Hprt1 | ENSMUSG00000025630 | NCBI 15452

Details for: Hprt1

Gene ID: 15452

Symbol: Hprt1

Ensembl ID: ENSMUSG00000025630

Description: hypoxanthine phosphoribosyltransferase 1

Associated with

Azathioprine adme
(R-MMU-9748787)
Drug adme
(R-MMU-9748784)
Metabolism
(R-MMU-1430728)
Metabolism of nucleotides
(R-MMU-15869)
Nucleotide salvage
(R-MMU-8956321)
Purine salvage
(R-MMU-74217)
Adenine metabolic process
(GO:0046083)
Amp salvage
(GO:0044209)
Central nervous system neuron development
(GO:0021954)
Cerebral cortex neuron differentiation
(GO:0021895)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendrite morphogenesis
(GO:0048813)
Dopamine metabolic process
(GO:0042417)
Dopaminergic neuron differentiation
(GO:0071542)
Glycosyltransferase activity
(GO:0016757)
Gmp catabolic process
(GO:0046038)
Gmp salvage
(GO:0032263)
Grooming behavior
(GO:0007625)
Guanine phosphoribosyltransferase activity
(GO:0052657)
Guanine salvage
(GO:0006178)
Hypoxanthine metabolic process
(GO:0046100)
Hypoxanthine phosphoribosyltransferase activity
(GO:0004422)
Hypoxanthine salvage
(GO:0043103)
Identical protein binding
(GO:0042802)
Imp metabolic process
(GO:0046040)
Imp salvage
(GO:0032264)
Locomotory behavior
(GO:0007626)
Lymphocyte proliferation
(GO:0046651)
Magnesium ion binding
(GO:0000287)
Metal ion binding
(GO:0046872)
Nucleotide binding
(GO:0000166)
Positive regulation of dopamine metabolic process
(GO:0045964)
Protein homotetramerization
(GO:0051289)
Purine nucleotide biosynthetic process
(GO:0006164)
Purine ribonucleoside salvage
(GO:0006166)
Response to amphetamine
(GO:0001975)
Striatum development
(GO:0021756)
T cell mediated cytotoxicity
(GO:0001913)
Transferase activity
(GO:0016740)

Other Information

Proteins

Hypoxanthine-guanine phosphoribosyltransferase

Genular Protein ID: 1786154800

Symbol: HPRT_MOUSE

Name: Hypoxanthine-guanine phosphoribosyltransferase

UniProtKB Accession Codes:

P00493 Q545Y2

Database IDs:

Citations:

PubMed ID: 6294614

Title: Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants.

PubMed ID: 6294614

DOI: 10.1093/nar/10.21.6763

PubMed ID: 6326107

Title: Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.

PubMed ID: 6326107

DOI: 10.1073/pnas.81.7.2147

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 218
Mass: 24570
Checksum: 925CC0D4A6626E05
Sequence:

MPTRSPSVVI SDDEPGYDLD LFCIPNHYAE DLEKVFIPHG LIMDRTERLA RDVMKEMGGH 
HIVALCVLKG GYKFFADLLD YIKALNRNSD RSIPMTVDFI RLKSYCNDQS TGDIKVIGGD 
DLSTLTGKNV LIVEDIIDTG KTMQTLLSLV KQYSPKMVKV ASLLVKRTSR SVGYRPDFVG 
FEIPDKFVVG YALDYNEYFR DLNHVCVISE TGKAKYKA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hprt1

Associated with

Other Information

Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants. PubMed ID: 6294614

Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene. PubMed ID: 6326107

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079