Hpd | ENSMUSG00000029445 | NCBI 15445

Details for: Hpd

Gene ID: 15445

Symbol: Hpd

Ensembl ID: ENSMUSG00000029445

Description: 4-hydroxyphenylpyruvic acid dioxygenase

Associated with

Metabolism
(R-MMU-1430728)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Phenylalanine and tyrosine metabolism
(R-MMU-8963691)
Tyrosine catabolism
(R-MMU-8963684)
4-hydroxyphenylpyruvate dioxygenase activity
(GO:0003868)
Aromatic amino acid metabolic process
(GO:0009072)
Cytoplasm
(GO:0005737)
Dioxygenase activity
(GO:0051213)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Iron ion binding
(GO:0005506)
L-phenylalanine catabolic process
(GO:0006559)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
(GO:0016701)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Quercetin 2,3-dioxygenase activity
(GO:0008127)
Tyrosine catabolic process
(GO:0006572)

Other Information

Proteins

4-hydroxyphenylpyruvate dioxygenase

Genular Protein ID: 3328471591

Symbol: HPPD_MOUSE

Name: 4-hydroxyphenylpyruvate dioxygenase

UniProtKB Accession Codes:

P49429 P97322 Q3UEQ0 Q91WV9

Database IDs:

Citations:

PubMed ID: 7774914

Title: A nonsense mutation in the 4-hydroxyphenylpyruvic acid dioxygenase gene (Hpd) causes skipping of the constitutive exon and hypertyrosinemia in mouse strain III.

PubMed ID: 7774914

DOI: 10.1016/0888-7543(95)80122-3

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1709870

Title: Sequences of the mouse F protein alleles and identification of a T cell epitope.

PubMed ID: 1709870

DOI: 10.1002/eji.1830210521

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 393
Mass: 45054
Checksum: 70B42A4E4744744A
Sequence:

MTTYNNKGPK PERGRFLHFH SVTFWVGNAK QAASFYCNKM GFEPLAYRGL ETGSREVVSH 
VIKQGKIVFV LCSALNPWNK EMGDHLVKHG DGVKDIAFEV EDCDHIVQKA RERGAKIVRE 
PWVEQDKFGK VKFAVLQTYG DTTHTLVEKI NYTGRFLPGF EAPTYKDTLL PKLPRCNLEI 
IDHIVGNQPD QEMQSASEWY LKNLQFHRFW SVDDTQVHTE YSSLRSIVVT NYEESIKMPI 
NEPAPGRKKS QIQEYVDYNG GAGVQHIALK TEDIITAIRH LRERGTEFLA APSSYYKLLR 
ENLKSAKIQV KESMDVLEEL HILVDYDEKG YLLQIFTKPM QDRPTLFLEV IQRHNHQGFG 
AGNFNSLFKA FEEEQALRGN LTDLEPNGVR SGM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hpd

Associated with

Other Information

A nonsense mutation in the 4-hydroxyphenylpyruvic acid dioxygenase gene (Hpd) causes skipping of the constitutive exon and hypertyrosinemia in mouse strain III. PubMed ID: 7774914

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Sequences of the mouse F protein alleles and identification of a T cell epitope. PubMed ID: 1709870

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337