Genular: Defining Cellular Identity and Function

Details for: Hsd17b1

Gene ID: 15485

Symbol: Hsd17b1

Ensembl ID: ENSMUSG00000019301

Description: hydroxysteroid (17-beta) dehydrogenase 1

Associated with

Estrogen biosynthesis
(R-MMU-193144)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of steroid hormones
(R-MMU-196071)
Metabolism of steroids
(R-MMU-8957322)
17-beta-hydroxysteroid dehydrogenase (nadp+) activity
(GO:0072582)
Adipose tissue development
(GO:0060612)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dihydrotestosterone 17-beta-dehydrogenase activity
(GO:0035410)
Estradiol 17-beta-dehydrogenase [nad(p)] activity
(GO:0004303)
Estradiol binding
(GO:1903924)
Estrogen biosynthetic process
(GO:0006703)
Gene expression
(GO:0010467)
Lipid metabolic process
(GO:0006629)
Lysosome organization
(GO:0007040)
Nadp+ binding
(GO:0070401)
Nadp binding
(GO:0050661)
Oxidoreductase activity
(GO:0016491)
Protein homodimerization activity
(GO:0042803)
Skeletal muscle tissue development
(GO:0007519)
Small molecule binding
(GO:0036094)
Steroid binding
(GO:0005496)
Steroid biosynthetic process
(GO:0006694)
Testosterone biosynthetic process
(GO:0061370)
Testosterone dehydrogenase (nad+) activity
(GO:0047035)
Testosterone dehydrogenase [nad(p)] activity
(GO:0030283)

Other Information

Proteins

DHB1_MOUSE

Genular Protein ID: 4288880415

Symbol: DHB1_MOUSE

Name: N/A

UniProtKB Accession Codes:

P51656

Database IDs:

Citations:

PubMed ID: 8612620

Title: Molecular cloning of mouse 17 beta-hydroxysteroid dehydrogenase type 1 and characterization of enzyme activity.

PubMed ID: 8612620

DOI: 10.1111/j.1432-1033.1996.00482.x

PubMed ID: 9658408

Title: Expression cloning of a novel estrogenic mouse 17 beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase (m17HSD7), previously described as a prolactin receptor-associated protein (PRAP) in rat.

PubMed ID: 9658408

DOI: 10.1210/mend.12.7.0134

Sequence Information:

Length: 344
Mass: 36785
Checksum: 0335C473F453C14A
Sequence:

MDPTVVLITG CSSGIGMHLA VRLASDRSQS FKVYATLRDL KAQGPLLEAA RTQGCPPGSL 
EILELDVRDS KSVAAAQACV TEGRVDVLVC NAGRGLFGPL EAHELNAVGA VLDVNVLGTI 
RMLQAFLPDM KRRHSGRVLV TASVGGLMGL PFHEVYCASK FALEGLCESL AILLPLFGVH 
VSLIECGAVH TAFYEKLVGG PGGALERADA QTRHLFAHYL RGYEQALSEA QDPEEVTELF 
LTAMRAPQPA LRYFSTNRFL PLARMRTEDP SGSSYVAAMH QEAFSNLQTQ ENAKAGAQVP 
GVSDTASSAL ICLPECAIPR VASELGWSAS DKPGQDNSCY QQKI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.