No CSI details found for gene ID: 1544
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 2226361328
Symbol: CP1A2_HUMAN
Name: CYPIA2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3755823
Title: Human P3(450): cDNA and complete amino acid sequence.
PubMed ID: 3755823
PubMed ID: 3462722
Title: Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA.
PubMed ID: 3462722
PubMed ID: 2575218
Title: Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression.
PubMed ID: 2575218
PubMed ID: 3681487
Title: Human P(3)450: cDNA and complete protein sequence, repetitive Alu sequences in the 3' nontranslated region, and localization of gene to chromosome 15.
PubMed ID: 3681487
PubMed ID: 11207026
Title: Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.
PubMed ID: 11207026
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3517618
Title: Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat.
PubMed ID: 3517618
PubMed ID: 3000715
Title: Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.
PubMed ID: 3000715
PubMed ID: 9435160
Title: Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes.
PubMed ID: 9435160
PubMed ID: 10681376
Title: Biosynthesis of all-trans-retinoic acid from all-trans-retinol: catalysis of all-trans-retinol oxidation by human P-450 cytochromes.
PubMed ID: 10681376
PubMed ID: 11555828
Title: Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol.
PubMed ID: 11555828
PubMed ID: 12865317
Title: Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.
PubMed ID: 12865317
DOI: 10.1210/en.2003-0192
PubMed ID: 14725854
Title: Functional characterization of four allelic variants of human cytochrome P450 1A2.
PubMed ID: 14725854
PubMed ID: 19965576
Title: Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450.
PubMed ID: 19965576
DOI: 10.1194/jlr.m003061
PubMed ID: 21068195
Title: Human CYP2S1 metabolizes cyclooxygenase- and lipoxygenase-derived eicosanoids.
PubMed ID: 21068195
PubMed ID: 21576599
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26988023
Title: Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.
PubMed ID: 26988023
DOI: 10.1038/ncomms11030
PubMed ID: 17311915
Title: Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2.
PubMed ID: 17311915
PubMed ID: 9884316
Title: Detection of a novel cytochrome P-450 1A2 polymorphism (F21L) in Chinese.
PubMed ID: 9884316
PubMed ID: 11295848
Title: Five novel natural allelic variants-951A->C, 1042G->A (D348N), 1156A->T (I386F), 1217G->A (C406Y) and 1291C->T (C431Y)-of the human CYP1A2 gene in a French Caucasian population.
PubMed ID: 11295848
PubMed ID: 14563787
Title: Six novel nonsynonymous CYP1A2 gene polymorphisms: catalytic activities of the naturally occurring variant enzymes.
PubMed ID: 14563787
PubMed ID: 15469410
Title: Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.
PubMed ID: 15469410
PubMed ID: 15770072
Title: Single nucleotide polymorphisms and haplotypes of CYP1A2 in a Japanese population.
PubMed ID: 15770072
DOI: 10.2133/dmpk.20.24
PubMed ID: 15643613
Title: Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus.
PubMed ID: 15643613
DOI: 10.1002/humu.20134
PubMed ID: 16522833
Title: Coffee, CYP1A2 genotype, and risk of myocardial infarction.
PubMed ID: 16522833
Sequence Information:
- Length: 516
- Mass: 58407
- Checksum: 8557AB02860C4806
- Sequence:
MALSQSVPFS ATELLLASAI FCLVFWVLKG LRPRVPKGLK SPPEPWGWPL LGHVLTLGKN PHLALSRMSQ RYGDVLQIRI GSTPVLVLSR LDTIRQALVR QGDDFKGRPD LYTSTLITDG QSLTFSTDSG PVWAARRRLA QNALNTFSIA SDPASSSSCY LEEHVSKEAK ALISRLQELM AGPGHFDPYN QVVVSVANVI GAMCFGQHFP ESSDEMLSLV KNTHEFVETA SSGNPLDFFP ILRYLPNPAL QRFKAFNQRF LWFLQKTVQE HYQDFDKNSV RDITGALFKH SKKGPRASGN LIPQEKIVNL VNDIFGAGFD TVTTAISWSL MYLVTKPEIQ RKIQKELDTV IGRERRPRLS DRPQLPYLEA FILETFRHSS FLPFTIPHST TRDTTLNGFY IPKKCCVFVN QWQVNHDPEL WEDPSEFRPE RFLTADGTAI NKPLSEKMML FGMGKRRCIG EVLAKWEIFL FLAILLQQLE FSVPPGVKVD LTPIYGLTMK HARCEHVQAR LRFSIN
Details Unavailable
Detailed CSI data for this gene is not available. You will be redirected to a page with all available raw data in 3 seconds.
