Details for: CYP2A6

Gene ID: 1548

Symbol: CYP2A6

Ensembl ID: ENSG00000255974

Description: cytochrome P450 family 2 subfamily A member 6

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 16.4764
    Cell Significance Index: 243.1900
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 12.3164
    Cell Significance Index: 32.4900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 4.7958
    Cell Significance Index: 80.7900
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.6904
    Cell Significance Index: 40.2500
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 1.2891
    Cell Significance Index: 4.8600
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.6181
    Cell Significance Index: 4.8800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.5541
    Cell Significance Index: 8.8900
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 0.5506
    Cell Significance Index: 1.4800
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 0.5231
    Cell Significance Index: 1.8200
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.5079
    Cell Significance Index: 2.9300
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.4314
    Cell Significance Index: 4.4500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.3625
    Cell Significance Index: 9.3200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 0.3117
    Cell Significance Index: -1.2300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.3038
    Cell Significance Index: 5.1100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.2430
    Cell Significance Index: 3.4800
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.0747
    Cell Significance Index: 0.7100
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.0584
    Cell Significance Index: 0.3600
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.0578
    Cell Significance Index: 0.5700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0175
    Cell Significance Index: 0.4700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0133
    Cell Significance Index: 0.9900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0052
    Cell Significance Index: 0.0700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0041
    Cell Significance Index: 0.8200
  • Cell Name: inflammatory macrophage (CL0000863)
    Fold Change: 0.0039
    Cell Significance Index: 0.0300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0031
    Cell Significance Index: 0.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0027
    Cell Significance Index: 0.7900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.0023
    Cell Significance Index: 0.0300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0023
    Cell Significance Index: 0.3100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0014
    Cell Significance Index: 0.2800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0002
    Cell Significance Index: 0.2500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0001
    Cell Significance Index: 0.0500
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0002
    Cell Significance Index: -0.4400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0002
    Cell Significance Index: -0.3600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0005
    Cell Significance Index: -0.9300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0006
    Cell Significance Index: -0.0200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0010
    Cell Significance Index: -0.7900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0013
    Cell Significance Index: -0.9900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0018
    Cell Significance Index: -1.0100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0021
    Cell Significance Index: -1.3400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0024
    Cell Significance Index: -0.2900
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0025
    Cell Significance Index: -0.0500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0028
    Cell Significance Index: -1.2600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0047
    Cell Significance Index: -0.8000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0052
    Cell Significance Index: -0.7600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0055
    Cell Significance Index: -0.6400
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: -0.0058
    Cell Significance Index: -0.0600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0070
    Cell Significance Index: -0.3700
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: -0.0076
    Cell Significance Index: -0.0700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0078
    Cell Significance Index: -0.3400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0098
    Cell Significance Index: -0.6600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0098
    Cell Significance Index: -1.0200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0106
    Cell Significance Index: -0.8100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0107
    Cell Significance Index: -1.3800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0127
    Cell Significance Index: -0.4500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0134
    Cell Significance Index: -0.4400
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.0157
    Cell Significance Index: -0.2200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0171
    Cell Significance Index: -0.4500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0181
    Cell Significance Index: -0.5800
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0193
    Cell Significance Index: -0.2300
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0217
    Cell Significance Index: -0.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0219
    Cell Significance Index: -1.2300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0228
    Cell Significance Index: -1.0100
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: -0.0242
    Cell Significance Index: -0.2000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0243
    Cell Significance Index: -0.6100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0244
    Cell Significance Index: -1.1500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0251
