Details for: CYP1A1
Associated with
Other Information
Genular Protein ID: 1002409985
Symbol: CP1A1_HUMAN
Name: Cytochrome P450 form 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2989797
Title: Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism.
PubMed ID: 2989797
PubMed ID: 3838385
Title: Human dioxin-inducible cytochrome P1-450: complementary DNA and amino acid sequence.
PubMed ID: 3838385
PubMed ID: 3019683
Title: Structure and drug inducibility of the human cytochrome P-450c gene.
PubMed ID: 3019683
PubMed ID: 11207026
Title: Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.
PubMed ID: 11207026
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9500998
Title: Identification of cytochrome P450 1A1 in human brain.
PubMed ID: 9500998
PubMed ID: 3000715
Title: Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.
PubMed ID: 3000715
PubMed ID: 10681376
Title: Biosynthesis of all-trans-retinoic acid from all-trans-retinol: catalysis of all-trans-retinol oxidation by human P-450 cytochromes.
PubMed ID: 10681376
PubMed ID: 11555828
Title: Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol.
PubMed ID: 11555828
PubMed ID: 14559847
Title: Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol.
PubMed ID: 14559847
PubMed ID: 12865317
Title: Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.
PubMed ID: 12865317
DOI: 10.1210/en.2003-0192
PubMed ID: 15041462
Title: Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid.
PubMed ID: 15041462
PubMed ID: 15805301
Title: Association of CYP1A1 polymorphisms with differential metabolic activation of 17beta-estradiol and estrone.
PubMed ID: 15805301
PubMed ID: 18577768
Title: Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism.
PubMed ID: 18577768
PubMed ID: 19965576
Title: Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450.
PubMed ID: 19965576
DOI: 10.1194/jlr.m003061
PubMed ID: 20972997
Title: Analysis of epoxyeicosatrienoic acids by chiral liquid chromatography/electron capture atmospheric pressure chemical ionization mass spectrometry using [13C]-analog internal standards.
PubMed ID: 20972997
DOI: 10.1002/rcm.4760
PubMed ID: 21068195
Title: Human CYP2S1 metabolizes cyclooxygenase- and lipoxygenase-derived eicosanoids.
PubMed ID: 21068195
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 23508959
Title: Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism.
PubMed ID: 23508959
PubMed ID: 1722803
Title: Genetic linkage of lung cancer-associated MspI polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P450IA1 gene.
PubMed ID: 1722803
PubMed ID: 8895751
Title: A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility.
PubMed ID: 8895751
PubMed ID: 10739168
Title: Variation in induced CYP1A1 levels: relationship to CYP1A1, Ah receptor and GSTM1 polymorphisms.
PubMed ID: 10739168
PubMed ID: 11295847
Title: Detection of known and two novel (M331I and R464S) missense mutations in the human CYP1A1 gene in a French Caucasian population.
PubMed ID: 11295847
DOI: 10.1002/humu.49
PubMed ID: 15618738
Title: Novel nonsynonymous polymorphisms of the CYP1A1 Gene in Japanese.
PubMed ID: 15618738
DOI: 10.2133/dmpk.18.218
PubMed ID: 15469410
Title: Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.
PubMed ID: 15469410
PubMed ID: 15643613
Title: Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus.
PubMed ID: 15643613
DOI: 10.1002/humu.20134
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 512
- Mass: 58165
- Checksum: 3C62366044148EFD
- Sequence:
MLFPISMSAT EFLLASVIFC LVFWVIRASR PQVPKGLKNP PGPWGWPLIG HMLTLGKNPH LALSRMSQQY GDVLQIRIGS TPVVVLSGLD TIRQALVRQG DDFKGRPDLY TFTLISNGQS MSFSPDSGPV WAARRRLAQN GLKSFSIASD PASSTSCYLE EHVSKEAEVL ISTLQELMAG PGHFNPYRYV VVSVTNVICA ICFGRRYDHN HQELLSLVNL NNNFGEVVGS GNPADFIPIL RYLPNPSLNA FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV IGRSRRPRLS DRSHLPYMEA FILETFRHSS FVPFTIPHST TRDTSLKGFY IPKGRCVFVN QWQINHDQKL WVNPSEFLPE RFLTPDGAID KVLSEKVIIF GMGKRKCIGE TIARWEVFLF LAILLQRVEF SVPLGVKVDM TPIYGLTMKH ACCEHFQMQL RS
Genular Protein ID: 2440584349
Symbol: E7EMT5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 483
- Mass: 54800
- Checksum: 6DC7808EA30FACB1
- Sequence:
MLFPISMSAT EFLLASVIFC LVFWVIRASR PQVPKGLKNP PGPWGWPLIG HMLTLGKNPH LALSRMSQQY GDVLQIRIGS TPVVVLSGLD TIRQALVRQG DDFKGRPDLY TFTLISNGQS MSFSPDSGPV WAARRRLAQN GLKSFSIASD PASSTSCYLE EHVSKEAEVL ISTLQELMAG PGHFNPYRYV VVSVTNVICA ICFGRRYDHN HQELLSLVNL NNNFGEVVGS GNPADFIPIL RYLPNPSLNA FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV IGRSRRPRLS DRSHLPYMEA FILETFRHSS FVPFTIPHRK LWVNPSEFLP ERFLTPDGAI DKVLSEKVII FGMGKRKCIG ETIARWEVFL FLAILLQRVE FSVPLGVKVD MTPIYGLTMK HACCEHFQMQ LRS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.