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{
"geneID": 1544,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AC091230.23"
]
},
"genePos": {
"start": 31304,
"end": 39066
},
"orientation": false,
"symbol": "CYP1A2",
"created": {
"$date": {
"$numberLong": "1738333348759"
}
},
"crossReference": {
"enseGeneID": "ENSG00000140505",
"enseRnaID": [
"ENST00000343932.5"
],
"enseProtID": [
"ENSP00000342007.4"
]
},
"chrom": {
"pos": "15",
"type": 1,
"loc": "15q24.1"
},
"desc": "cytochrome P450 family 1 subfamily A member 2",
"geneType": 5,
"mim": [
{
"id": 124060,
"relation": 0
}
],
"ontology": [
{
"id": "R-HSA-1430728",
"term": "Metabolism",
"cat": 10
},
{
"id": "R-HSA-211859",
"term": "Biological oxidations",
"cat": 11
},
{
"id": "R-HSA-556833",
"term": "Metabolism of lipids",
"cat": 11
},
{
"id": "R-HSA-156580",
"term": "Phase II - Conjugation of compounds",
"cat": 12
},
{
"id": "R-HSA-211945",
"term": "Phase I - Functionalization of compounds",
"cat": 12
},
{
"id": "R-HSA-5423646",
"term": "Aflatoxin activation and detoxification",
"cat": 12
},
{
"id": "R-HSA-8978868",
"term": "Fatty acid metabolism",
"cat": 12
},
{
"id": "R-HSA-9018678",
"term": "Biosynthesis of specialized proresolving mediators (SPMs)",
"cat": 12
},
{
"id": "R-HSA-156581",
"term": "Methylation",
"cat": 13
},
{
"id": "R-HSA-211897",
"term": "Cytochrome P450 - arranged by substrate type",
"cat": 13
},
{
"id": "R-HSA-2142753",
"term": "Arachidonate metabolism",
"cat": 13
},
{
"id": "R-HSA-9018677",
"term": "Biosynthesis of DHA-derived SPMs",
"cat": 13
},
{
"id": "R-HSA-211981",
"term": "Xenobiotics",
"cat": 14
},
{
"id": "R-HSA-2142670",
"term": "Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)",
"cat": 14
},
{
"id": "R-HSA-2142816",
"term": "Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)",
"cat": 14
},
{
"id": "R-HSA-9018681",
"term": "Biosynthesis of protectins",
"cat": 14
},
{
"id": "R-HSA-9018682",
"term": "Biosynthesis of maresins",
"cat": 14
},
{
"id": "R-HSA-211957",
"term": "Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2",
"cat": 15
},
{
"id": "R-HSA-9027307",
"term": "Biosynthesis of maresin-like SPMs",
"cat": 15
},
{
"id": "GO:0004497",
"term": "monooxygenase activity",
"cat": 0
},
{
"id": "GO:0004497",
"term": "monooxygenase activity",
"pubMed": [
15327587,
19651758
],
"cat": 0
},
{
"id": "GO:0005506",
"term": "iron ion binding",
"cat": 0
},
{
"id": "GO:0005515",
"term": "protein binding",
"pubMed": [
26988023,
32296183
],
"cat": 0
},
{
"id": "GO:0009055",
"term": "electron transfer activity",
"pubMed": [
2813353
],
"cat": 0
},
{
"id": "GO:0016491",
"term": "oxidoreductase activity",
"pubMed": [
16401082,
19219744
],
"cat": 0
},
{
"id": "GO:0016712",
"term": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen",
"pubMed": [
2813353
],
"cat": 0
},
{
"id": "GO:0019899",
"term": "enzyme binding",
"pubMed": [
15680923
],
"cat": 0
},
{
"id": "GO:0020037",
"term": "heme binding",
"pubMed": [
17311915
],
"cat": 0
},
{
"id": "GO:0032451",
"term": "demethylase activity",
"pubMed": [
2813353
],
"cat": 0
},
{
"id": "GO:0034875",
"term": "caffeine oxidase activity",
"pubMed": [
18619574
],
"cat": 0
},
{
"id": "GO:0070330",
"term": "aromatase activity",
"cat": 0
},
{
"id": "GO:0101020",
"term": "estrogen 16-alpha-hydroxylase activity",
"pubMed": [
11555828
],
"cat": 0
},
{
"id": "GO:0101021",
"term": "estrogen 2-hydroxylase activity",
"pubMed": [
11555828,
12865317
],
"cat": 0
},
{
"id": "GO:0106256",
"term": "hydroperoxy icosatetraenoate dehydratase activity",
"cat": 0
},
{
"id": "GO:0006706",
"term": "steroid catabolic process",
"pubMed": [
18356043
],
"cat": 1
},
{
"id": "GO:0006778",
"term": "porphyrin-containing compound metabolic process",
"cat": 1
},
{
"id": "GO:0006805",
"term": "xenobiotic metabolic process",
"pubMed": [
15327587,
19219744
],
"cat": 1
},
{
"id": "GO:0006805",
