Genular: Defining Cellular Identity and Function

Details for: Hpgd

Gene ID: 15446

Symbol: Hpgd

Ensembl ID: ENSMUSG00000031613

Description: hydroxyprostaglandin dehydrogenase 15 (NAD)

Associated with

Biosynthesis of d-series resolvins
(R-MMU-9018676)
Biosynthesis of dha-derived spms
(R-MMU-9018677)
Biosynthesis of e-series 18(s)-resolvins
(R-MMU-9018896)
Biosynthesis of epa-derived spms
(R-MMU-9018679)
Biosynthesis of specialized proresolving mediators (spms)
(R-MMU-9018678)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Synthesis of lipoxins (lx)
(R-MMU-2142700)
15-hydroxyicosatetraenoate dehydrogenase activity
(GO:0047034)
15-hydroxyprostaglandin dehydrogenase (nad+) activity
(GO:0016404)
Basolateral plasma membrane
(GO:0016323)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Ductus arteriosus closure
(GO:0097070)
Extracellular space
(GO:0005615)
Fatty acid metabolic process
(GO:0006631)
Female pregnancy
(GO:0007565)
Identical protein binding
(GO:0042802)
Lipid metabolic process
(GO:0006629)
Nad+ binding
(GO:0070403)
Nad binding
(GO:0051287)
Negative regulation of cell cycle
(GO:0045786)
Nucleoplasm
(GO:0005654)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor
(GO:0016616)
Parturition
(GO:0007567)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of vascular associated smooth muscle cell proliferation
(GO:1904707)
Prostaglandin e receptor activity
(GO:0004957)
Prostaglandin metabolic process
(GO:0006693)
Regulation of prostaglandin catabolic process
(GO:1905828)
Response to ethanol
(GO:0045471)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)

Other Information

Proteins

15-hydroxyprostaglandin dehydrogenase [NAD(+)]

Genular Protein ID: 2218720641

Symbol: PGDH_MOUSE

Name: 15-hydroxyprostaglandin dehydrogenase [NAD(+)]

UniProtKB Accession Codes:

Q8VCC1 Q61106

Database IDs:

Citations:

PubMed ID: 8950170

Title: Cloning and expression of the cDNA for mouse NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.

PubMed ID: 8950170

DOI: 10.1016/s0167-4781(96)00123-6

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20448048

Title: A novel transporter of SLC22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules.

PubMed ID: 20448048

DOI: 10.1074/jbc.m109.084426

Sequence Information:

Length: 269
Mass: 29181
Checksum: 10E879A7E31A8E34
Sequence:

MHVNGKVALV TGAAQGIGKA FAEALLLHGA KVALVDWNLE AGVKCKAALD EQFEPQKTLF 
VQCDVADQKQ LRDTFRKVVD HFGRLDILVN NAGVNNEKNW EQTLQINLVS VISGTYLGLD 
YMSKQNGGEG GIIINMSSLA GLMPVAQQPV YCASKHGIIG FTRSAAMAAN LMKSGVRLNV 
ICPGFVDTPI LESIEKEENM GQYIEYKDQI KAMMKFYGVL HPSTIANGLI NLIEDDALNG 
AIMKITASKG IHFQDYDISP LLVKAPLTS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hpgd

Associated with

Other Information

Cloning and expression of the cDNA for mouse NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. PubMed ID: 8950170

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334