Details for: CYP1A2
Associated with
Other Information
Genular Protein ID: 2226361328
Symbol: CP1A2_HUMAN
Name: CYPIA2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3755823
Title: Human P3(450): cDNA and complete amino acid sequence.
PubMed ID: 3755823
PubMed ID: 3462722
Title: Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA.
PubMed ID: 3462722
PubMed ID: 2575218
Title: Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression.
PubMed ID: 2575218
PubMed ID: 3681487
Title: Human P(3)450: cDNA and complete protein sequence, repetitive Alu sequences in the 3' nontranslated region, and localization of gene to chromosome 15.
PubMed ID: 3681487
PubMed ID: 11207026
Title: Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.
PubMed ID: 11207026
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3517618
Title: Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat.
PubMed ID: 3517618
PubMed ID: 3000715
Title: Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.
PubMed ID: 3000715
PubMed ID: 9435160
Title: Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes.
PubMed ID: 9435160
PubMed ID: 10681376
Title: Biosynthesis of all-trans-retinoic acid from all-trans-retinol: catalysis of all-trans-retinol oxidation by human P-450 cytochromes.
PubMed ID: 10681376
PubMed ID: 11555828
Title: Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol.
PubMed ID: 11555828
PubMed ID: 12865317
Title: Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.
PubMed ID: 12865317
DOI: 10.1210/en.2003-0192
PubMed ID: 14725854
Title: Functional characterization of four allelic variants of human cytochrome P450 1A2.
PubMed ID: 14725854
PubMed ID: 19965576
Title: Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450.
PubMed ID: 19965576
DOI: 10.1194/jlr.m003061
PubMed ID: 21068195
Title: Human CYP2S1 metabolizes cyclooxygenase- and lipoxygenase-derived eicosanoids.
PubMed ID: 21068195
PubMed ID: 21576599
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26988023
Title: Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.
PubMed ID: 26988023
DOI: 10.1038/ncomms11030
PubMed ID: 17311915
Title: Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2.
PubMed ID: 17311915
PubMed ID: 9884316
Title: Detection of a novel cytochrome P-450 1A2 polymorphism (F21L) in Chinese.
PubMed ID: 9884316
PubMed ID: 11295848
Title: Five novel natural allelic variants-951A->C, 1042G->A (D348N), 1156A->T (I386F), 1217G->A (C406Y) and 1291C->T (C431Y)-of the human CYP1A2 gene in a French Caucasian population.
PubMed ID: 11295848
PubMed ID: 14563787
Title: Six novel nonsynonymous CYP1A2 gene polymorphisms: catalytic activities of the naturally occurring variant enzymes.
PubMed ID: 14563787
PubMed ID: 15469410
Title: Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.
PubMed ID: 15469410
PubMed ID: 15770072
Title: Single nucleotide polymorphisms and haplotypes of CYP1A2 in a Japanese population.
PubMed ID: 15770072
DOI: 10.2133/dmpk.20.24
PubMed ID: 15643613
Title: Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus.
PubMed ID: 15643613
DOI: 10.1002/humu.20134
PubMed ID: 16522833
Title: Coffee, CYP1A2 genotype, and risk of myocardial infarction.
PubMed ID: 16522833
Sequence Information:
- Length: 516
- Mass: 58407
- Checksum: 8557AB02860C4806
- Sequence:
MALSQSVPFS ATELLLASAI FCLVFWVLKG LRPRVPKGLK SPPEPWGWPL LGHVLTLGKN PHLALSRMSQ RYGDVLQIRI GSTPVLVLSR LDTIRQALVR QGDDFKGRPD LYTSTLITDG QSLTFSTDSG PVWAARRRLA QNALNTFSIA SDPASSSSCY LEEHVSKEAK ALISRLQELM AGPGHFDPYN QVVVSVANVI GAMCFGQHFP ESSDEMLSLV KNTHEFVETA SSGNPLDFFP ILRYLPNPAL QRFKAFNQRF LWFLQKTVQE HYQDFDKNSV RDITGALFKH SKKGPRASGN LIPQEKIVNL VNDIFGAGFD TVTTAISWSL MYLVTKPEIQ RKIQKELDTV IGRERRPRLS DRPQLPYLEA FILETFRHSS FLPFTIPHST TRDTTLNGFY IPKKCCVFVN QWQVNHDPEL WEDPSEFRPE RFLTADGTAI NKPLSEKMML FGMGKRRCIG EVLAKWEIFL FLAILLQQLE FSVPPGVKVD LTPIYGLTMK HARCEHVQAR LRFSIN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.