"term": "xenobiotic metabolic process",
"cat": 1
},
{
"id": "GO:0008203",
"term": "cholesterol metabolic process",
"cat": 1
},
{
"id": "GO:0008210",
"term": "estrogen metabolic process",
"pubMed": [
11555828,
12865317
],
"cat": 1
},
{
"id": "GO:0009403",
"term": "toxin biosynthetic process",
"pubMed": [
11511187
],
"cat": 1
},
{
"id": "GO:0009791",
"term": "post-embryonic development",
"cat": 1
},
{
"id": "GO:0009820",
"term": "alkaloid metabolic process",
"pubMed": [
11511187
],
"cat": 1
},
{
"id": "GO:0010468",
"term": "regulation of gene expression",
"cat": 1
},
{
"id": "GO:0016098",
"term": "monoterpenoid metabolic process",
"pubMed": [
16401082
],
"cat": 1
},
{
"id": "GO:0018894",
"term": "dibenzo-p-dioxin metabolic process",
"cat": 1
},
{
"id": "GO:0019373",
"term": "epoxygenase P450 pathway",
"cat": 1
},
{
"id": "GO:0030324",
"term": "lung development",
"cat": 1
},
{
"id": "GO:0032259",
"term": "methylation",
"cat": 1
},
{
"id": "GO:0032787",
"term": "monocarboxylic acid metabolic process",
"pubMed": [
19651758
],
"cat": 1
},
{
"id": "GO:0042178",
"term": "xenobiotic catabolic process",
"pubMed": [
18619574
],
"cat": 1
},
{
"id": "GO:0042178",
"term": "xenobiotic catabolic process",
"pubMed": [
18356043
],
"cat": 1
},
{
"id": "GO:0042572",
"term": "retinol metabolic process",
"pubMed": [
10681376
],
"cat": 1
},
{
"id": "GO:0042572",
"term": "retinol metabolic process",
"cat": 1
},
{
"id": "GO:0042759",
"term": "long-chain fatty acid biosynthetic process",
"cat": 1
},
{
"id": "GO:0045333",
"term": "cellular respiration",
"cat": 1
},
{
"id": "GO:0046222",
"term": "aflatoxin metabolic process",
"cat": 1
},
{
"id": "GO:0050665",
"term": "hydrogen peroxide biosynthetic process",
"cat": 1
},
{
"id": "GO:0070989",
"term": "oxidative demethylation",
"pubMed": [
18619574
],
"cat": 1
},
{
"id": "GO:0071276",
"term": "cellular response to cadmium ion",
"cat": 1
},
{
"id": "GO:0097267",
"term": "omega-hydroxylase P450 pathway",
"cat": 1
},
{
"id": "GO:0005789",
"term": "endoplasmic reticulum membrane",
"cat": 2
},
{
"id": "GO:0043231",
"term": "intracellular membrane-bounded organelle",
"cat": 2
},
{
"id": "GO:0043231",
"term": "intracellular membrane-bounded organelle",
"pubMed": [
2813353
],
"cat": 2
}
],
"protein": [
{
"symbol": "CP1A2_HUMAN",
"name": "CYPIA2",
"accession": [
"P05177",
"Q16754",
"Q6NWU3",
"Q6NWU5",
"Q9BXX7",
"Q9UK49"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"Rhea": [
"RHEA:17149",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:17150",
"RHEA:47212",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:47213",
"RHEA:47280",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:47281",
"RHEA:47208",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:47209",
"RHEA:47292",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:47293",
"RHEA:50256",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:50257",
"RHEA:42092",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:42093",
"RHEA:42088",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:42089",
"RHEA:49860",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:49861",
"RHEA:49856",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:49857",
"RHEA:39779",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:39780",
"RHEA:52120",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:52121",
"RHEA:48632",
"RHEA:48633",
"RHEA:37947",
"RHEA:37948",
"RHEA:48636",
"RHEA:48637",
"RHEA:48716",
"RHEA:48717",
"RHEA:52292",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:52293",
"RHEA:39759",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:39760",
"RHEA:52284",
"RHEA-COMP:11964",
"RHEA-COMP:11965",
"RHEA:52285"
],
"ChEBI": [
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:30879",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:142491",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:16469",