    Cell Significance Index: -0.9500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0267
    Cell Significance Index: -0.7700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0274
    Cell Significance Index: -0.6000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0282
    Cell Significance Index: -0.6000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0295
    Cell Significance Index: -0.5100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0301
    Cell Significance Index: -0.6500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0307
    Cell Significance Index: -0.9700
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: -0.0323
    Cell Significance Index: -0.2800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0328
    Cell Significance Index: -0.7100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0340
    Cell Significance Index: -0.9100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0343
    Cell Significance Index: -0.9800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0344
    Cell Significance Index: -0.4700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0354
    Cell Significance Index: -0.7000
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0355
    Cell Significance Index: -0.7400
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: -0.0360
    Cell Significance Index: -0.3100
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.0361
    Cell Significance Index: -0.4200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0364
    Cell Significance Index: -0.7300
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0381
    Cell Significance Index: -0.7500
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0384
    Cell Significance Index: -0.5600
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0389
    Cell Significance Index: -0.9700
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0391
    Cell Significance Index: -0.7800
  • Cell Name: mature B cell (CL0000785)
    Fold Change: -0.0392
    Cell Significance Index: -0.2600
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.0401
    Cell Significance Index: -0.6600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0403
    Cell Significance Index: -1.0300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0411
    Cell Significance Index: -1.1200
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.0412
    Cell Significance Index: -0.5300
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0421
    Cell Significance Index: -0.5500
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0428
    Cell Significance Index: -0.6500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0438
    Cell Significance Index: -1.0500
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0450
    Cell Significance Index: -0.5000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0455
    Cell Significance Index: -1.1600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0459
    Cell Significance Index: -0.5000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0463
    Cell Significance Index: -0.7800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0465
    Cell Significance Index: -0.5800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0472
    Cell Significance Index: -1.2600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CYP2A6 is a non-heme, iron-containing monooxygenase that belongs to the cytochrome P450 superfamily. It is a dimeric enzyme composed of two alpha subunits, each with a heme group that binds to oxygen. CYP2A6 has a high degree of substrate specificity, with a preference for hydroxylation reactions. The enzyme is also capable of catalyzing epoxidation and oxidation reactions, albeit to a lesser extent. CYP2A6 has been shown to be highly inducible, with increased expression in response to various stimuli, including cigarette smoke and certain drugs. **Pathways and Functions:** CYP2A6 is involved in the metabolism of a wide range of compounds, including: 1. **Arachidonic acid epoxygenase activity**: CYP2A6 catalyzes the epoxidation of arachidonic acid, leading to the production of epoxyeicosatrienoic acids (EETs), which have been implicated in various physiological and pathological processes. 2. **Biological oxidations**: CYP2A6 participates in the oxidation of various substrates, including steroids, xenobiotics, and endogenous compounds. 3. **Coumarin 7-hydroxylase activity**: CYP2A6 is involved in the hydroxylation of coumarin, a compound found in certain plant-based foods. 4. **Metabolism**: CYP2A6 plays a crucial role in the metabolism of various endogenous compounds, including steroids and eicosanoids. **Clinical Significance:** CYP2A6 has significant clinical implications, particularly in the context of drug metabolism and immune function. Variations in the CYP2A6 gene have been associated with altered enzyme activity, leading to differences in the metabolism of various drugs, including: 1. **Cigarette smoke**: CYP2A6 is highly inducible by cigarette smoke, leading to increased expression and activity of the enzyme. 2. **Antidepressants**: CYP2A6 is involved in the metabolism of certain antidepressants, including selective serotonin reuptake inhibitors (SSRIs), which can be affected by variations in the CYP2A6 gene. 3. **Infectious diseases**: CYP2A6 has been implicated in the metabolism of certain antibiotics and anti-inflammatory compounds, which can be affected by variations in the CYP2A6 gene. In addition to its role in drug metabolism, CYP2A6 has also been implicated in immune function, particularly in the context of: 1. **Immune cell function**: CYP2A6 is expressed in various immune cells, including dendritic cells and T lymphocytes, and plays a role in the regulation of immune responses. 2. **Autoimmune diseases**: Variations in the CYP2A6 gene have been associated with an increased risk of autoimmune diseases, including rheumatoid arthritis and lupus. In conclusion, CYP2A6 is a complex enzyme with a wide range of substrates and functions, including metabolism, epoxidation, and hydroxylation reactions. Its clinical significance is evident in its role in drug metabolism and immune function, and variations in the CYP2A6 gene can have significant implications for patient outcomes. Further research is needed to fully elucidate the role of CYP2A6 in human health and disease.

