monoclonal antibodies to the p22phox subunit.

PubMed ID: 15585859

DOI: 10.4049/jimmunol.173.12.7349

PubMed ID: 15561711

Title: Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.

PubMed ID: 15561711

DOI: 10.1074/jbc.m407709200

PubMed ID: 15824103

Title: The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators.

PubMed ID: 15824103

DOI: 10.1074/jbc.m414548200

PubMed ID: 15927447

Title: Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases.

PubMed ID: 15927447

DOI: 10.1016/j.cellsig.2005.03.023

PubMed ID: 17140397

Title: Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3.

PubMed ID: 17140397

DOI: 10.1042/bj20060819

PubMed ID: 19948736

Title: Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding.

PubMed ID: 19948736

DOI: 10.1074/jbc.m109.030643

PubMed ID: 22808130

Title: Molecular interface of S100A8 with cytochrome b and NADPH oxidase activation.

PubMed ID: 22808130

DOI: 10.1371/journal.pone.0040277

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 16326715

Title: NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide.

PubMed ID: 16326715

DOI: 10.1074/jbc.m505193200

PubMed ID: 1415254

Title: Cytochrome b558-negative, autosomal recessive chronic granulomatous disease: two new mutations in the cytochrome b558 light chain of the NADPH oxidase (p22-phox).

PubMed ID: 1415254

PubMed ID: 1763037

Title: Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease.

PubMed ID: 1763037

DOI: 10.1073/pnas.88.24.11231

PubMed ID: 8168815

Title: Identification of allele-specific p22-phox mutations in a compound heterozygous patient with chronic granulomatous disease by mismatch PCR and restriction enzyme analysis.

PubMed ID: 8168815

DOI: 10.1007/bf00201671

PubMed ID: 7964505

Title: 156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox.

PubMed ID: 7964505

DOI: 10.1084/jem.180.6.2329

PubMed ID: 10910929

Title: Molecular analysis of 9 new families with chronic granulomatous disease caused by mutations in CYBA, the gene encoding p22(phox).

PubMed ID: 10910929

PubMed ID: 10759707

Title: Genetic studies of three Japanese patients with p22-phox-deficient chronic granulomatous disease: detection of a possible common mutant CYBA allele in Japan and a genotype-phenotype correlation in these patients.

PubMed ID: 10759707

DOI: 10.1046/j.1365-2141.2000.01857.x

PubMed ID: 10914676

Title: Statistical and mutational analysis of chronic granulomatous disease in Japan with special reference to gp91-phox and p22-phox deficiency.

PubMed ID: 10914676

DOI: 10.1007/s004390000288

PubMed ID: 18422995

Title: Characterization of six novel mutations in CYBA: the gene causing autosomal recessive chronic granulomatous disease.

PubMed ID: 18422995

DOI: 10.1111/j.1365-2141.2008.07148.x

PubMed ID: 19388116

Title: Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation.

PubMed ID: 19388116

DOI: 10.1002/humu.21029

PubMed ID: 23910690

Title: Clinical, functional, and genetic characterization of chronic granulomatous disease in 89 Turkish patients.

PubMed ID: 23910690

DOI: 10.1016/j.jaci.2013.05.039

Sequence Information:

  • Length: 195
  • Mass: 21013
  • Checksum: 428427AD19398240
  • Sequence:
  • MGQIEWAMWA NEQALASGLI LITGGIVATA GRFTQWYFGA YSIVAGVFVC LLEYPRGKRK 
    KGSTMERWGQ KYMTAVVKLF GPFTRNYYVR AVLHLLLSVP AGFLLATILG TACLAIASGI 
    YLLAAVRGEQ WTPIEPKPRE RPQIGGTIKQ PPSNPPPRPP AEARKKPSEE EAAVAAGGPP 
    GGPQVNPIPV TDEVV

Genular Protein ID: 633215633

Symbol: H3BNP7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

Sequence Information:

  • Length: 210
  • Mass: 22827
  • Checksum: 6E1F507E8B24CDB9
  • Sequence:
  • MGQIEWAMWA NEQALASGLI LITGGIVATA GRFTQWYFGA YSIVAGVFVC LLEYPRGKRK 
    KGSTMERWGQ KYMTAVVKLF GPFTRNYYVR AVLHLLLSVP AGFLLATILG TACLAIASGI 
    YLLSQVPPAR RGNCPPLAVR LLVCVRGKGA ALSVYAFRVW KWSSVSSLTD LPPAELSFRT 
    PSCCQVLIWA VALFSGGHPH PPRLPAATHS

Genular Protein ID: 4020219498

Symbol: B4DT46_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 131
  • Mass: 14019
  • Checksum: 0F8AF47330762B7F
  • Sequence:
  • MERWGQKHMT AVVKLFGPFT RNYYVRAVLH LLLSVPAGFL LATILGTACL AIASGIYLLA 
    AVRGEQWTPI EPKPRERPQI GGTIKQPPSN PPPRPPAEAR KKPSEEEAAV AAGGPPGGPQ 
    VNPIPVTDEV V

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.