Genular: Defining Cellular Identity and Function

Details for: Hras

Gene ID: 15461

Symbol: Hras

Ensembl ID: ENSMUSG00000025499

Description: Harvey rat sarcoma virus oncogene

Associated with

Activation of ras in b cells
(R-MMU-1169092)
Adaptive immune system
(R-MMU-1280218)
Axon guidance
(R-MMU-422475)
C-type lectin receptors (clrs)
(R-MMU-5621481)
Cd209 (dc-sign) signaling
(R-MMU-5621575)
Cell surface interactions at the vascular wall
(R-MMU-202733)
Cytokine signaling in immune system
(R-MMU-1280215)
Dap12 interactions
(R-MMU-2172127)
Dap12 signaling
(R-MMU-2424491)
Developmental biology
(R-MMU-1266738)
Downstream signaling events of b cell receptor (bcr)
(R-MMU-1168372)
Downstream signaling of activated fgfr1
(R-MMU-5654687)
Downstream signaling of activated fgfr2
(R-MMU-5654696)
Downstream signaling of activated fgfr3
(R-MMU-5654708)
Downstream signaling of activated fgfr4
(R-MMU-5654716)
Downstream signal transduction
(R-MMU-186763)
Egfr transactivation by gastrin
(R-MMU-2179392)
Eph-ephrin signaling
(R-MMU-2682334)
Ephb-mediated forward signaling
(R-MMU-3928662)
Esr-mediated signaling
(R-MMU-8939211)
Estrogen-stimulated signaling through prkcz
(R-MMU-9634635)
Extra-nuclear estrogen signaling
(R-MMU-9009391)
Fc epsilon receptor (fceri) signaling
(R-MMU-2454202)
Fceri mediated mapk activation
(R-MMU-2871796)
Flt3 signaling
(R-MMU-9607240)
Frs-mediated fgfr1 signaling
(R-MMU-5654693)
Frs-mediated fgfr2 signaling
(R-MMU-5654700)
Frs-mediated fgfr3 signaling
(R-MMU-5654706)
Frs-mediated fgfr4 signaling
(R-MMU-5654712)
G alpha (q) signalling events
(R-MMU-416476)
Gastrin-creb signalling pathway via pkc and mapk
(R-MMU-881907)
Gpcr downstream signalling
(R-MMU-388396)
Grb2 events in egfr signaling
(R-MMU-179812)
Grb2 events in erbb2 signaling
(R-MMU-1963640)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Map2k and mapk activation
(R-MMU-5674135)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Met activates ras signaling
(R-MMU-8851805)
Ncam signaling for neurite out-growth
(R-MMU-375165)
Negative regulation of mapk pathway
(R-MMU-5675221)
Nervous system development
(R-MMU-9675108)
P38mapk events
(R-MMU-171007)
Ptk6 regulates rho gtpases, ras gtpase and map kinases
(R-MMU-8849471)
Raf/map kinase cascade
(R-MMU-5673001)
Raf activation
(R-MMU-5673000)
Ras processing
(R-MMU-9648002)
Regulation of ras by gaps
(R-MMU-5658442)
Shc-mediated cascade:fgfr1
(R-MMU-5654688)
Shc-mediated cascade:fgfr2
(R-MMU-5654699)
Shc-mediated cascade:fgfr3
(R-MMU-5654704)
Shc-mediated cascade:fgfr4
(R-MMU-5654719)
Shc1 events in egfr signaling
(R-MMU-180336)
Shc1 events in erbb4 signaling
(R-MMU-1250347)
Signaling by egfr
(R-MMU-177929)
Signaling by erbb2
(R-MMU-1227986)
Signaling by erbb4
(R-MMU-1236394)
Signaling by fgfr
(R-MMU-190236)
Signaling by fgfr1
(R-MMU-5654736)
Signaling by fgfr2
(R-MMU-5654738)
Signaling by fgfr3
(R-MMU-5654741)
Signaling by fgfr4
(R-MMU-5654743)
Signaling by gpcr
(R-MMU-372790)
Signaling by met
(R-MMU-6806834)
Signaling by non-receptor tyrosine kinases
(R-MMU-9006927)
Signaling by ntrk1 (trka)
(R-MMU-187037)
Signaling by ntrks
(R-MMU-166520)
Signaling by nuclear receptors
(R-MMU-9006931)
Signaling by pdgf
(R-MMU-186797)
Signaling by ptk6
(R-MMU-8848021)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by scf-kit
(R-MMU-1433557)
Signaling by the b cell receptor (bcr)
(R-MMU-983705)
Signaling by vegf
(R-MMU-194138)
Signalling to erks
(R-MMU-187687)
Signalling to ras
(R-MMU-167044)
Tie2 signaling
(R-MMU-210993)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Vegfr2 mediated cell proliferation
(R-MMU-5218921)
Endocytosis
(GO:0006897)
Gdp binding
(GO:0019003)
G protein activity
(GO:0003925)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Hydrolase activity
(GO:0016787)
Nucleotide binding
(GO:0000166)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein-containing complex binding
(GO:0044877)
Protein-membrane adaptor activity
(GO:0043495)
Protein binding
(GO:0005515)
Ras protein signal transduction
(GO:0007265)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Signal transduction
(GO:0007165)
Small gtpase-mediated signal transduction
(GO:0007264)

Other Information

Proteins

GTPase HRas

Genular Protein ID: 1179002663

Symbol: RASH_MOUSE

Name: GTPase HRas

UniProtKB Accession Codes:

Q61411 F7BIB2 Q6P716 Q80WD2 Q811B9

Database IDs:

Citations:

PubMed ID: 8922043

Title: Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice.

PubMed ID: 8922043

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7526162

Title: Spontaneous mutation at codon 61 of the Ha-ras gene in the nascent liver of B6C3F1, C3H/He and C57BL/6 mice.

PubMed ID: 7526162

DOI: 10.1016/0027-5107(94)90067-1

PubMed ID: 14500341

Title: Alternative splicing of the human proto-oncogene c-H-ras renders a new Ras family protein that trafficks to cytoplasm and nucleus.

PubMed ID: 14500341

PubMed ID: 1347942

Title: An interaction between p21ras and heat shock protein hsp60, a chaperonin.

PubMed ID: 1347942

DOI: 10.1073/pnas.89.6.2012

PubMed ID: 10869344

Title: A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras.

PubMed ID: 10869344

DOI: 10.1074/jbc.m002241200

PubMed ID: 16580637

Title: Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.

PubMed ID: 16580637

DOI: 10.1016/j.bbrc.2006.03.063

PubMed ID: 19906996

Title: Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma.

PubMed ID: 19906996

DOI: 10.1073/pnas.0905506106

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 189
Mass: 21298
Checksum: EE6DC2D933E2856A
Sequence:

MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG 
QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHQYREQI KRVKDSDDVP MVLVGNKCDL 
AARTVESRQA QDLARSYGIP YIETSAKTRQ GVEDAFYTLV REIRQHKLRK LNPPDESGPG 
CMSCKCVLS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hras

Associated with

Other Information

Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice. PubMed ID: 8922043

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Spontaneous mutation at codon 61 of the Ha-ras gene in the nascent liver of B6C3F1, C3H/He and C57BL/6 mice. PubMed ID: 7526162

Alternative splicing of the human proto-oncogene c-H-ras renders a new Ras family protein that trafficks to cytoplasm and nucleus. PubMed ID: 14500341

An interaction between p21ras and heat shock protein hsp60, a chaperonin. PubMed ID: 1347942

A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras. PubMed ID: 10869344

Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis. PubMed ID: 16580637

Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma. PubMed ID: 19906996

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079