"CHEBI:28744",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:16469",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:62845",
"CHEBI:1156",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:17263",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:17263",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:87602",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:16113",
"CHEBI:42977",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:17336",
"CHEBI:17898",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:17898",
"CHEBI:35291",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:32395",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:131965",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:32395",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:131964",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:58562",
"CHEBI:76634",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:77016",
"CHEBI:136410",
"CHEBI:15377",
"CHEBI:57450",
"CHEBI:65342",
"CHEBI:15377",
"CHEBI:57444",
"CHEBI:75231",
"CHEBI:15377",
"CHEBI:57410",
"CHEBI:57446",
"CHEBI:15377",
"CHEBI:57466",
"CHEBI:90781",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:32395",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:136524",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:32395",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:76627",
"CHEBI:15377",
"CHEBI:15378",
"CHEBI:15379",
"CHEBI:30245",
"CHEBI:57618",
"CHEBI:58210",
"CHEBI:136522",
"CHEBI:30413",
"CHEBI:30413",
"CHEBI:18248"
],
"EC": [
"1.14.14.1",
"4.2.1.152"
],
"EMBL": [
"Z00036",
"M55053",
"M12078",
"L00389",
"L00384",
"L00385",
"L00386",
"L00388",
"L00387",
"M31667",
"M31664",
"M31665",
"M31666",
"AF182274",
"AF253322",
"DQ022432",
"BC067424",
"BC067425",
"BC067426",
"BC067427",
"BC067428",
"BC067429"
],
"CCDS": [
"CCDS32293.1"
],
"PIR": [
"S16718"
],
"RefSeq": [
"NP_000752.2"
],
"PDB": [
"2HI4"
],
"PDBsum": [
"2HI4"
],
"AlphaFoldDB": [
"P05177"
],
"SMR": [
"P05177"
],
"BioGRID": [
"107924"
],
"IntAct": [
"P05177"
],
"STRING": [
"9606.ENSP00000342007"
],
"BindingDB": [
"P05177"
],
"ChEMBL": [
"CHEMBL3356"
],
"DrugBank": [
"DB08496",
"DB01667",
"DB14132",
"DB04356",
"DB02489",
"DB11932",
"DB12001",
"DB05812",
"DB13573",
"DB01418",
"DB00316",
"DB15568",
"DB06594",
"DB00518",
"DB05396",
"DB00969",
"DB07453",
"DB01424",
"DB01223",
"DB01118",
"DB00321",
"DB00261",
"DB01217",
"DB01435",
"DB06605",
"DB05676",
"DB06413",
"DB06216",
"DB01072",
"DB15011",
"DB06442",
"DB06626",
"DB00993",
"DB00972",
"DB13203",
"DB05015",
"DB16703",
"DB06769",
"DB01086",
"DB06770",
"DB06771",
"DB06732",
"DB00195",
"DB04889",
"DB11967",
"DB13975",
"DB00188",
"DB12151",
"DB01558",
"DB14018",
"DB13812",
"DB00201",
"DB09061",
"DB14737",
"DB11791",
"DB06774",
"DB00564",
"DB06016",
"DB01136",
"DB12814",
"DB00477",
"DB00356",
"DB01166",
"DB00501",
"DB01012",
"DB00568",
"DB00827",
"DB00537",
"DB00215",
"DB12499",
"DB14025",
"DB00349",
"DB01242",
"DB00575",
"DB00758",
"DB00363",
"DB00286",
"DB11672",
"DB14635",
"DB00924",
"DB08912",
"DB00851",
"DB06292",
"DB01254",
"DB01609",
"DB01151",
"DB16650",
"DB12161",
"DB01191",
"DB00633",
"DB11994",
"DB00586",
"DB11511",
"DB12945",
"DB00280",
"DB01184",
"DB09167",
"DB05928",
"DB01142",
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"title": "Human P3(450): cDNA and complete amino acid sequence.",
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"title": "Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA.",
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"doi": "10.1073\/pnas.83.18.6731"
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"title": "Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression.",
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"doi": "10.1210\/mend-3-9-1399"
