Genular: Defining Cellular Identity and Function

Details for: Hrh1

Gene ID: 15465

Symbol: Hrh1

Ensembl ID: ENSMUSG00000053004

Description: histamine receptor H1

Associated with

Amine ligand-binding receptors
(R-MMU-375280)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Histamine receptors
(R-MMU-390650)
Signaling by gpcr
(R-MMU-372790)
Calcium ion import
(GO:0070509)
Calcium ion transmembrane transport
(GO:0070588)
Calcium ion transmembrane transporter activity
(GO:0015085)
Cellular response to histamine
(GO:0071420)
Chemical synaptic transmission
(GO:0007268)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
(GO:0007187)
G protein-coupled serotonin receptor activity
(GO:0004993)
Histamine binding
(GO:0051381)
Histamine receptor activity
(GO:0004969)
Manganese ion transmembrane transport
(GO:0071421)
Membrane
(GO:0016020)
Memory
(GO:0007613)
Negative regulation of steroid biosynthetic process
(GO:0010894)
Neurotransmitter receptor activity
(GO:0030594)
Plasma membrane
(GO:0005886)
Positive regulation of nitric oxide biosynthetic process
(GO:0045429)
Positive regulation of vasoconstriction
(GO:0045907)
Regulation of synaptic plasticity
(GO:0048167)
Regulation of vascular permeability
(GO:0043114)
Rhythmic process
(GO:0048511)
Signal transduction
(GO:0007165)
Visual learning
(GO:0008542)

Other Information

Proteins

Histamine H1 receptor

Genular Protein ID: 1870155537

Symbol: HRH1_MOUSE

Name: Histamine H1 receptor

UniProtKB Accession Codes:

P70174 Q91V75 Q91XN0 Q91XN1 Q91XN2 Q91XN3

Database IDs:

Citations:

PubMed ID: 8812432

Title: Characteristics of the mouse genomic histamine H1 receptor gene.

PubMed ID: 8812432

DOI: 10.1006/geno.1996.0441

PubMed ID: 12142541

Title: Identification of Bphs, an autoimmune disease locus, as histamine receptor H1.

PubMed ID: 12142541

DOI: 10.1126/science.1072810

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 8917588

Title: Impaired locomotor activity and exploratory behavior in mice lacking histamine H1 receptors.

PubMed ID: 8917588

DOI: 10.1073/pnas.93.23.13316

PubMed ID: 12595443

Title: Analysis of the role of Bphs/Hrh1 in the genetic control of responsiveness to pertussis toxin.

PubMed ID: 12595443

DOI: 10.1128/iai.71.3.1281-1287.2003

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 488
Mass: 55682
Checksum: 82612DF712998B41
Sequence:

MSLPNTSSAS EDKMCEGNRT AMASPQLLPL VVVLSSISLV TVGLNLLVLY AVRSERKLHT 
VGNLYIVSLS VADLIVGAVV MPMNILYLIM TKWSLGRPLC LFWLSMDYVA STASIFSVFI 
LCIDRYRSVQ QPLRYLRYRT KTRASATILG AWFLSFLWVI PILGWHHFTP LAPELREDKC 
ETDFYNVTWF KIMTAIINFY LPTLLMLWFY VKIYKAVRRH CQHRQLTNGS LPTFLEIKLR 
SEDAKEGAKK PGKESPWGVQ KRPSRDPTGG LDQKSTSEDP KVTSPTVFSQ EGERETVTRP 
CFRLDVMQTQ PVPEGDARGS KANDQTLSQP KMDEQSLSTC RRISETSEDQ TLVDRQSFSR 
TTDSDTSIEP GLGKVKARSR SNSGLDYIKV TWKRLRSHSR QYVSGLHLNR ERKAAKQLGC 
IMAAFILCWI PYFIFFMVIA FCNSCCSEPV HMFTIWLGYI NSTLNPLIYP LCNENFKKTF 
KKILHIRS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hrh1

Associated with

Other Information

Characteristics of the mouse genomic histamine H1 receptor gene. PubMed ID: 8812432

Identification of Bphs, an autoimmune disease locus, as histamine receptor H1. PubMed ID: 12142541

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Impaired locomotor activity and exploratory behavior in mice lacking histamine H1 receptors. PubMed ID: 8917588

Analysis of the role of Bphs/Hrh1 in the genetic control of responsiveness to pertussis toxin. PubMed ID: 12595443