Details for: Hoxb8

Gene ID: 15416

Symbol: Hoxb8

Ensembl ID: ENSMUSG00000056648

Description: homeobox B8

Associated with

  • Adult locomotory behavior
    (GO:0008344)
  • Anterior/posterior pattern specification
    (GO:0009952)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Dorsal spinal cord development
    (GO:0021516)
  • Embryonic skeletal system morphogenesis
    (GO:0048704)
  • Grooming behavior
    (GO:0007625)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of myeloid cell differentiation
    (GO:0045638)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Protein binding
    (GO:0005515)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sensory perception of pain
    (GO:0019233)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Skeletal system morphogenesis
    (GO:0048705)

Other Information

Genular Protein ID: 2906328816

Symbol: HXB8_MOUSE

Name: Homeobox protein Hox-B8

UniProtKB Accession Codes:

P09632

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DIP 1 DNASU 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 17 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 4 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2564662

Title: Expression of Hox-2.4 homeobox gene directed by proviral insertion in a myeloid leukemia.

PubMed ID: 2564662

DOI: 10.1093/nar/17.5.1881

PubMed ID: 2907477

Title: DNA rearrangement of a homeobox gene in myeloid leukaemic cells.

PubMed ID: 2907477

DOI: 10.1002/j.1460-2075.1988.tb03326.x

PubMed ID: 1673811

Title: A deletion and a rearrangement distinguish between the intracisternal A- particle of Hox-2.4 and that of interleukin-3 in the same leukemic cells.

PubMed ID: 1673811

DOI: 10.1016/0042-6822(91)90686-6

PubMed ID: 2891608

Title: Sequence analysis of the murine Hox-2.2, -2.3, and -2.4 homeo boxes: evolutionary and structural comparisons.

PubMed ID: 2891608

DOI: 10.1016/0888-7543(87)90011-5

PubMed ID: 7791786

Title: Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.

PubMed ID: 7791786

DOI: 10.1128/mcb.15.7.3786

Sequence Information:

  • Length: 243
  • Mass: 27618
  • Checksum: 368964C77884D21F
  • Sequence:
    • MSSYFVNSLF SKYKTGESLR PNYYDCGFAQ DLGGRPTVVY GPSSGGSFQH PSQIQEFYHG 
PSSLSTAPYQ QNPCAVACHG DPGNFYGYDP LQRQSLFGAQ DPDLVQYADC KLAAASGLGE 
EAEGSEQSPS PTQLFPWMRP QAAAGRRRGR QTYSRYQTLE LEKEFLFNPY LTRKRRIEVS 
HALGLTERQV KIWFQNRRMK WKKENNKDKF PSSKCEQEEL EKEKLERAPE TAEQGDAQKG 
DKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.