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"title": "Human P(3)450: cDNA and complete protein sequence, repetitive Alu sequences in the 3' nontranslated region, and localization of gene to chromosome 15.",
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"title": "Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.",
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"doi": "10.1097\/00008571-200102000-00001"
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{
"title": "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).",
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"doi": "10.1101\/gr.2596504"
},
{
"title": "Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat.",
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{
"title": "Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.",
"pubmedID": "3000715",
"doi": "10.1089\/dna.1985.4.395"
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{
"title": "Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes.",
"pubmedID": "9435160"
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{
"title": "Biosynthesis of all-trans-retinoic acid from all-trans-retinol: catalysis of all-trans-retinol oxidation by human P-450 cytochromes.",
"pubmedID": "10681376"
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{
"title": "Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol.",
"pubmedID": "11555828",
"doi": "10.1053\/meta.2001.25592"
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{
"title": "Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.",
"pubmedID": "12865317",
"doi": "10.1210\/en.2003-0192"
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{
"title": "Functional characterization of four allelic variants of human cytochrome P450 1A2.",
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"doi": "10.1016\/j.abb.2003.11.019"
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{
"title": "Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450.",
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"doi": "10.1194\/jlr.m003061"
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{
"title": "Human CYP2S1 metabolizes cyclooxygenase- and lipoxygenase-derived eicosanoids.",
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"doi": "10.1124\/dmd.110.035121"
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{
"title": "Cholesterol 25-hydroxylation activity of CYP3A.",
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"doi": "10.1194\/jlr.m014084"
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{
"title": "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.",
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"title": "Haem-dependent dimerization of PGRMC1\/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.",
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"title": "Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2.",
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"title": "Detection of a novel cytochrome P-450 1A2 polymorphism (F21L) in Chinese.",
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{
"title": "Five novel natural allelic variants-951A->C, 1042G->A (D348N), 1156A->T (I386F), 1217G->A (C406Y) and 1291C->T (C431Y)-of the human CYP1A2 gene in a French Caucasian population.",
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"title": "Six novel nonsynonymous CYP1A2 gene polymorphisms: catalytic activities of the naturally occurring variant enzymes.",
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"title": "Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.",
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"title": "Single nucleotide polymorphisms and haplotypes of CYP1A2 in a Japanese population.",
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"title": "Coffee, CYP1A2 genotype, and risk of myocardial infarction.",
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