Details for: Hoxd4

Gene ID: 15436

Symbol: Hoxd4

Ensembl ID: ENSMUSG00000101174

Description: homeobox D4

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Cell junction
    (GO:0030054)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Embryonic skeletal system morphogenesis
    (GO:0048704)
  • Multicellular organism development
    (GO:0007275)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Stem cell differentiation
    (GO:0048863)

Other Information

Genular Protein ID: 1170778077

Symbol: HXD4_MOUSE

Name: Homeobox protein Hox-D4

UniProtKB Accession Codes:

P10628 A2ASN3 P97451 Q3UXL6

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 5 Ensembl 2 GO 11 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PIR 2 PRINTS 2 PRO 1 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 2898782

Title: Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.

PubMed ID: 2898782

DOI: 10.1073/pnas.85.13.4760

PubMed ID: 7907418

Title: A proline-rich transcriptional activation domain in murine HOXD-4 (HOX-4.2).

PubMed ID: 7907418

DOI: 10.1093/nar/22.3.376

PubMed ID: 9360992

Title: Characterization and retinoic acid responsiveness of the murine Hoxd4 transcription unit.

PubMed ID: 9360992

DOI: 10.1074/jbc.272.46.29151

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 1348361

Title: Hox-1.11 and Hox-4.9 homeobox genes.

PubMed ID: 1348361

DOI: 10.1073/pnas.89.7.2883

PubMed ID: 7791786

Title: Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.

PubMed ID: 7791786

DOI: 10.1128/mcb.15.7.3786

Sequence Information:

  • Length: 250
  • Mass: 27371
  • Checksum: 2B20A00BAD1B8757
  • Sequence:
    • MAMSSYMVNS KYVDPKFPPC EEYLQGGYLG EQGADYYGSG AQGADFQPSG LYPRPDFGEQ 
PFGGGGPGPG SALPARGHGQ EPSGPGSHYG APGERCPAPP PAPLPGARAC SQPTGPKQPP 
PGTALKQPAV VYPWMKKVHV NSVNPNYTGG EPKRSRTAYT RQQVLELEKE FHFNRYLTRR 
RRIEIAHTLC LSERQIKIWF QNRRMKWKKD HKLPNTKGRS SSSSSCSSSA APGQHLQPMA 
KDHHTDLTTL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.