Genular: Defining Cellular Identity and Function

Details for: Hmga2

Gene ID: 15364

Symbol: Hmga2

Ensembl ID: ENSMUSG00000056758

Description: high mobility group AT-hook 2

Associated with

Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular senescence
(R-MMU-2559583)
Dna damage/telomere stress induced senescence
(R-MMU-2559586)
Formation of senescence-associated heterochromatin foci (sahf)
(R-MMU-2559584)
5'-deoxyribose-5-phosphate lyase activity
(GO:0051575)
Adipose tissue development
(GO:0060612)
Adrenal gland development
(GO:0030325)
Astrocyte differentiation
(GO:0048708)
Base-excision repair
(GO:0006284)
C2h2 zinc finger domain binding
(GO:0070742)
Camp response element binding
(GO:0035497)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cell population proliferation
(GO:0008283)
Cell proliferation in forebrain
(GO:0021846)
Chondrocyte differentiation
(GO:0002062)
Chondrocyte proliferation
(GO:0035988)
Chromatin
(GO:0000785)
Chromosome condensation
(GO:0030261)
Dna-(apurinic or apyrimidinic site) endonuclease activity
(GO:0003906)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna binding
(GO:0003677)
Dna binding, bending
(GO:0008301)
Endodermal cell differentiation
(GO:0035987)
Enzyme binding
(GO:0019899)
Epithelial to mesenchymal transition
(GO:0001837)
Epithelial tube branching involved in lung morphogenesis
(GO:0060441)
Fat cell differentiation
(GO:0045444)
Fat pad development
(GO:0060613)
Fibroblast proliferation
(GO:0048144)
Heterochromatin formation
(GO:0031507)
Intracellular signal transduction
(GO:0035556)
Lung epithelium development
(GO:0060428)
Male germ cell nucleus
(GO:0001673)
Male gonad development
(GO:0008584)
Meiotic cell cycle
(GO:0051321)
Mesenchymal cell differentiation
(GO:0048762)
Mesodermal-endodermal cell signaling
(GO:0003131)
Mesodermal cell differentiation
(GO:0048333)
Mh1 domain binding
(GO:0035501)
Mh2 domain binding
(GO:0035500)
Minor groove of adenine-thymine-rich dna binding
(GO:0003680)
Multicellular organism growth
(GO:0035264)
Negative regulation by host of viral transcription
(GO:0043922)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of astrocyte differentiation
(GO:0048712)
Negative regulation of cellular senescence
(GO:2000773)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of dna binding
(GO:0043392)
Negative regulation of double-strand break repair via nonhomologous end joining
(GO:2001033)
Negative regulation of intracellular steroid hormone receptor signaling pathway
(GO:0033144)
Negative regulation of receptor signaling pathway via jak-stat
(GO:0046426)
Negative regulation of single stranded viral rna replication via double stranded dna intermediate
(GO:0045869)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of wnt signaling pathway
(GO:0030178)
Nuclear chromosome
(GO:0000228)
Nucleic acid binding
(GO:0003676)
Nucleosomal dna binding
(GO:0031492)
Nucleus
(GO:0005634)
Oncogene-induced cell senescence
(GO:0090402)
Pituitary gland development
(GO:0021983)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cell proliferation in bone marrow
(GO:0071864)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of epithelial cell proliferation involved in lung morphogenesis
(GO:0060501)
Positive regulation of fibroblast proliferation
(GO:0048146)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of multicellular organism growth
(GO:0040018)
Positive regulation of protein serine/threonine kinase activity
(GO:0071902)
Positive regulation of stem cell proliferation
(GO:2000648)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-dna complex
(GO:0032993)
Protein binding
(GO:0005515)
Regulation of cell cycle process
(GO:0010564)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of growth hormone secretion
(GO:0060123)
Regulation of peptide hormone secretion
(GO:0090276)
Regulation of stem cell population maintenance
(GO:2000036)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Senescence-associated heterochromatin focus
(GO:0035985)
Smad binding
(GO:0046332)
Smad protein complex
(GO:0071141)
Somatic stem cell population maintenance
(GO:0035019)
Spermatogenesis
(GO:0007283)
Stem cell proliferation
(GO:0072089)
Transcription cis-regulatory region binding
(GO:0000976)
Transcription coregulator activity
(GO:0003712)
Transcription corepressor activity
(GO:0003714)

Other Information

Proteins

High mobility group protein HMGI-C
Q6NSP9_MOUSE

Genular Protein ID: 2399089476

Symbol: HMGA2_MOUSE

Name: High mobility group protein HMGI-C

UniProtKB Accession Codes:

P52927 Q3UQW0

Database IDs:

Citations:

PubMed ID: 1762909

Title: cDNA cloning of the HMGI-C phosphoprotein, a nuclear protein associated with neoplastic and undifferentiated phenotypes.

PubMed ID: 1762909

DOI: 10.1093/nar/19.24.6793

PubMed ID: 8566786

Title: Isolation and characterization of the gene coding for murine high-mobility-group protein HMGI-C.

PubMed ID: 8566786

DOI: 10.1016/0378-1119(95)00666-4

PubMed ID: 8918814

Title: Genomic structure and expression of the murine Hmgi-c gene.

PubMed ID: 8918814

DOI: 10.1093/nar/24.20.4071

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14668482

Title: Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes.

PubMed ID: 14668482

DOI: 10.1091/mbc.e03-09-0638

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27446912

Title: Gene expression profiling of muscle stem cells identifies novel regulators of postnatal myogenesis.

PubMed ID: 27446912

DOI: 10.3389/fcell.2016.00058

Sequence Information:

Length: 108
Mass: 11819
Checksum: 40A3E38F62268C09
Sequence:

MSARGEGAGQ PSTSAQGQPA APVPQKRGRG RPRKQQQEPT CEPSPKRPRG RPKGSKNKSP 
SKAAQKKAET IGEKRPRGRP RKWPQQVVQK KPAQETEETS SQESAEED

Genular Protein ID: 69123852

Symbol: Q6NSP9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q6NSP9

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 129
Mass: 14055
Checksum: 02CEDABDEC2372D2
Sequence:

MSARGEGAGQ PSTSAQGQPA APVPQKRGRG RPRKQQQEPT CEPSPKRPRG RPKGSKNKSP 
SKAAQKKAET IGEKRPRGRP RKWPQQVVQK KPAQGGEFGE RTRCHESQTS SLPHNPYGQE 
LIASTLMGD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hmga2

Associated with

Other Information

cDNA cloning of the HMGI-C phosphoprotein, a nuclear protein associated with neoplastic and undifferentiated phenotypes. PubMed ID: 1762909

Isolation and characterization of the gene coding for murine high-mobility-group protein HMGI-C. PubMed ID: 8566786

Genomic structure and expression of the murine Hmgi-c gene. PubMed ID: 8918814

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes. PubMed ID: 14668482

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Gene expression profiling of muscle stem cells identifies novel regulators of postnatal myogenesis. PubMed ID: 27446912

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Database document:

PubMed ID: 1762909

PubMed ID: 8566786

PubMed ID: 8918814

PubMed ID: 16141072

PubMed ID: 15489334

PubMed ID: 14668482

PubMed ID: 19131326

PubMed ID: 21183079

PubMed ID: 27446912

PubMed ID: 15489334

PubMed ID: 19468303