Genular Protein ID: 3809079103

Symbol: CP2A6_HUMAN

Name: Cytochrome P450 2A6

UniProtKB Accession Codes:

P11509 A7YAE5 B2R7F6 P00190 P10890 Q16803 Q4VAT9 Q4VAU0 Q4VAU1 Q9H1Z7 Q9UCU0 Q9UK48

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 10 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 90 DrugCentral 1 EC 1 EMBL 16 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 11 PIR 2 PRINTS 3 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 Rhea 3 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 2726448

Title: Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity.

PubMed ID: 2726448

DOI: 10.1093/nar/17.8.2907

PubMed ID: 2748347

Title: cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3).

PubMed ID: 2748347

DOI: 10.1093/nar/17.12.4888

PubMed ID: 2322567

Title: The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes.

PubMed ID: 2322567

DOI: 10.1021/bi00457a031

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1889415

Title: Isolation and characterization of a cytochrome P450 of the IIA subfamily from human liver microsomes.

PubMed ID: 1889415

DOI: 10.1111/j.1432-1033.1991.tb16212.x

PubMed ID: 1944238

Title: Purification and characterization of human liver microsomal cytochrome P-450 2A6.

PubMed ID: 1944238

PubMed ID: 11278503

Title: CYP2A6*6, a novel polymorphism in cytochrome p450 2A6, has a single amino acid substitution (R128Q) that inactivates enzymatic activity.

PubMed ID: 11278503

DOI: 10.1074/jbc.m009432200

PubMed ID: 3856261

Title: Isolation and sequence of a human cytochrome P-450 cDNA clone.

PubMed ID: 3856261

DOI: 10.1073/pnas.82.4.983

PubMed ID: 11695850

Title: Roles of cytochrome P450 3A enzymes in the 2-hydroxylation of 1,4-cineole, a monoterpene cyclic ether, by rat and human liver microsomes.

PubMed ID: 11695850

DOI: 10.1080/00498250110065595

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 16086027

Title: Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen.

PubMed ID: 16086027

DOI: 10.1038/nsmb971

PubMed ID: 17125252

Title: Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization.

PubMed ID: 17125252

DOI: 10.1021/jm060519r

PubMed ID: 18779312

Title: Key residues controlling phenacetin metabolism by human cytochrome P450 2A enzymes.

PubMed ID: 18779312

DOI: 10.1124/dmd.108.023770

PubMed ID: 9409631

Title: A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin.

PubMed ID: 9409631

DOI: 10.1016/s0278-6915(97)00066-5

PubMed ID: 10544257

Title: Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism.

PubMed ID: 10544257

DOI: 10.1016/s0014-5793(99)01364-2

PubMed ID: 11237731

Title: A novel single nucleotide polymorphism altering stability and activity of CYP2a6.

PubMed ID: 11237731

DOI: 10.1006/bbrc.2001.4422

PubMed ID: 15618701

Title: Twenty one novel single nucleotide polymorphisms (SNPs) of the CYP2A6 gene in Japanese and Caucasians.

PubMed ID: 15618701

DOI: 10.2133/dmpk.17.482

PubMed ID: 12721789

Title: Catalog of 680 variations among eight cytochrome p450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population.

PubMed ID: 12721789

DOI: 10.1007/s10038-003-0021-7

PubMed ID: 15469410

Title: Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.

PubMed ID: 15469410

DOI: 10.1517/14622416.5.7.895

PubMed ID: 18360915

Title: Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent.

PubMed ID: 18360915

DOI: 10.1002/humu.20698

PubMed ID: 18216723

Title: A novel CYP2A6 allele, CYP2A6*23, impairs enzyme function in vitro and in vivo and decreases smoking in a population of Black-African descent.

PubMed ID: 18216723

DOI: 10.1097/fpc.0b013e3282f3606e

Sequence Information:

  • Length: 494
  • Mass: 56517
  • Checksum: 562D697ADE558B04
  • Sequence:
    • MLASGMLLVA LLVCLTVMVL MSVWQQRKSK GKLPPGPTPL PFIGNYLQLN TEQMYNSLMK 
ISERYGPVFT IHLGPRRVVV LCGHDAVREA LVDQAEEFSG RGEQATFDWV FKGYGVVFSN 
GERAKQLRRF SIATLRDFGV GKRGIEERIQ EEAGFLIDAL RGTGGANIDP TFFLSRTVSN 
VISSIVFGDR FDYKDKEFLS LLRMMLGIFQ FTSTSTGQLY EMFSSVMKHL PGPQQQAFQL 
LQGLEDFIAK KVEHNQRTLD PNSPRDFIDS FLIRMQEEEK NPNTEFYLKN LVMTTLNLFI 
GGTETVSTTL RYGFLLLMKH PEVEAKVHEE IDRVIGKNRQ PKFEDRAKMP YMEAVIHEIQ 
RFGDVIPMSL ARRVKKDTKF RDFFLPKGTE VYPMLGSVLR DPSFFSNPQD FNPQHFLNEK 
GQFKKSDAFV PFSIGKRNCF GEGLARMELF LFFTTVMQNF RLKSSQSPKD IDVSPKHVGF 
ATIPRNYTMS FLPR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.