Genular: Defining Cellular Identity and Function

Details for: Lipc

Gene ID: 15450

Symbol: Lipc

Ensembl ID: ENSMUSG00000032207

Description: lipase, hepatic

Associated with

Assembly of active lpl and lipc lipase complexes
(R-MMU-8963889)
Chylomicron clearance
(R-MMU-8964026)
Plasma lipoprotein assembly, remodeling, and clearance
(R-MMU-174824)
Plasma lipoprotein clearance
(R-MMU-8964043)
Plasma lipoprotein remodeling
(R-MMU-8963899)
Transport of small molecules
(R-MMU-382551)
1-acyl-2-lysophosphatidylserine acylhydrolase activity
(GO:0052740)
Acetylesterase activity
(GO:0008126)
Acylglycerol lipase activity
(GO:0047372)
Acyltransferase activity
(GO:0016746)
Apolipoprotein binding
(GO:0034185)
Carboxylic ester hydrolase activity
(GO:0052689)
Cell surface
(GO:0009986)
Cholesterol homeostasis
(GO:0042632)
Cholesterol metabolic process
(GO:0008203)
Cholesterol transport
(GO:0030301)
Chylomicron binding
(GO:0035478)
Chylomicron remnant clearance
(GO:0034382)
Chylomicron remodeling
(GO:0034371)
Early endosome
(GO:0005769)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fatty acid biosynthetic process
(GO:0006633)
Fatty acid metabolic process
(GO:0006631)
Glycerophospholipid catabolic process
(GO:0046475)
Heparan sulfate proteoglycan binding
(GO:0043395)
Heparan sulfate proteoglycan biosynthetic process
(GO:0015012)
Heparin binding
(GO:0008201)
High-density lipoprotein particle
(GO:0034364)
High-density lipoprotein particle remodeling
(GO:0034375)
Hydrolase activity
(GO:0016787)
Identical protein binding
(GO:0042802)
Late endosome
(GO:0005770)
Lipase activity
(GO:0016298)
Lipid binding
(GO:0008289)
Lipid catabolic process
(GO:0016042)
Lipid metabolic process
(GO:0006629)
Lipoprotein lipase activity
(GO:0004465)
Low-density lipoprotein particle binding
(GO:0030169)
Low-density lipoprotein particle clearance
(GO:0034383)
Low-density lipoprotein particle remodeling
(GO:0034374)
Lysophospholipase activity
(GO:0004622)
Microvillus
(GO:0005902)
Neutral lipid catabolic process
(GO:0046461)
Phosphatidic acid metabolic process
(GO:0046473)
Phosphatidylcholine metabolic process
(GO:0046470)
Phosphatidylethanolamine metabolic process
(GO:0046337)
Phosphatidyl phospholipase b activity
(GO:0102545)
Phosphatidylserine 1-acylhydrolase activity
(GO:0052739)
Phosphatidylserine metabolic process
(GO:0006658)
Phospholipase a1 activity
(GO:0008970)
Protein binding
(GO:0005515)
Regulation of plasma lipoprotein particle levels
(GO:0097006)
Triglyceride catabolic process
(GO:0019433)
Triglyceride homeostasis
(GO:0070328)
Triglyceride lipase activity
(GO:0004806)
Triglyceride metabolic process
(GO:0006641)
Very-low-density lipoprotein particle remodeling
(GO:0034372)

Other Information

Proteins

Hepatic triacylglycerol lipase
Q3TYU0_MOUSE

Genular Protein ID: 2327806409

Symbol: LIPC_MOUSE

Name: Hepatic triacylglycerol lipase

UniProtKB Accession Codes:

P27656 Q8VC44

Database IDs:

Citations:

PubMed ID: 2025643

Title: Molecular cloning of mouse hepatic triacylglycerol lipase: gene expression in combined lipase-deficient (cld/cld) mice.

PubMed ID: 2025643

DOI: 10.1016/0167-4781(91)90078-z

PubMed ID: 1840530

Title: Characterization of cDNA encoding the mouse hepatic triglyceride lipase and expression by in vitro translation.

PubMed ID: 1840530

DOI: 10.1016/0014-5793(91)80910-u

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 510
Mass: 57389
Checksum: E30222652D782A05
Sequence:

MGNPLQISIF LVFCIFIQSS ACGQGVGTEP FGRSLGATEA SKPLKKPETR FLLFQDENDR 
LGCRLRPQHP ETLQECGFNS SQPLIMIIHG WSVDGLLENW IWKIVSALKS RQSQPVNVGL 
VDWISLAYQH YTIAVQNTRI VGQDVAALLL WLEESAKFSR SKVHLIGYSL GAHVSGFAGS 
SMDGKNKIGR ITGLDPAGPM FEGTSPNERL SPDDANFVDA IHTFTREHMG LSVGIKQPIA 
HYDFYPNGGS FQPGCHFLEL YKHIAEHGLN AITQTIKCAH ERSVHLFIDS LQHSDLQSIG 
FQCSDMGSFS QGLCLSCKKG RCNTLGYDIR KDRSGKSKRL FLITRAQSPF KVYHYQFKIQ 
FINQIEKPVE PTFTMSLLGT KEEIKRIPIT LGEGITSNKT YSFLITLDKD IGELILLKFK 
WENSAVWANV WNTVQTIMLW GIEPHHSGLI LKTIWVKAGE TQQRMTFCPE NLDDLQLHPS 
QEKVFVNCEV KSKRLTESKE QMSQETHAKK

Genular Protein ID: 1843684270

Symbol: Q3TYU0_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TYU0

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 425
Mass: 48009
Checksum: 095637E1F3DB2B86
Sequence:

MIIHGWSVDG LLENWIWKIV SALKSRQSQP VNVGLVDWIS LAYQHYTIAV QNTRIVGQDV 
AALLLWLEES AKFSRSKVHL IGYSLGAHVS GFAGSSMDGK NKIGRITGLD PAGPMFEGTS 
PNERLSPDDA NFVDAIHTFT REHMGLSVGI KQPIAHYDFY PNGGSFQPGC HFLELYKHIA 
EHGLNAITQT IKCAHERSVH LFIDSLQHSD LQSIGFQCSD MGSFSQGLCL SCKKGRCNTL 
GYDIRKDRSG KSKRLFLITR AQSPFKVYHY QFKIQFINQI EKPVEPTFTM SLLGTKEEIK 
RIPITLGEGI TSNKTYSFLI TLDKDIGELI LLKFKWENSA VWANVWNTVQ TIMLWGIEPH 
HSGLILKTIW VKAGETQQRM TFCPENLDDL QLHPSQEKVF VNCEVKSKRL TESKEQMSQE 
THAKK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Lipc

Associated with

Other Information

Molecular cloning of mouse hepatic triacylglycerol lipase: gene expression in combined lipase-deficient (cld/cld) mice. PubMed ID: 2025643

Characterization of cDNA encoding the mouse hepatic triglyceride lipase and expression by in vitro translation. PubMed ID: 1840530

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303