Details for: Hmx2

Gene ID: 15372

Symbol: Hmx2

Ensembl ID: ENSMUSG00000050100

Description: H6 homeobox 2

Associated with

  • Brain development
    (GO:0007420)
  • Cell differentiation
    (GO:0030154)
  • Cell population proliferation
    (GO:0008283)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Epithelial cell proliferation
    (GO:0050673)
  • Inner ear morphogenesis
    (GO:0042472)
  • Multicellular organism development
    (GO:0007275)
  • Nervous system development
    (GO:0007399)
  • Nucleus
    (GO:0005634)
  • Positive regulation of epithelial cell proliferation
    (GO:0050679)
  • Positive regulation of mrna splicing, via spliceosome
    (GO:0048026)
  • Positive regulation of stem cell proliferation
    (GO:2000648)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Stem cell proliferation
    (GO:0072089)

Other Information

Genular Protein ID: 3715689937

Symbol: HMX2_MOUSE

Name: Homeobox protein HMX2

UniProtKB Accession Codes:

P43687 Q3UUN6 Q8R1Q2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 3 Ensembl 2 GO 14 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8541222

Title: Distinct temporal expression of mouse Nkx-5.1 and Nkx-5.2 homeobox genes during brain and ear development.

PubMed ID: 8541222

DOI: 10.1016/0925-4773(95)00414-v

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7510254

Title: A novel NK-related mouse homeobox gene: expression in central and peripheral nervous structures during embryonic development.

PubMed ID: 7510254

DOI: 10.1006/dbio.1994.1086

PubMed ID: 11748138

Title: Hmx2 homeobox gene control of murine vestibular morphogenesis.

PubMed ID: 11748138

DOI: 10.1242/dev.128.24.5017

PubMed ID: 15363417

Title: Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx.

PubMed ID: 15363417

DOI: 10.1016/j.devcel.2004.06.016

Sequence Information:

  • Length: 273
  • Mass: 29634
  • Checksum: 19F9F0E1A92A5644
  • Sequence:
    • MGSKEDVGKG CPAAGGVSSF TIQSILGGGP SEAPREPAGW PARKRSLSVS SEEEEPEEGW 
KAPACFCPDP HGPKEPSPKH HTPIPFPCLG TPKGSGGAGP AASERTPFLS PSHPDFKEEK 
ERLLPAGSPS PGPERPRDGG AERQTGAAKK KTRTVFSRSQ VYQLESTFDM KRYLSSSERA 
CLASSLQLTE TQVKTWFQNR RNKWKRQLSA ELEAANMAHA SAQTLVGMPL VFRDSSLLRV 
PVPRSLAFPA PLYYPSSNLS ALPLYNLYNK LDY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.